- Ezetimibe INT A
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- $0.00 / 25Kg/Drum
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2023-01-31
- CAS:189028-95-3
- Min. Order: 1Kg/Drum
- Purity: 99%
- Supply Ability: 5000KG
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| (4S)-3-[(5R)-5-(4-FLUOROPHENYL)-5-HYDROXYPENTANOYL]-4-PHENYL-1,3-OXAZOLIDIN-2-ONE Basic information |
| (4S)-3-[(5R)-5-(4-FLUOROPHENYL)-5-HYDROXYPENTANOYL]-4-PHENYL-1,3-OXAZOLIDIN-2-ONE Chemical Properties |
Boiling point | 572.7±50.0 °C(Predicted) | density | 1.297 | storage temp. | 2-8°C | solubility | Chloroform (Sparingly), Methanol (Slightly) | form | Solid | pka | 14.17±0.20(Predicted) | color | White to Off-White |
| (4S)-3-[(5R)-5-(4-FLUOROPHENYL)-5-HYDROXYPENTANOYL]-4-PHENYL-1,3-OXAZOLIDIN-2-ONE Usage And Synthesis |
Description | (4S)-3-[(5R)-5-(4-FLUOROPHENYL)-5-HYDROXYPENTANOYL]-4-PHENYL-1, 3-OXAZOLIDIN-2-ONE is a derivative of 2-oxazolidine, which is an effective antimicrobial. It can be used as a pharmaceutical intermediate for the preparation of ezetimibe which is a drug used to lower the patients’ plasma cholesterol levels. | Chemical Properties | Solid | Uses | 3-[(5S)-(4-Fluorophenyl)-5-hydroxypentanoyl]-(4S)-phenyl-1,3-oxazolidin-2-one is an intermediate of Ezetimibe (E975000, E975002), an antihyperlipoproteinemic. A cholesterol absorption inhibitor. | References | http://www.cphi-online.com/ezetimibe-intermediate-4s3-prod587443.html
https://en.wikipedia.org/wiki/2-Oxazolidone |
| (4S)-3-[(5R)-5-(4-FLUOROPHENYL)-5-HYDROXYPENTANOYL]-4-PHENYL-1,3-OXAZOLIDIN-2-ONE Preparation Products And Raw materials |
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