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ChemicalBook >> CAS DataBase List >> cis-4-Hydroxy-L-proline

cis-4-Hydroxy-L-proline

cis-4-Hydroxy-L-proline price.
  • $9 - $3552
  • Product name: cis-4-Hydroxy-L-proline
  • CAS: 618-27-9
  • MF: C5H9NO3
  • MW: 131.13
  • EINECS:210-542-1
  • MDL Number:MFCD00064319
  • Synonyms:(S)-Allo-hydroxyproline;cis-4-Hydroxy-L-proline collagen synthesis inhibitor;L-ALLO-4-HYDROXY-2-PYRROLIDINECARBOXYLIC ACID;L-ALLO-4-HYDROXY-2-PYRROLIDINECARBOXYLLIC ACID;L-ALLO-HYDROXYPROLINE;CIS-4-HYDROXY-L-PROLINE;CIS-L-4-HYDROXYPROLINE;CIS-HYDROXYPROLINE
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  • ManufacturerACHEMBLOCK
  • Product numberO30697
  • Product description(2S,4S)-4-hydroxypyrrolidine-2-carboxylicacid 95%
  • Packaging5G
  • Price$95
  • Updated2021-12-16
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  • ManufacturerACHEMBLOCK
  • Product numberO30697
  • Product description(2S,4S)-4-hydroxypyrrolidine-2-carboxylicacid 95%
  • Packaging25G
  • Price$285
  • Updated2021-12-16
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  • ManufacturerActivate Scientific
  • Product numberAS3728-A
  • Product descriptionCis-4-Hydroxy-L-proline 98+%
  • Packaging1g
  • Price$42
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberMT-15523
  • Product descriptioncis-4-Hydroxy-L-proline 98%
  • Packaging10g
  • Price$635
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ93503
  • Product descriptioncis-4-Hydroxy-L-proline
  • Packaging1g
  • Price$25
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ93503
  • Product descriptioncis-4-Hydroxy-L-proline
  • Packaging100g
  • Price$650
  • Updated2021-12-16
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  • ManufacturerAlfa Aesar
  • Product numberH27194
  • Product descriptioncis-4-Hydroxy-L-proline, 99%
  • Packaging250mg
  • Price$162.65
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberH27194
  • Product descriptioncis-4-Hydroxy-L-proline, 99%
  • Packaging1g
  • Price$504.65
  • Updated2024-03-01
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  • ManufacturerAlichem
  • Product number618279
  • Product description(2S,4S)-4-Hydroxypyrrolidine-2-carboxylicacid
  • Packaging10g
  • Price$262.6
  • Updated2021-12-16
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  • ManufacturerAlichem
  • Product number618279
  • Product description(2S,4S)-4-Hydroxypyrrolidine-2-carboxylicacid
  • Packaging25g
  • Price$551.2
  • Updated2021-12-16
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  • ManufacturerAlichem
  • Product number618279
  • Product description(2S,4S)-4-Hydroxypyrrolidine-2-carboxylicacid
  • Packaging100g
  • Price$1462.8
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA209063
  • Product description(2S,4S)-4-Hydroxypyrrolidine-2-carboxylicacid 98%
  • Packaging250mg
  • Price$9
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA209063
  • Product description(2S,4S)-4-Hydroxypyrrolidine-2-carboxylicacid 98%
  • Packaging1g
  • Price$19
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA209063
  • Product description(2S,4S)-4-Hydroxypyrrolidine-2-carboxylicacid 98%
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  • Price$66
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA209063
  • Product description(2S,4S)-4-Hydroxypyrrolidine-2-carboxylicacid 98%
  • Packaging10g
  • Price$124
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA209063
  • Product description(2S,4S)-4-Hydroxypyrrolidine-2-carboxylicacid 98%
  • Packaging25g
  • Price$283
  • Updated2021-12-16
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Manufacturer Product number Product description Packaging Price Updated Buy
ACHEMBLOCK O30697 (2S,4S)-4-hydroxypyrrolidine-2-carboxylicacid 95% 5G $95 2021-12-16 Buy
ACHEMBLOCK O30697 (2S,4S)-4-hydroxypyrrolidine-2-carboxylicacid 95% 25G $285 2021-12-16 Buy
Activate Scientific AS3728-A Cis-4-Hydroxy-L-proline 98+% 1g $42 2021-12-16 Buy
AHH MT-15523 cis-4-Hydroxy-L-proline 98% 10g $635 2021-12-16 Buy
AK Scientific J93503 cis-4-Hydroxy-L-proline 1g $25 2021-12-16 Buy
AK Scientific J93503 cis-4-Hydroxy-L-proline 100g $650 2021-12-16 Buy
Alfa Aesar H27194 cis-4-Hydroxy-L-proline, 99% 250mg $162.65 2024-03-01 Buy
Alfa Aesar H27194 cis-4-Hydroxy-L-proline, 99% 1g $504.65 2024-03-01 Buy
Alichem 618279 (2S,4S)-4-Hydroxypyrrolidine-2-carboxylicacid 10g $262.6 2021-12-16 Buy
Alichem 618279 (2S,4S)-4-Hydroxypyrrolidine-2-carboxylicacid 25g $551.2 2021-12-16 Buy
Alichem 618279 (2S,4S)-4-Hydroxypyrrolidine-2-carboxylicacid 100g $1462.8 2021-12-16 Buy
Ambeed A209063 (2S,4S)-4-Hydroxypyrrolidine-2-carboxylicacid 98% 250mg $9 2021-12-16 Buy
Ambeed A209063 (2S,4S)-4-Hydroxypyrrolidine-2-carboxylicacid 98% 1g $19 2021-12-16 Buy
Ambeed A209063 (2S,4S)-4-Hydroxypyrrolidine-2-carboxylicacid 98% 5g $66 2021-12-16 Buy
Ambeed A209063 (2S,4S)-4-Hydroxypyrrolidine-2-carboxylicacid 98% 10g $124 2021-12-16 Buy
Ambeed A209063 (2S,4S)-4-Hydroxypyrrolidine-2-carboxylicacid 98% 25g $283 2021-12-16 Buy

Properties

Melting point :257 °C (dec.) (lit.)
alpha :-59 º (c=2, H2O)
Boiling point :242.42°C (rough estimate)
Density :1.3121 (rough estimate)
refractive index :-59 ° (C=2, H2O)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :soluble
form :Powder
pka :2.14±0.40(Predicted)
color :White to beige
Water Solubility :soluble
Merck :14,4840
BRN :81440
InChIKey :PMMYEEVYMWASQN-IMJSIDKUSA-N
CAS DataBase Reference :618-27-9(CAS DataBase Reference)
EPA Substance Registry System :L-Proline, 4-hydroxy-, (4S)- (618-27-9)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

cis-4-Hydroxy-L-proline (CHP) is a proline analog that inhibits collagen synthesis and has been used as an anticancer compound. CHP blocked myotube formation and expression of sarcomeric myosin heavy chain in C2C12 murine skeletal muscle cells. CHP inhibited proliferation of murine Panc02 pancreatic carcinoma cell line3 and rat pancreatic carcinoma cell line DSL6A. cis-4-Hydroxy-L-proline and other hydrosyl-L-prolines are important intermediates for chiral synthesis of potential drugs.