ml390
|
- $49 - $410
- Product name: ml390
- CAS: 2029049-79-2
- MF: C21H21F3N2O3
- MW: 406.4
- EINECS:-0
- MDL Number:
- Synonyms:ml390;Benzamide, N-[3-oxo-3-[[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]amino]propyl]-4-(trifluoromethoxy)-;ER-HoxA9,Dihydroorotate Dehydrogenase,inhibit,AML,ML 390,differentiatio,U937,DHODH,ML390,myeloid,ML-390,Inhibitor,THP1;(R)-N-(3-Oxo-3-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)propyl)-4-(trifluoromethoxy)benzamide
9 prices
Selected condition：
Brand
- ApexBio Technology
- Cayman Chemical
- ChemScene
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- ManufacturerApexBio Technology
- Product numberB7824
- Product descriptionML390
- Packaging5mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21395
- Product descriptionML-390 ≥98%
- Packaging5mg
- Price$49
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21395
- Product descriptionML-390 ≥98%
- Packaging10mg
- Price$87
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21395
- Product descriptionML-390 ≥98%
- Packaging25mg
- Price$190
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21395
- Product descriptionML-390 ≥98%
- Packaging50mg
- Price$286
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5978
- Product descriptionML390 98.77%
- Packaging5mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5978
- Product descriptionML390 98.77%
- Packaging10mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5978
- Product descriptionML390 98.77%
- Packaging50mg
- Price$230
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5978
- Product descriptionML390 98.77%
- Packaging100mg
- Price$410
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ApexBio Technology | B7824 | ML390 | 5mg | $190 | 2021-12-16 | Buy |
| Cayman Chemical | 21395 | ML-390 ≥98% | 5mg | $49 | 2024-03-01 | Buy |
| Cayman Chemical | 21395 | ML-390 ≥98% | 10mg | $87 | 2024-03-01 | Buy |
| Cayman Chemical | 21395 | ML-390 ≥98% | 25mg | $190 | 2024-03-01 | Buy |
| Cayman Chemical | 21395 | ML-390 ≥98% | 50mg | $286 | 2024-03-01 | Buy |
| ChemScene | CS-5978 | ML390 98.77% | 5mg | $70 | 2021-12-16 | Buy |
| ChemScene | CS-5978 | ML390 98.77% | 10mg | $90 | 2021-12-16 | Buy |
| ChemScene | CS-5978 | ML390 98.77% | 50mg | $230 | 2021-12-16 | Buy |
| ChemScene | CS-5978 | ML390 98.77% | 100mg | $410 | 2021-12-16 | Buy |
Properties
Boiling point :599.7±50.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥40.6 mg/mL in DMSO; insoluble in H2O; ≥17.47 mg/mL in EtOH
form :solid
pka :13.65±0.46(Predicted)
color :White to off-white
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥40.6 mg/mL in DMSO; insoluble in H2O; ≥17.47 mg/mL in EtOH
form :solid
pka :13.65±0.46(Predicted)
color :White to off-white
Safety Information
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Description
ML-390 is an inhibitor of dihydroorotate dehydrogenase (DHODH), the enzyme that converts dihydroorotate to orotate during de novo pyrimidine synthesis. In acute myeloid leukemia, leukemic myeloblast development is halted at an immature stage leading to perpetual self-renewal rather than differentiation. ML-390 induces differentiation in the acute myeloid leukemia cell lines U937 (murine) and THP-1 (human) cell lines with an EC50 value of approximately 2 μM.More related product prices
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