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ChemicalBook >> CAS DataBase List >> PHORBOL 12,13-DIBUTYRATE

PHORBOL 12,13-DIBUTYRATE

PHORBOL 12,13-DIBUTYRATE price.
  • $75 - $1040
  • Product name: PHORBOL 12,13-DIBUTYRATE
  • CAS: 37558-16-0
  • MF: C28H40O8
  • MW: 504.61
  • EINECS:
  • MDL Number:MFCD00036783
  • Synonyms:butanoicacid,1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-3-(hydroxymet ;hyl)-1,1,6,8-tetramethyl-5-oxo-9ah-cyclopropa(3,4)benz(1,2-e)azulene-9,9a-diy ;lester,(1ar-(1a-alpha,1b-beta,4a-beta,7a-alpha,7b-alpha,8-alpha,9-beta,9a-al ;PDBU;PHORBOL 12,13-DIBUTYRATE;PHORBOL 12,13-DIBUTYRATE, 4BETA;(1aR)-1,1aα,1bβ,4,4a,7aα,7b,8,9,9a-Decahydro-4aβ,7bα-dihydroxy-3-hydroxymethyl-1,1,6,8α-tetramethyl-5-oxo-5H-cyclopropa[3,4]benz[1,2-e]azulene-9β,9aα-diol 9,9a-dibutyrate;9β,9aα-Bis(butyryloxy)-1,1aα,1bβ,4,4a,7aα,7b,8,9,9a-decahydro-4aβ,7bα-dihydroxy-3-(hydroxymethyl)-1,1,6,8α-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one
20 prices
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Brand
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • Usbiological
Package
  • 1
  • 1MG
  • 5mg
  • 10mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001282
  • Product descriptionPHORBOL 12,13-DIBUTYRATE 95.00%
  • Packaging1MG
  • Price$664.82
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIP1016
  • Product descriptionPhorbol 12,13-dibutyrate >99%
  • Packaging1mg
  • Price$109
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIP1016
  • Product descriptionPhorbol 12,13-dibutyrate >99%
  • Packaging5mg
  • Price$327
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIP1016
  • Product descriptionPhorbol 12,13-dibutyrate >99%
  • Packaging10mg
  • Price$544
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb61079
  • Product descriptionPhorbol 12,13-Dibutyrate >99% pure
  • Packaging1mg
  • Price$297.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb61079
  • Product descriptionPhorbol 12,13-Dibutyrate >99% pure
  • Packaging5mg
  • Price$470.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb61079
  • Product descriptionPhorbol 12,13-Dibutyrate >99% pure
  • Packaging10mg
  • Price$566.1
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number27785
  • Product descriptionPhorbol 12,13-dibutyrate
  • Packaging1mg
  • Price$79
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number27785
  • Product descriptionPhorbol 12,13-dibutyrate
  • Packaging5mg
  • Price$254
  • Updated2024-03-01
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  • ManufacturerChemScene
  • Product numberCS-0014826
  • Product descriptionPhorbol 12,13-dibutyrate 98.92%
  • Packaging5mg
  • Price$210
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0014826
  • Product descriptionPhorbol 12,13-dibutyrate 98.92%
  • Packaging10mg
  • Price$370
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number74791
  • Product descriptionPhorbol 12,13-dibutyrate >99%
  • Packaging5mg
  • Price$1040
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number524390
  • Product descriptionPhorbol-12,13-dibutyrate
  • Packaging1mg
  • Price$99.4
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberP1269
  • Product descriptionPhorbol 12,13-dibutyrate ≥98% (TLC), powder
  • Packaging1mg
  • Price$107
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberP1269
  • Product descriptionPhorbol 12,13-dibutyrate ≥98% (TLC), powder
  • Packaging10mg
  • Price$253.6
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number524390
  • Product descriptionPhorbol-12,13-dibutyrate
  • Packaging5mg
  • Price$289
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation KIN0001282 PHORBOL 12,13-DIBUTYRATE 95.00% 1MG $664.82 2021-12-16 Buy
Apolloscientific BIP1016 Phorbol 12,13-dibutyrate >99% 1mg $109 2021-12-16 Buy
Apolloscientific BIP1016 Phorbol 12,13-dibutyrate >99% 5mg $327 2021-12-16 Buy
Apolloscientific BIP1016 Phorbol 12,13-dibutyrate >99% 10mg $544 2021-12-16 Buy
Biorbyt Ltd orb61079 Phorbol 12,13-Dibutyrate >99% pure 1mg $297.5 2021-12-16 Buy
Biorbyt Ltd orb61079 Phorbol 12,13-Dibutyrate >99% pure 5mg $470.9 2021-12-16 Buy
Biorbyt Ltd orb61079 Phorbol 12,13-Dibutyrate >99% pure 10mg $566.1 2021-12-16 Buy
Cayman Chemical 27785 Phorbol 12,13-dibutyrate 1mg $79 2024-03-01 Buy
Cayman Chemical 27785 Phorbol 12,13-dibutyrate 5mg $254 2024-03-01 Buy
ChemScene CS-0014826 Phorbol 12,13-dibutyrate 98.92% 5mg $210 2021-12-16 Buy
ChemScene CS-0014826 Phorbol 12,13-dibutyrate 98.92% 10mg $370 2021-12-16 Buy
Medical Isotopes, Inc. 74791 Phorbol 12,13-dibutyrate >99% 5mg $1040 2021-12-16 Buy
Sigma-Aldrich 524390 Phorbol-12,13-dibutyrate 1mg $99.4 2024-03-01 Buy
Sigma-Aldrich P1269 Phorbol 12,13-dibutyrate ≥98% (TLC), powder 1mg $107 2024-03-01 Buy
Sigma-Aldrich P1269 Phorbol 12,13-dibutyrate ≥98% (TLC), powder 10mg $253.6 2024-03-01 Buy
Sigma-Aldrich 524390 Phorbol-12,13-dibutyrate 5mg $289 2024-03-01 Buy

Properties

Boiling point :513.95°C (rough estimate)
Density :1.1270 (rough estimate)
refractive index :1.4480 (estimate)
storage temp. :-20°C
solubility :H2O: 30 μM
pka :11.15±0.70(Predicted)
form :powder
color :clear, light yellow, film
BRN :6551234
CAS DataBase Reference :37558-16-0(CAS DataBase Reference)
EPA Substance Registry System :Phorbol 12,13-dibutyrate (37558-16-0)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Phorbol-12,13-dibutyrate is a strong irritant for mouse skin, but only moderately active as a tumor promoter. This compound activates protein kinase C. Phorbol-12,13-dibutyrate stimulates the phosphorylation of Na+,K+- ATPase, thereby inhibiting its activity. Promotes the expression of inducible NOS in cultured hepatocytes. Phorbol-12,13-dibutyrate is commonly used in binding studies or in applications requiring high concentrations of phorbol compounds.

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