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ChemicalBook >> CAS DataBase List >> PAXILLINE

PAXILLINE

PAXILLINE price.
  • $45 - $1600
  • Product name: PAXILLINE
  • CAS: 57186-25-1
  • MF: C27H33NO4
  • MW: 435.56
  • EINECS:637-206-0
  • MDL Number:MFCD00083464
  • Synonyms:(2R)-5,6,6aα,7,12,12b,12c,13,14,14aβ-Decahydro-4bβ-hydroxy-2-(1-hydroxy-1-methylethyl)-12bβ,12cα-dimethyl-2H-1-benzopyrano[5',6':6,7]indeno[1,2-b]indol-3(4bH)-one;2h-1-benzopyrano(5’,6’:6,7)indeno(1,2-b)indol-3(4bh)-one,5,6,6a,7,12,12b,12c,1 ;4b-beta,6a-alpha,12b-beta,12c-alpha,14a-beta)-2-alph ;paxilline from penicillium paxilli;PAXILINE;Paxicillin;(2R,4bS,6aS,12bS,12cR,14aS)-4b-Hydroxy-2-(1-hydroxy-1-methylethyl)-12b,12c-dimethyl-5,6,6a,7,12,12b,12c,13,14,14a-decahydro-2H-chromeno[5′,6′:6,7]indeno[1,2-b]indol-3(4bH)-one solution;Paxilline solution
19 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • Alfa Aesar
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 5mg
  • 10
  • 1mg
  • 10mg
  • 0.01g
  • 25mg
  • 50mg
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0167-M005
  • Product descriptionPaxilline ≥95%(HPLC)
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-57661
  • Product descriptionPaxilline 98%
  • Packaging0.01g
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number8972AJ
  • Product descriptionPaxilline
  • Packaging5mg
  • Price$233
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61341
  • Product descriptionPaxilline, 97+%
  • Packaging5mg
  • Price$216.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61341
  • Product descriptionPaxilline, 97+%
  • Packaging25mg
  • Price$639
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6920
  • Product descriptionPaxilline
  • Packaging5mg
  • Price$138
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6920
  • Product descriptionPaxilline
  • Packaging10mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11345
  • Product descriptionPaxilline ≥98%
  • Packaging1mg
  • Price$45
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11345
  • Product descriptionPaxilline ≥98%
  • Packaging5mg
  • Price$121
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11345
  • Product descriptionPaxilline ≥98%
  • Packaging10mg
  • Price$220
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0026740
  • Product descriptionPaxilline 99.70%
  • Packaging5mg
  • Price$380
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0026740
  • Product descriptionPaxilline 99.70%
  • Packaging10mg
  • Price$630
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0026740
  • Product descriptionPaxilline 99.70%
  • Packaging50mg
  • Price$1600
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberP2928
  • Product descriptionPaxilline powder, ≥98% (HPLC)
  • Packaging5mg
  • Price$414
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberP2928
  • Product descriptionPaxilline powder, ≥98% (HPLC)
  • Packaging10mg
  • Price$762
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number2006
  • Product descriptionPaxilline ≥98%(HPLC)
  • Packaging10
  • Price$296
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CN2-0167-M005 Paxilline ≥95%(HPLC) 5mg $120 2021-12-16 Buy
AHH MT-57661 Paxilline 98% 0.01g $230 2021-12-16 Buy
AK Scientific 8972AJ Paxilline 5mg $233 2021-12-16 Buy
Alfa Aesar J61341 Paxilline, 97+% 5mg $216.65 2024-03-01 Buy
Alfa Aesar J61341 Paxilline, 97+% 25mg $639 2021-12-16 Buy
ApexBio Technology B6920 Paxilline 5mg $138 2021-12-16 Buy
ApexBio Technology B6920 Paxilline 10mg $250 2021-12-16 Buy
Cayman Chemical 11345 Paxilline ≥98% 1mg $45 2024-03-01 Buy
Cayman Chemical 11345 Paxilline ≥98% 5mg $121 2024-03-01 Buy
Cayman Chemical 11345 Paxilline ≥98% 10mg $220 2024-03-01 Buy
ChemScene CS-0026740 Paxilline 99.70% 5mg $380 2021-12-16 Buy
ChemScene CS-0026740 Paxilline 99.70% 10mg $630 2021-12-16 Buy
ChemScene CS-0026740 Paxilline 99.70% 50mg $1600 2021-12-16 Buy
Sigma-Aldrich P2928 Paxilline powder, ≥98% (HPLC) 5mg $414 2024-03-01 Buy
Sigma-Aldrich P2928 Paxilline powder, ≥98% (HPLC) 10mg $762 2024-03-01 Buy
Tocris 2006 Paxilline ≥98%(HPLC) 10 $296 2021-12-16 Buy

Properties

Flash point :2℃
storage temp. :2-8°C
solubility :Soluble in DMSO, acetone or chloroform.
form :powder
color :faint yellow

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Paxilline is an indole diterpene from fungi which potently and reversibly inhibits large conductance Ca2+-activated K+ (BKCa) channels, as shown in patch clamp (Ki = 1.9 nM) and whole smooth muscle cell studies (Ki = 35.7 nM). It also enhances the binding of charybdotoxin, a peptidyl neurotoxin, to BKCa channels. Paxilline is currently used to evaluate the role of BKCa channels in various cell processes and responses.

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