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Taurohyodeoxycholic acid sodium salt hydrate

price.
  • ￥39600 - ￥124100
  • 化學(xué)名:
  • 英語名: Taurohyodeoxycholic acid sodium salt hydrate
  • 別名:
  • CAS番號(hào): 38411-85-7
  • 分子式: C26H46NNaO6S
  • 分子量: 523.7
  • EINECS:
  • MDL Number:MFCD00271496
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プロパティ

貯蔵溫度  :Store at -20°C
溶解性 :DMF: 30 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml
外見  :A crystalline solid
色 :White to off-white

安全情報(bào)

絵表示(GHS):
注意喚起語:
危険有害性情報(bào):
コード 危険有害性情報(bào) 危険有害性クラス 區(qū)分 注意喚起語 シンボル P コード
注意書き:

説明

Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid . THDCA decreases the size and weight of human gallstones in vitro. It increases bile flow, biliary cholesterol secretion, and biliary lipid secretion in rats. Co-administration of THDCA with taurochenodeoxycholic acid (TCDCA; ) prevents TCDCA-induced hepatotoxicity, increasing bile flow as well as biliary acid and phospholipid secretion in rats. THDCA also reduces myeloperoxidase activity, expression of TNF-α and IL-6, and colonic damage in a mouse model of TNBS-induced ulcerative colitis.