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916232-21-8(GS 143)

916232-21-8 Basic information More..
Product Name:GS 143
Synonyms:GS 143;4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]benzoic acid;4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid;E2 conjugating enzyme,inhibit,IκBα,Th2,Ubiquitin conjugating enzyme,GS143,Ubiquitin ligase,IL-4,IκB kinase,βTrCP1,Nuclear factor-kappaB,eosinophil,Ubiquitin activating enzyme,Nuclear factor-κB,I kappa B kinase,NF-κB,E3 ligating enzyme,IKK,E1 activating enzyme,anti-asthma,E1/E2/E3 Enzyme,ubiquitination,Inhibitor,airway,inflammation;Benzoic acid, 4-[4-[[5-(2-fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]-;GS143, 10 mM in DMSO
CAS:916232-21-8
MF:C28H19FN2O4
MW:466.46
EINECS:
Mol File:Mol File
916232-21-8
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Products Intro: Product Name:GS143；GS-143;GS 143
CAS:916232-21-8
Package:1 mL * 10mM (in DMSO)；10 mg；100 mg；2 mg；200 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
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CAS:916232-21-8
Purity:≥98% by HPLC Remarks:GS 143 is a β-TrCP1 ligase inhibitor. GS 143 exhibits inhibitory effects on IκBα ubiquitination (IC50 = 5.2 μM), LPS-induced expression of inflammatory cytokines in human myelomonocytic cells, antigen
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CAS:916232-21-8
Purity:>=98%(HPLC) Package:$173.9/10mg;$543.9/50mg;$924.9/100mg;Bulk package Remarks:98%(HPLC)
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Products Intro: Product Name:4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]-benzoic Acid
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