- P-NITROPHENYL BUTYRATE
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- $1.00 / 1KG
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2020-01-01
- CAS:2635-84-9
- Min. Order: 1KG
- Purity: 95-99%
- Supply Ability: 1ton
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| | P-nitrophenyl butyrate Basic information |
| Product Name: | P-nitrophenyl butyrate | | Synonyms: | 4-Nitrophenyl butyrate,p-Nitrophenyl butyrate, Butyric acid 4-nitrophenyl ester;4-NITROPHENYL BUTYRATE;P-NITROPHENYL BUTYRATE;Butanoic acid, 4-nitrophenyl ester;PARA-NITROPHENYLBUTYRATE;p-Nitrophenyl butyrate, Butyric acid 4-nitrophenyl ester;4-Nitrophenol butyrate;Butanoic acid p-nitrophenyl ester | | CAS: | 2635-84-9 | | MF: | C10H11NO4 | | MW: | 209.2 | | EINECS: | 258-258-3 | | Product Categories: | | | Mol File: | 2635-84-9.mol |  |
| | P-nitrophenyl butyrate Chemical Properties |
| Boiling point | 184-185 °C | | density | 1.19 g/mL at 20 °C(lit.) | | storage temp. | -20°C | | solubility | chloroform: 0.1 g/mL, clear, faintly yellow | | form | A neat oil | | color | Colorless to light yellow | | BRN | 1879729 | | InChIKey | DVDUMIQZEUTAGK-UHFFFAOYSA-N |
| Hazard Codes | Xi | | Risk Statements | 43 | | Safety Statements | 36/37 | | WGK Germany | 3 | | HS Code | 29156000 |
| | P-nitrophenyl butyrate Usage And Synthesis |
| Description | P-nitrophenyl butyrate also kown as 4-nitrophenyl butyrate, is a probe for lipase activity. It is hydrolyzed by lipase in the water ambient condition, giving rise to p-nitrophenol and butyric acid. P-nitrophenol actually occurs in the anionic form, p-nitrophenolate, giving a yellowish coloration and absorbing light at 410 nm in an alkaline buffer such as Tris-HCl pH 7.5. | | Uses | 4-Nitrophenyl butyrate is a substrate for esterase, and lipase enzyme. Hydrolysis of 4-nitrophenyl butyrate by these enzymes releases the chromophore, 4-nitrophenolate which is spectrophotometrically analysed at 415 nm. | | Definition | ChEBI: P-nitrophenyl butyrate is a butyrate ester resulting from the formal condensation of the hydroxy group of 4-nitrophenol with the carboxy group of butyric acid. It is a butyrate ester and a C-nitro compound. It is functionally related to a 4-nitrophenol. | | References | [1] POHANKA M. Biosensors and Bioassays Based on Lipases, Principles and Applications, a Review.[J]. Molecules, 2019. DOI:10.3390/molecules24030616.
[2] WENTING SHANG. Enzymatic hydrolysis of p-nitrophenyl butyrate in CO2-based micelle systems[J]. Journal of chemical technology and biotechnology, 2013, 89 9: 1324-1329. DOI:10.1002/jctb.4246.
[3] SIGRUN H. STERRI Frode F Bj?rn A Johnsen. A radiochemical assay method for carboxylesterase, and comparison of enzyme activity towards the substrates methyl [1-14C] butyrate and 4-nitrophenyl butyrate[J]. Biochemical pharmacology, 1985, 34 15: Pages 2779-2785. DOI:10.1016/0006-2952(85)90579-9.
[4] BISHNU PRASAD PANDEY. Bergenia pacumbis from Nepal, an astonishing enzymes inhibitor.[J]. BMC Complementary Medicine and Therapies, 2020: 198. DOI:10.1186/s12906-020-02989-2. |
| | P-nitrophenyl butyrate Preparation Products And Raw materials |
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