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ChemicalBook >> CAS DataBase List >> Tazarotene

Tazarotene

Tazarotene price.
  • $25 - $2194.5
  • Product name: Tazarotene
  • CAS: 118292-40-3
  • MF: C21H21NO2S
  • MW: 351.46
  • EINECS:601-516-4
  • MDL Number:MFCD00867628
  • Synonyms:3-pyridinecarboxylicacid,6-((3,4-dihydro-4,4-dimethyl-2h-1-benzothiopyran-6-y ;agn190168 ;6-[(3,4-Dihydro-4,4-dimethyl-2H-1-benzothiopyran)-6-yl]nicotinic acid ethyl ester;Tazorac/zorac;6-[2-(3,4-Dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl]- 3-pyridinecarboxylic Acid Ethyl Ester;Tazorac;Zorac;Tazarotene(Avage)
47 prices
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Brand
  • Activate Scientific
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • AstaTech
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Chemtos
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 0.1/ G
  • 0.5/ G
  • ManufacturerActivate Scientific
  • Product numberAS34824
  • Product descriptionTazarotene 95+%
  • Packaging100mg
  • Price$399
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ52615
  • Product descriptionTazarotene
  • Packaging100mg
  • Price$275
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberG739
  • Product descriptionTazarotene
  • Packaging100mg
  • Price$367
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberG739
  • Product descriptionTazarotene
  • Packaging250mg
  • Price$734
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA357060
  • Product descriptionTazarotene 97%
  • Packaging10mg
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA357060
  • Product descriptionTazarotene 97%
  • Packaging25mg
  • Price$32
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA357060
  • Product descriptionTazarotene 97%
  • Packaging50mg
  • Price$41
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA357060
  • Product descriptionTazarotene 97%
  • Packaging100mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA357060
  • Product descriptionTazarotene 97%
  • Packaging250mg
  • Price$111
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA357060
  • Product descriptionTazarotene 97%
  • Packaging1g
  • Price$275
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0005090
  • Product descriptionTAZAROTENE 95.00%
  • Packaging5MG
  • Price$816.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0005090
  • Product descriptionTAZAROTENE 95.00%
  • Packaging50MG
  • Price$2194.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5710
  • Product descriptionTazarotene
  • Packaging100mg
  • Price$237
  • Updated2021-12-16
  • Buy
  • ManufacturerAstaTech
  • Product number66588
  • Product descriptionTAZAROTENE 97%
  • Packaging0.5/ G
  • Price$962
  • Updated2021-12-16
  • Buy
  • ManufacturerAstaTech
  • Product number66588
  • Product descriptionTAZAROTENE 97%
  • Packaging0.1/ G
  • Price$275
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2708
  • Product descriptionTazarotene
  • Packaging100mg
  • Price$249
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Activate Scientific AS34824 Tazarotene 95+% 100mg $399 2021-12-16 Buy
AK Scientific J52615 Tazarotene 100mg $275 2021-12-16 Buy
AK Scientific G739 Tazarotene 100mg $367 2021-12-16 Buy
AK Scientific G739 Tazarotene 250mg $734 2021-12-16 Buy
Ambeed A357060 Tazarotene 97% 10mg $25 2021-12-16 Buy
Ambeed A357060 Tazarotene 97% 25mg $32 2021-12-16 Buy
Ambeed A357060 Tazarotene 97% 50mg $41 2021-12-16 Buy
Ambeed A357060 Tazarotene 97% 100mg $75 2021-12-16 Buy
Ambeed A357060 Tazarotene 97% 250mg $111 2021-12-16 Buy
Ambeed A357060 Tazarotene 97% 1g $275 2021-12-16 Buy
American Custom Chemicals Corporation API0005090 TAZAROTENE 95.00% 5MG $816.75 2021-12-16 Buy
American Custom Chemicals Corporation API0005090 TAZAROTENE 95.00% 50MG $2194.5 2021-12-16 Buy
ApexBio Technology A5710 Tazarotene 100mg $237 2021-12-16 Buy
AstaTech 66588 TAZAROTENE 97% 0.5/ G $962 2021-12-16 Buy
AstaTech 66588 TAZAROTENE 97% 0.1/ G $275 2021-12-16 Buy
AvaChem 2708 Tazarotene 100mg $249 2021-12-16 Buy

Properties

Melting point :95-98°C
Boiling point :499.8±45.0 °C(Predicted)
Density :1.22±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >15mg/mL
pka :0.04±0.29(Predicted)
form :powder
color :white to very faintly yellow
Merck :14,9081
CAS DataBase Reference :118292-40-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Tazarotene belongs to a third generation prescription topical retinoid. It is marketed in different forms including cream (brand name: Avage), foam (brand name: Fabuir) and gel (brand name: Tazorac). It is mainly used for the treatment of psoriasis, acne, and sun damaged skin. The detailed mechanisms of action of Tazarotene are still unclear. It is converted to its active form, the cognate carboxylic acid of tazarotene (AGN 190299) in vivo through rapid de-esterification in animals and man. AGN 190299 is capable of binding to all the three members of the retinoic acid receptor (RAR) family: RARα, RARβ, and RARγ with relative selectivity for RARβ, and RARγ. This process may further modify gene expression. However, it is unclear whether this is related to its mode of action. Common side effects associated with it include worsening of acne, desquamation, burning/stinging, erythema and pruritus increased sensitivity to sunlight, dry skin, itchiness, redness, skin pain rash and skin discoloration. In most cases, these side effects are mild and can remarkable decrease after the first 2–4 weeks. Tazarotene should not be used in the following cases: patients are allergic to it; patients are pregnant; patients have a sunburn; patients are taking photo-sensitive drugs such as thiazides and tetracycline.

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