Saroglitazar
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- $396 - $2760
- Product name: Saroglitazar
- CAS: 495399-09-2
- MF: C25H29NO4S
- MW: 439.57
- EINECS:
- MDL Number:MFCD28502034
- Synonyms:Saroglitazar;Benzenepropanoic acid, α-ethoxy-4-[2-[2-methyl-5-[4-(methylthio)phenyl]-1H-pyrrol-1-yl]ethoxy]-, (αS)-;(S)-2-Ethoxy-3-(4-(2-(2-methyl-5-(4-(methylthio)phenyl)-1H-pyrrol-1-yl)ethoxy)phenyl)propanoic acid
14 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- TRC
Package
- 2.5mg
- 5MG
- 10mg
- 25mg
- 50mg
- 100MG
- ManufacturerAK Scientific
- Product number8520DP
- Product descriptionSaroglitazar
- Packaging2.5mg
- Price$538
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0026335
- Product description(S)-2-ETHOXY-3-(4-(2-(2-METHYL-5-(4-(METHYLTHIO)PHENYL)-1H-PYRROL-1-YL)ETHOXY)PHENYL)PROPANOIC ACID 95.00%
- Packaging5MG
- Price$427.25
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0026335
- Product description(S)-2-ETHOXY-3-(4-(2-(2-METHYL-5-(4-(METHYLTHIO)PHENYL)-1H-PYRROL-1-YL)ETHOXY)PHENYL)PROPANOIC ACID 95.00%
- Packaging100MG
- Price$947
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number27851
- Product descriptionSaroglitazar
- Packaging2.5mg
- Price$396
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-6149
- Product descriptionSaroglitazar 98.03%
- Packaging5mg
- Price$396
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6149
- Product descriptionSaroglitazar 98.03%
- Packaging10mg
- Price$600
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6149
- Product descriptionSaroglitazar 98.03%
- Packaging25mg
- Price$1320
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6149
- Product descriptionSaroglitazar 98.03%
- Packaging50mg
- Price$1920
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6149
- Product descriptionSaroglitazar 98.03%
- Packaging100mg
- Price$2760
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11116780
- Product descriptionSaroglitazar 97%
- Packaging5mg
- Price$558
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11116780
- Product descriptionSaroglitazar 97%
- Packaging10mg
- Price$812
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10322
- Product descriptionSaroglitazar >98%
- Packaging100mg
- Price$1100
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number61682
- Product descriptionSaroglitazar
- Packaging2.5mg
- Price$675
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberS141650
- Product descriptionSaroglitazar
- Packaging25mg
- Price$1390
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8520DP | Saroglitazar | 2.5mg | $538 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0026335 | (S)-2-ETHOXY-3-(4-(2-(2-METHYL-5-(4-(METHYLTHIO)PHENYL)-1H-PYRROL-1-YL)ETHOXY)PHENYL)PROPANOIC ACID 95.00% | 5MG | $427.25 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0026335 | (S)-2-ETHOXY-3-(4-(2-(2-METHYL-5-(4-(METHYLTHIO)PHENYL)-1H-PYRROL-1-YL)ETHOXY)PHENYL)PROPANOIC ACID 95.00% | 100MG | $947 | 2021-12-16 | Buy |
| Cayman Chemical | 27851 | Saroglitazar | 2.5mg | $396 | 2024-03-01 | Buy |
| ChemScene | CS-6149 | Saroglitazar 98.03% | 5mg | $396 | 2021-12-16 | Buy |
| ChemScene | CS-6149 | Saroglitazar 98.03% | 10mg | $600 | 2021-12-16 | Buy |
| ChemScene | CS-6149 | Saroglitazar 98.03% | 25mg | $1320 | 2021-12-16 | Buy |
| ChemScene | CS-6149 | Saroglitazar 98.03% | 50mg | $1920 | 2021-12-16 | Buy |
| ChemScene | CS-6149 | Saroglitazar 98.03% | 100mg | $2760 | 2021-12-16 | Buy |
| Crysdot | CD11116780 | Saroglitazar 97% | 5mg | $558 | 2021-12-16 | Buy |
| Crysdot | CD11116780 | Saroglitazar 97% | 10mg | $812 | 2021-12-16 | Buy |
| DC Chemicals | DC10322 | Saroglitazar >98% | 100mg | $1100 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 61682 | Saroglitazar | 2.5mg | $675 | 2021-12-16 | Buy |
| TRC | S141650 | Saroglitazar | 25mg | $1390 | 2021-12-16 | Buy |
Properties
Boiling point :621.0±55.0 °C(Predicted)
Density :1.15±0.1 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form :Gel
pka :3.60±0.10(Predicted)
color :Red
Density :1.15±0.1 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form :Gel
pka :3.60±0.10(Predicted)
color :Red
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Saroglitazar (also known as ZYH1) was approved for use by the Drug Controller General of India for the treatment of diabetic dyslipidemia and hypertriglyceridemia that is not controlled by statin therapy. Saroglitazar is the first approved agent with dual PPAR agonist activity, with EC50s of 0.00065 and 3 nM, respectively, for the α- and γ-PPAR isoforms in HepG2 cells. The medicinal chemistry program has not been described in the scientific literature, but numerous substituents on the pyrrole ring are described in the saroglitazar patent. These substituted pyrroles were synthesized via ethanolamine condensation with substituted diketones and subsequent activation of the hydroxyethylpyrrole for phenolic etherification with (S)-2- ethoxy-3-(4-hydroxyphenyl)propanoic acid. The efficacy of saroglitazar was evaluated in db/db mice (genetically diabetic animals that lack the leptin receptor), wherein it produced a 17–55% reduction in serum triglycerides (TGs) after 12 days of administration of saroglitazar (0.01–3 mg/kg).More related product prices
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