2',3,4',5,7-Pentahydroxyflavon
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- CAS-Nr.
- 480-16-0
- Bezeichnung:
- 2',3,4',5,7-Pentahydroxyflavon
- Englisch Name:
- MORIN
- Synonyma:
- MONOUNDECANOIN;2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chroMen-4-one;MORIN;FUSTIC;CI 75660;al-morin;Morin-RM;boisd’arc;Morin,98%;Morin(SH)
- CBNumber:
- CB0316037
- Summenformel:
- C15H10O7
- Molgewicht:
- 302.24
- MOL-Datei:
- 480-16-0.mol
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2',3,4',5,7-Pentahydroxyflavon Eigenschaften
- Schmelzpunkt:
- 299-300 °C (dec.)(lit.)
- Siedepunkt:
- 363.28°C (rough estimate)
- Dichte
- 1.3616 (rough estimate)
- Brechungsindex
- 1.4790 (estimate)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- L?slichkeit
- methanol: 50 mg/mL
- Aggregatzustand
- powder
- Colour Index
- 75660
- pka
- 6.30±0.40(Predicted)
- Farbe
- yellow
- Wasserl?slichkeit
- 0.25g/L(20 ºC)
- Merck
- 6269
- Stabilit?t:
- Stable. Incompatible with strong oxidizing agents.
- InChIKey
- YXOLAZRVSSWPPT-UHFFFAOYSA-N
- LogP
- 1.27-1.54 at 37℃ and pH7.4
- CAS Datenbank
- 480-16-0(CAS DataBase Reference)
- EPA chemische Informationen
- Morin (480-16-0)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xi,T |
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| R-S?tze: |
36/37/38-25 |
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| S-S?tze: |
26-36-45 |
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| RIDADR |
UN 2811 6.1 / PGIII |
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| WGK Germany |
3 |
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| RTECS-Nr. |
LK8749000 |
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| F |
8-10-23 |
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| HS Code |
29329990 |
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| Toxizit?t |
LD50 intraperitoneal in mouse: 555mg/kg |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 3 |
Achtung |
![GHS hazard pictograms]() src="/GHS06.jpg" width="20" height="20" /> |
P264, P270, P301+P310, P321, P330,P405, P501 |
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| Sicherheit |
| P301+P310 |
BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
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2',3,4',5,7-Pentahydroxyflavon Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
yellow to brown powder
Verwenden
Morin is a natural pentahydroxyflavonol with antioxidant activity. It reduces CD36 expression and oxLDL uptake in U937-derived macrophages, inhibits PIM-1 kinase in vitro (IC50 = 2.7 μM), and reduces the activity of cytochrome P450 isoform 3A4 in liver microsomes. Through these and other actions, morin has anti-oxidant, anti-inflammatory, and other actions in animal models.[Cayman Chemical]
Definition
ChEBI: A pentahydroxyflavone that is 7-hydroxyflavonol bearing three additional hydroxy substituents at positions 2' 4' and 5.
Sicherheitsprofil
Moderately toxic by
intraperitoneal route. Mutation data
reported. When heated to decomposition it
emits acrid smoke and irritating fumes.
l?uterung methode
Stir morin at room temperature with ten times its weight of absolute EtOH, then leave overnight to settle. Filter it off, and evaporate under a heat lamp to one-tenth its volume. An equal volume of water is added, and the precipitated morin is filtered off, dissolved in the minimum amount of EtOH and again precipitated with an equal volume of water. The precipitate is filtered off, washed with water and dried at 110o for 1hour (yield ca 2.5%.). [Perkins & Kalkwarf Anal Chem 28 1989 1956.] It complexes with W and Zr. [Beilstein 18 H 239, 18 III/IV 3468, 18/5 V 492.]
2',3,4',5,7-Pentahydroxyflavon Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2',3,4',5,7-Pentahydroxyflavon Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 326)Lieferanten
480-16-0(2',3,4',5,7-Pentahydroxyflavon)Verwandte Suche:
- TIMTEC-BB SBB008853
- MORIN
- FUSTIC
- CI 75660
- CI NO 75660
- 3,5,7,2',4'-PENTAHYDROXYFLAVONE
- 2',3,4',5,7-PENTAHYDROXYFLAVONE
- 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4h-1-benzopyran-4-on
- 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-Benzopyran-4-one
- MORIN, REAG
- MORIN (2',3,4',5,7-pentahydroxyflavone)
- Morus alba L
- 2’,3,4’,5,7-pentahydroxy-flavon
- 2’,4’,3,5,7-pentahydroxyflavone
- 2’-hydroxypelargidenolon1522
- 2-2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4h-1-benzopyran-4-on
- 3,5,7,2’,4’-pentahydroxyflavonol
- abcolfustic
- Morin anhydrous
- 2-(2,4-Dihydroxyphenyl)
- -3,5,7-trihydroxy-4H-chromen-4-one
- al-morin
- boisd’arc
- zlutprirodni11
- MorinGr-(2'3,4',5,7-Pentahydroxyflavone)
- 4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-
- 35746PENTAHYDROXYFLAVONEDIHYDRATE
- MORIN WITH HPLC
- MORIN extrapure AR
- C.I.Natural Yellow 8
- Morin,98%
- 3,5,7-Trihydroxy-2-(2,4-dihydroxyphenyl)-4H-chromen-4-one
- Calico Yellow
- Toxylon pomiferum
- Morin Hydrate (AluminiumIonophore I, C.I. 75660) extrapure AR, 98%
- Morin, 98%, from bark of Moraceae
- 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chroMen-4-one
- MONOUNDECANOIN
- Morin transfer
- Mulberry pigment
- 3-hydroxy-5-(6-hydroxy-7,7-dimethyl-6,7-dihydro-5H-furo[3,2-g]chromen-2-yl)phenyl beta-D-xylopyranoside
- Morin(SH)
- Morin-RM
- 480-16-0
- C15H10O7
- Flavonoids
- Inhibitors
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Biochemistry
- Flavonoids
- Flavanols
