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ChemicalBook >> CAS DataBase List >> Troglitazone

Troglitazone

Troglitazone price.
  • $55 - $2318
  • Product name: Troglitazone
  • CAS: 97322-87-7
  • MF: C24H27NO5S
  • MW: 441.54
  • EINECS:
  • MDL Number:MFCD00878416
  • Synonyms:Troglitazone(CS-045);RESULIN(TM);ROMGLIZONE;5-(4-(6-hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl)thiazolidine-2 ;ci991 ;enzopyran-2-yl)methoxy)phenyl)methyl)- ;gr92132x ;rezulin
28 prices
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  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10mg
  • 50
  • 5mg
  • 25mg
  • 50mg
  • 100mg
  • 0.5g
  • 10
  • 1g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3565-M025
  • Product descriptionTroglitazone ≥98%
  • Packaging25mg
  • Price$210
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3565-M005
  • Product descriptionTroglitazone ≥98%
  • Packaging5mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1400
  • Product descriptionTroglitazone 98%
  • Packaging0.5g
  • Price$620
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberK752
  • Product descriptionTroglitazone
  • Packaging50mg
  • Price$397
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberK752
  • Product descriptionTroglitazone
  • Packaging1g
  • Price$2318
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3893
  • Product descriptionTroglitazone
  • Packaging10mg
  • Price$88
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3893
  • Product descriptionTroglitazone
  • Packaging50mg
  • Price$345
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFT28613
  • Product descriptionTroglitazone
  • Packaging10mg
  • Price$95
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFT28613
  • Product descriptionTroglitazone
  • Packaging50mg
  • Price$332.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number71750
  • Product descriptionTroglitazone ≥98%
  • Packaging5mg
  • Price$60
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number71750
  • Product descriptionTroglitazone ≥98%
  • Packaging10mg
  • Price$110
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number71750
  • Product descriptionTroglitazone ≥98%
  • Packaging50mg
  • Price$457
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number71750
  • Product descriptionTroglitazone ≥98%
  • Packaging100mg
  • Price$799
  • Updated2024-03-01
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  • ManufacturerChemenu
  • Product numberCM162783
  • Product descriptionTroglitazone 98%
  • Packaging50mg
  • Price$421
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1634
  • Product descriptionTroglitazone 99.53%
  • Packaging10mg
  • Price$102
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1634
  • Product descriptionTroglitazone 99.53%
  • Packaging50mg
  • Price$408
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3565-M025 Troglitazone ≥98% 25mg $210 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-3565-M005 Troglitazone ≥98% 5mg $55 2021-12-16 Buy
AHH API-1400 Troglitazone 98% 0.5g $620 2021-12-16 Buy
AK Scientific K752 Troglitazone 50mg $397 2021-12-16 Buy
AK Scientific K752 Troglitazone 1g $2318 2021-12-16 Buy
ApexBio Technology A3893 Troglitazone 10mg $88 2021-12-16 Buy
ApexBio Technology A3893 Troglitazone 50mg $345 2021-12-16 Buy
Biosynth Carbosynth FT28613 Troglitazone 10mg $95 2021-12-16 Buy
Biosynth Carbosynth FT28613 Troglitazone 50mg $332.5 2021-12-16 Buy
Cayman Chemical 71750 Troglitazone ≥98% 5mg $60 2024-03-01 Buy
Cayman Chemical 71750 Troglitazone ≥98% 10mg $110 2024-03-01 Buy
Cayman Chemical 71750 Troglitazone ≥98% 50mg $457 2024-03-01 Buy
Cayman Chemical 71750 Troglitazone ≥98% 100mg $799 2024-03-01 Buy
Chemenu CM162783 Troglitazone 98% 50mg $421 2021-12-16 Buy
ChemScene CS-1634 Troglitazone 99.53% 10mg $102 2021-12-16 Buy
ChemScene CS-1634 Troglitazone 99.53% 50mg $408 2021-12-16 Buy

Properties

Melting point :184-186°C
Boiling point :657.0±55.0 °C(Predicted)
Density :1.266±0.06 g/cm3(Predicted)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO: 20 mg/mL
form :solid
pka :6.34±0.50(Predicted)
color :white to yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :GXPHKUHSUJUWKP-UHFFFAOYSA-N
CAS DataBase Reference :97322-87-7(CAS DataBase Reference)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Troglitazone is a TZD which was approved for the treatment of insulin resistance and hyperglycemia in Type II diabetes, under the trade name Resulin?, but was withdrawn from the market due to hepatotoxicity. Troglitazone is a potent and selective PPARγ agonist. The EC50 values for transactivation of human and mouse PPARγ in a cell-based assay are 0.55 and 0.78 μM, respectively. In the same assay system, no activation of PPARα and PPARδ was observed at concentrations up to 10 μM. Troglitazone binds to the PPARγ ligand-binding domain (LBD) but fails to induce interaction of the PPARγ LBD with the transcriptional coactivators SRC-1, TIF2, AIB1, p300, or TRAP220. Troglitazone also induces cell cycle arrest and apoptosis in several cancer cell lines with an EC50 of 10 μM.

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