| Company Name: |
J & K SCIENTIFIC LTD.
|
| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:PPADS TetrasodiuM
CAS:192575-19-2
Package:250Mg,25Mg
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| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
|
| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:PPADS TETRASODIUM SALT
CAS:192575-19-2
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
ShangHai Caerulum Pharma Discovery Co., Ltd.
|
| Tel: |
18149758185 18149758185 |
| Email: |
sales-cpd@caerulumpharma.com |
| Products Intro: |
Product Name:PPADS tetrasodium salt
CAS:192575-19-2
Purity:98% Package:1g;10g;100g
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PPADS TETRASODIUM SALT manufacturers
- PPADS tetrasodium
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- $44.00 / 1mg
-
2024-10-28
- CAS:192575-19-2
- Min. Order:
- Purity: ≥95%
- Supply Ability: 10g
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| | PPADS TETRASODIUM SALT Basic information |
| | PPADS TETRASODIUM SALT Chemical Properties |
| storage temp. | −20°C | | solubility | H2O: >10 mg/mL | | form | solid | | color | red to orange | | Water Solubility | Soluble to 100 mM in water | | Stability: | Unstable in Aqueous Solution |
| | PPADS TETRASODIUM SALT Usage And Synthesis |
| Uses | PPADS Tetrasodium is an non-selective purinergic antagonists of P2 ATP receptors. PPADS Tetrasodium is also a potential neuroprotective agents for the treatment of autoimmune and demyelinating disease. | | Uses | P2X and P2Y purinergic receptors are ATP-sensitive receptors responsible for mediating a large variety of excitatory postsynaptic responses including fast transmission at central synapses, contraction of smooth muscle cells, platelet aggregation, macrophage activation, and apoptosis. PPADS is a non-selective P2 purinergic antagonist that blocks recombinant P2X1-5 (IC50s = 1-2.6 μM), native P2Y2-like (IC50 = ~0.9 mM), and recombinant P2Y4 (IC50 = ~15 mM) receptors. PPADS antagonism of ATP-sensitive P2 receptors produces neuroprotective effects in an ischemia model with permanent middle cerebral artery occlusion in spontaneously hypertensive rats. | | Definition | ChEBI: Tetrasodium 5'-phosphonatopyridoxal-6-azobenzene-2,4-disulfonate is an organic sodium salt that is the tetrasodium salt of 5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid It has a role as a purinergic receptor P2X antagonist. It is an organic sodium salt and an organosulfonate salt. It contains a 5'-phosphonatopyridoxal-6-azobenzene-2,4-disulfonate. | | Biological Activity | Non-selective P2 purinoceptor antagonist which blocks responses at both pre- and post-junctional sites. | | storage | -20°C (desiccate) |
| | PPADS TETRASODIUM SALT Preparation Products And Raw materials |
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