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ChemicalBook >> CAS DataBase List >> (R)-2-Flurbiprofen

(R)-2-Flurbiprofen

(R)-2-Flurbiprofen price.
  • $32 - $675
  • Product name: (R)-2-Flurbiprofen
  • CAS: 51543-40-9
  • MF: C15H13FO2
  • MW: 244.26
  • EINECS:257-264-7
  • MDL Number:MFCD00869714
  • Synonyms:(R)-2-Fluoro-α-methyl-1,1'-biphenyl-4-acetic acid;(R)-α-Methyl-2-fluoro-1,1'-biphenyl-4-acetic acid;(R)-(-)-2-Fluoro-alpha-methyl-4-biphenylacetic acid (Flurbiprofe;[1,1'-Biphenyl]-4-aceticacid, 2-fluoro-a-Methyl-,(aR)-;MPC 7869;(R)-(-)-2-Fluoro-alpha-methyl-4-biphenylacetic acid 97%;(R)-Flurbiprofen, >=99%;(R)-2-Flurbiprofenr
17 prices
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Brand
  • AHH
  • ApexBio Technology
  • AvaChem
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • Medical Isotopes, Inc.
  • TRC
  • Usbiological
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 5g
  • ManufacturerAHH
  • Product numberMT-23919
  • Product description(R)-2-Flubiprofen 97%
  • Packaging5g
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4402
  • Product descriptionFlurizan
  • Packaging50mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2619
  • Product description(R)-2-Flurbiprofen
  • Packaging10mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2619
  • Product description(R)-2-Flurbiprofen
  • Packaging100mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2619
  • Product description(R)-2-Flurbiprofen
  • Packaging1g
  • Price$290
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number70255
  • Product description(R)-Flurbiprofen ≥99%
  • Packaging100mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number70255
  • Product description(R)-Flurbiprofen ≥99%
  • Packaging250mg
  • Price$73
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number70255
  • Product description(R)-Flurbiprofen ≥99%
  • Packaging500mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number70255
  • Product description(R)-Flurbiprofen ≥99%
  • Packaging1g
  • Price$133
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6056
  • Product descriptionTarenflurbil 99.99%
  • Packaging100mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31001671
  • Product description(R)-Flurbiprofen 95+%
  • Packaging1g
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31001671
  • Product description(R)-Flurbiprofen 95+%
  • Packaging5mg
  • Price$86
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN12719
  • Product description(R)-Flurbiprofen
  • Packaging25mg
  • Price$35
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN12719
  • Product description(R)-Flurbiprofen
  • Packaging100mg
  • Price$48
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number58248
  • Product description(R)-2-Flurbiprofen
  • Packaging1g
  • Price$675
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberF598730
  • Product description(R)-Flurbiprofen
  • Packaging250mg
  • Price$140
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-23919 (R)-2-Flubiprofen 97% 5g $250 2021-12-16 Buy
ApexBio Technology A4402 Flurizan 50mg $45 2021-12-16 Buy
AvaChem 2619 (R)-2-Flurbiprofen 10mg $119 2021-12-16 Buy
AvaChem 2619 (R)-2-Flurbiprofen 100mg $189 2021-12-16 Buy
AvaChem 2619 (R)-2-Flurbiprofen 1g $290 2021-12-16 Buy
Cayman Chemical 70255 (R)-Flurbiprofen ≥99% 100mg $32 2024-03-01 Buy
Cayman Chemical 70255 (R)-Flurbiprofen ≥99% 250mg $73 2024-03-01 Buy
Cayman Chemical 70255 (R)-Flurbiprofen ≥99% 500mg $116 2024-03-01 Buy
Cayman Chemical 70255 (R)-Flurbiprofen ≥99% 1g $133 2024-03-01 Buy
ChemScene CS-6056 Tarenflurbil 99.99% 100mg $60 2021-12-16 Buy
Crysdot CD31001671 (R)-Flurbiprofen 95+% 1g $200 2021-12-16 Buy
Crysdot CD31001671 (R)-Flurbiprofen 95+% 5mg $86 2021-12-16 Buy
CSNpharm CSN12719 (R)-Flurbiprofen 25mg $35 2021-12-16 Buy
CSNpharm CSN12719 (R)-Flurbiprofen 100mg $48 2021-12-16 Buy
Medical Isotopes, Inc. 58248 (R)-2-Flurbiprofen 1g $675 2021-12-16 Buy
TRC F598730 (R)-Flurbiprofen 250mg $140 2021-12-16 Buy

Properties

Melting point :110-113 °C(lit.)
Boiling point :376.2±30.0 °C(Predicted)
Density :1.199±0.06 g/cm3(Predicted)
storage temp. :Store at RT
solubility :DMF: 25 mg/ml; DMSO: 10 mg/ml; Ethanol: 25 mg/ml; PBS (pH 7.2): .9 mg/ml
pka :4.14±0.10(Predicted)
form :Crystalline Powder
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

(R)-Flurbiprofen is a member of the 2-aryl propionic acid group of nonsteroidal anti-inflammatory drugs (NSAIDs). Only a small amount (<5%) of (R)-enantiomer is converted to the (S)-enantiomer in rats and humans; therefore, the biological effects are specific to each enantiomer. Although inactive as an inhibitor of cyclooxygenase (COX), this enantiomer reduces inflammation through inhibition of NF-κB and AP-1 activation. (R)-Flurbiprofen has also been shown to suppress prostate tumor cells by inducing p75NTR protein expression. (R)-Flurbiprofen inhibits the enzyme γ-secretase thereby preventing the formation of the amyloid β peptide (Aβ42) from amyloid β precursor protein (APP). Before being dropped as a drug candidate, (R)-flurbiprofen advanced to Phase III clinical trials, the first drug candidate to advance to late stage trials for the treatment of mild Alzheimer’s disease.