Aurora Kinase Inhibitor II manufacturers
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| | Aurora Kinase Inhibitor II Basic information |
| Product Name: | Aurora Kinase Inhibitor II | | Synonyms: | Aurora kinase inhibitor-2;IUN-70219;N-(4-((6,7-Dimethoxyquinazolin-4-yl)amino)phenyl)benzamide;inhibit,Aurora-A,Aurora kinase inhibitor2,Aurora Kinase,ATP-competitive,Aurora kinase inhibitor 2,Aurora kinase inhibitor-2,Aurora-B,Inhibitor;Benzamide, N-[4-[(6,7-dimethoxy-4-quinazolinyl)amino]phenyl]-;Aurora kinase inhibitor-2, 10 mM in DMSO | | CAS: | 331770-21-9 | | MF: | C23H20N4O3 | | MW: | 400.43 | | EINECS: | | | Product Categories: | | | Mol File: | 331770-21-9.mol |  |
| | Aurora Kinase Inhibitor II Chemical Properties |
| Boiling point | 518.6±50.0 °C(Predicted) | | density | 1.321±0.06 g/cm3(Predicted) | | storage temp. | 4°C, protect from light | | solubility | DMF:0.25(Max Conc. mg/mL);0.62(Max Conc. mM)
DMF:PBS(pH7.2) (1:2):0.33(Max Conc. mg/mL);0.82(Max Conc. mM)
DMSO:2.5(Max Conc. mg/mL);6.2(Max Conc. mM) | | form | A crystalline solid | | pka | 13.01±0.70(Predicted) | | color | White to yellow |
| | Aurora Kinase Inhibitor II Usage And Synthesis |
| Description | The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis. Aurora kinase inhibitor II is a cell-permeable anilinoquinazoline that blocks the activity of Aurora A (IC50 = 0.39 μM). In MCF-7 cells, it blocks proliferation with an IC50 value of 1.25 μM. |
| | Aurora Kinase Inhibitor II Preparation Products And Raw materials |
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