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ChemicalBook > Product Catalog >Chemical Reagents >Silane reagent >N-Methyl-N-(trimethylsilyl)trifluoroacetamide

N-Methyl-N-(trimethylsilyl)trifluoroacetamide

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Products Intro: Product Name:N-Methyl-N- (trimethylsilyl) Trifluoroacetamide
CAS:24589-78-4
Purity:99% Package:1KG;5.00;USD|10KG;3.00;USD|50KG;2.00;USD
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Products Intro: Product Name:N-Methyl-N-(trimethylsilyl)trifluoroacetamide
CAS:24589-78-4
Purity:99% Package:1kg;5.9USD|100kg;4.5USD|1000kg;3.2USD
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CAS:24589-78-4
Purity:99% Package:1KG ;10KG ;100KG Remarks:Low M.W.Organic Silanes Professor
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Products Intro: Product Name:CAS24589-78-4 N-methyl-N-(trimethylsilyl)trifluoroacetamide
CAS:24589-78-4
Purity:99% Package:25KG;5KG;1KG
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Products Intro: Product Name:N-Methyl-N-(trimethylsilyl)trifluoroacetamide
CAS:24589-78-4

N-Methyl-N-(trimethylsilyl)trifluoroacetamide manufacturers
N-Methyl-N-(trimethylsilyl)trifluoroacetamide Basic information
Product Name:N-Methyl-N-(trimethylsilyl)trifluoroacetamide
Synonyms:N-METHYL-N-(TRIMETHYLSILYL)TRIFLUOROACETAMIDE W. 1% TMCS;N-METHYL-N-(TRIMETHYLSILYL)TRIFLUORO-ACE TAMIDE, DERIVATIZATION GRADE;N-METHYL-N-TRIMETHYLSILYLTRIFLUOROACET-A MIDE, FOR GC;N-METHYL-N-TRIMETHYLSILYLTRIFLUOROACETAM, 10x1ML PACKSIZE;N-METHYL-N-(TRIMETHYLSILYL)TRIFLUOROACETAMIDE 98%;N-Methyl-N-(Trimethylsily)Trifluoroacetamide;N-Methyl-N-(trimethylsilyl)trifluoroacetamide, 98;MSTFA~N-Trimethylsilyl-N-methyltrifluoroacetamide
CAS:24589-78-4
MF:C6H12F3NOSi
MW:199.25
EINECS:246-331-6
Product Categories:Silylation Reagents;Amines;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Silylation (GC Derivatizing Reagents);Si-N Compounds;Trimethylsilylation (GC Derivatizing Reagents);Reagents for SilylationProtection and Derivatization;Silicon-BasedAnalytical/Chromatography;Protecting and Derivatizing Reagents;Silylation Reagents;Derivatization Reagents;Derivatization Reagents GC;Reagents for SilylationAnalytical/Chromatography;Analytical Chemistry;GC Derivatizing Reagents;Si (Classes of Silicon Compounds);Silylacetamides;Amines, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:24589-78-4.mol
N-Methyl-N-(trimethylsilyl)trifluoroacetamide Structure
N-Methyl-N-(trimethylsilyl)trifluoroacetamide Chemical Properties
Melting point 98-100°C
Boiling point 130132°C
density 1.075 g/mL at 25 °C(lit.)
vapor density >1 (vs air)
vapor pressure 8.8 mm Hg ( 27 °C)
refractive index n20/D 1.383
Fp 77 °F
storage temp. 2-8°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
form Liquid
pka-1.34±0.70(Predicted)
color Clear colorless to light yellow
Specific Gravity1.076
Water Solubility reacts
Sensitive Moisture Sensitive
Hydrolytic Sensitivity7: reacts slowly with moisture/water
BRN 1941550
InChIKeyMSPCIZMDDUQPGJ-UHFFFAOYSA-N
CAS DataBase Reference24589-78-4(CAS DataBase Reference)
EPA Substance Registry SystemAcetamide, 2,2,2-trifluoro-N-methyl-N-(trimethylsilyl)- (24589-78-4)
Safety Information
Hazard Codes Xi,F,T,N
Risk Statements 10-36/37/38-61-50/53-51/53
Safety Statements 26-36-37/39-16-45-53-61
RIDADR UN 1993 3/PG 3
WGK Germany 3
RTECS AC9800000
F 10-21
Hazard Note Flammable
TSCA T
HazardClass 3
PackingGroup III
HS Code 29319090
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
N-Methyl-N-(trimethylsilyl)trifluoroacetamide Usage And Synthesis
Chemical PropertiesClear colorless to light yellow liquid
UsesA new metabolite of Famprofazone in humans.
UsesN-Methyl-N-(trimethylsilyl)trifluoroacetamide is used as a silylating reagent that forms volatile derivatives for GC-MS analysis. It acts as a pharmaceutical intermediate and metabolite of Famprofazone in humans. It is also used in the detection of steroid hormones 17-alfa-ethynylestradiol and estrone.
DefinitionChEBI: An N-silyl compound that is N-methyltrifluoroacetamide in which the amide nitrogen is replaced by a trimethylsilyl group. N-methyl-N-(trimethylsilyl)trifluoroacetamide is a derivat sation agent used in gas chromatography/mass spectrometry applications.
General DescriptionN-Methyl-N-(trimethylsilyl)trifluoroacetamide (MSTFA) is a derivatizing reagent. It can be used as alternatives to diazomethane.
Purification MethodsFractionate the amide through a 40mm Vigreux column (p 11). Usually it contains ca 1% of methyl trifluoroacetamide and 1% of other impurities which can be removed by gas chromatography or fractionating using a spinning band column. [Donike J Chromatogr 42 103 1969, Donike J Chromatogr 103 91 1975, Beilstein 4 IV 4011.]
N-Methyl-N-(trimethylsilyl)trifluoroacetamide Preparation Products And Raw materials
Raw materialsN,O-Bis(trimethylsilyl)acetamide-->N-Methyl-2,2,2-trifluoroacetamide
Tag:N-Methyl-N-(trimethylsilyl)trifluoroacetamide(24589-78-4) Related Product Information
Thiophanate-methyl Bensulfuron methyl N-Methylacetamide Trifluoroacetamide Trifluoroacetamidine TRIMETHYLSILANE Hexamethyldisilane Methyltriacetoxysilane Methyl acetate Methyl acrylate Methylparaben Iodotrimethylsilane Azidotrimethylsilane Dichlorodimethylsilane Kresoxim-methyl Methyltriethoxysilane Methyltris(methylethylketoxime)silane N-(Trimethylsilyl)acetamide Mstfa Reagent