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GPR39-C3

GPR39-C3 Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:GPR39-C3
CAS:1621175-65-2
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:TC-G-1008
CAS:1621175-65-2
Purity:99% Package:1mg;41USD|2mg;59USD|5mg;92USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 +8613203830695
Email: laboratory@coreychem.com
Products Intro: Product Name:GPR39-C3
CAS:1621175-65-2
Purity:Min98%HPLC/LC Package:1KG;1USD
Company Name: Zhejiang J&C Biological Technology Co.,Limited
Tel: +1-2135480471 +1-2135480471
Email: sales@sarms4muscle.com
Products Intro: Product Name:GPR39-C3
CAS:1621175-65-2
Purity:99% Package:5KG;1KG Remarks:GPR39-C3
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:TC-G-1008
CAS:1621175-65-2
Purity:98% Package:5mg Remarks:V15925

GPR39-C3 manufacturers

  • TC-G-1008
  • TC-G-1008 pictures
  • $41.00 / 1mg
  • 2024-11-19
  • CAS:1621175-65-2
  • Min. Order:
  • Purity: 99%
  • Supply Ability: 10g
GPR39-C3 Basic information
Product Name:GPR39-C3
Synonyms:GPR39-C3;TC-G-1008;N-[3-Chloro-4-[[[2-(methylamino)-6-(2-pyridinyl)-4-pyrimidinyl]amino]methyl]phenyl]methanesulfonamide;GPR39C3;GPR39 C3;CS-2374;TC-G-1008 (GPR39-C3);Methanesulfonamide, N-[3-chloro-4-[[[2-(methylamino)-6-(2-pyridinyl)-4-pyrimidinyl]amino]methyl]phenyl]-;N-(3-Chloro-4-(((2-(methylamino)-6-(pyridin-2-yl)pyrimidin-4-yl)amino)methyl)phenyl)methanesulfonamide
CAS:1621175-65-2
MF:C18H19ClN6O2S
MW:418.9
EINECS:
Product Categories:
Mol File:1621175-65-2.mol
GPR39-C3 Structure
GPR39-C3 Chemical Properties
Boiling point 662.1±65.0 °C(Predicted)
density 1.462±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO:63.97(Max Conc. mg/mL);152.72(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:5):0.16(Max Conc. mg/mL);0.38(Max Conc. mM)
Ethanol:2.0(Max Conc. mg/mL);4.77(Max Conc. mM)
form A crystalline solid
pka7.43±0.10(Predicted)
color White to off-white
Safety Information
MSDS Information
GPR39-C3 Usage And Synthesis
DescriptionGPR39-C3 is a potent agonist of the orphan G protein-coupled receptor GPR39 with EC50 values of 0.8 and 0.4 nM for cAMP production in HEK293 cells expressing human and rat receptors, respectively. It is selective for GPR39 over a panel of kinases (IC50s = >10 μM), ghrelin and neurotensin-1 receptors (IC50s = >30 μM), and a variety of enzymes, transporters, or G protein-coupled receptors. GPR39-C3 increases secretion of glucagon-like peptide 1 (GLP-1; ) in STC-1 mouse enteroendocrine cells (EC50 = 0.06 μM) and is protective against cytokine-induced cell death in INS-1E rat insulinoma cells (EC50 = 0.02 μM). In vivo, GPR39-C3 (30 mg/kg) increases the amount of active GLP-1 in sera by 6-fold in glucose-challenged mice when administered concurrently with a dipeptidyl peptidase 4 (DPP-4) inhibitor.
UsesTC-G 1008 is the first potent, selective, and orally bioavailable GPR39 agonist.
storageStore at +4°C
GPR39-C3 Preparation Products And Raw materials
Tag:GPR39-C3(1621175-65-2) Related Product Information

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