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ChemicalBook >> CAS DataBase List >> Norfloxacin

Norfloxacin

Norfloxacin price.
  • $5 - $957.1
  • Product name: Norfloxacin
  • CAS: 70458-96-7
  • MF: C16H18FN3O3
  • MW: 319.33
  • EINECS:274-614-4
  • MDL Number:MFCD00079532
  • Synonyms:Zoroxin;NORFLOXACINUM;Norfloxacin (base and/or unspecified salts);1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid;4803P;MK-0366;Norfloxacin(Nicotinate&Hcl);1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino-3-quinolinecarboxylic acid, 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
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  • ManufacturerAHH
  • Product numberAPI-1097
  • Product descriptionNorfloxacine 98%
  • Packaging100g
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ95738
  • Product descriptionNorfloxacin
  • Packaging1g
  • Price$10
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberG162
  • Product descriptionNorfloxacin
  • Packaging25g
  • Price$81
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberG162
  • Product descriptionNorfloxacin
  • Packaging100g
  • Price$261
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ62652
  • Product descriptionNorfloxacin
  • Packaging1g
  • Price$24.4
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ62652
  • Product descriptionNorfloxacin
  • Packaging5g
  • Price$64.2
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberJ62652
  • Product descriptionNorfloxacin
  • Packaging25g
  • Price$186
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA165613
  • Product description1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylicacid 98+%
  • Packaging50mg
  • Price$5
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA165613
  • Product description1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylicacid 98+%
  • Packaging5g
  • Price$6
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA165613
  • Product description1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylicacid 98+%
  • Packaging10g
  • Price$9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA165613
  • Product description1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylicacid 98+%
  • Packaging25g
  • Price$20
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA165613
  • Product description1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylicacid 98+%
  • Packaging100g
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA165613
  • Product description1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylicacid 98+%
  • Packaging500g
  • Price$213
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1801
  • Product descriptionNorfloxacin
  • Packaging10g
  • Price$90
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS025530
  • Product descriptionNorfloxacin ≥98%
  • Packaging5g
  • Price$6
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS025530
  • Product descriptionNorfloxacin ≥98%
  • Packaging10g
  • Price$9
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1097 Norfloxacine 98% 100g $190 2021-12-16 Buy
AK Scientific J95738 Norfloxacin 1g $10 2021-12-16 Buy
AK Scientific G162 Norfloxacin 25g $81 2021-12-16 Buy
AK Scientific G162 Norfloxacin 100g $261 2021-12-16 Buy
Alfa Aesar J62652 Norfloxacin 1g $24.4 2024-03-01 Buy
Alfa Aesar J62652 Norfloxacin 5g $64.2 2024-03-01 Buy
Alfa Aesar J62652 Norfloxacin 25g $186 2024-03-01 Buy
Ambeed A165613 1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylicacid 98+% 50mg $5 2021-12-16 Buy
Ambeed A165613 1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylicacid 98+% 5g $6 2021-12-16 Buy
Ambeed A165613 1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylicacid 98+% 10g $9 2021-12-16 Buy
Ambeed A165613 1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylicacid 98+% 25g $20 2021-12-16 Buy
Ambeed A165613 1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylicacid 98+% 100g $55 2021-12-16 Buy
Ambeed A165613 1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylicacid 98+% 500g $213 2021-12-16 Buy
ApexBio Technology B1801 Norfloxacin 10g $90 2021-12-16 Buy
Arctom AS025530 Norfloxacin ≥98% 5g $6 2021-12-16 Buy
Arctom AS025530 Norfloxacin ≥98% 10g $9 2021-12-16 Buy

Properties

Melting point :220°C
Boiling point :555.8±50.0 °C(Predicted)
Density :1.2504 (estimate)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :Very slightly soluble in water, slightly soluble in acetone and in ethanol (96 per cent).
form :Crystalline Powder
pka :pKa1 6.34; pKa2 8.75(at 25℃)
color :White to yellow
Water Solubility :Soluble in acetic acid. Also soluble in acetone or cloroform. Slightly soluble in water
Merck :14,6700
Stability :Hygroscopic
InChI :InChI=1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)
InChIKey :OGJPXUAPXNRGGI-UHFFFAOYSA-N
SMILES :N1(CC)C2=C(C=C(F)C(N3CCNCC3)=C2)C(=O)C(C(O)=O)=C1
CAS DataBase Reference :70458-96-7(CAS DataBase Reference)
EPA Substance Registry System :3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)- (70458-96-7)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

It finds it application as a fluorinated quinolone antibacterial. It is clinically used to treat urinary tract infections and prostatitis. In neutrophils from cirrhotic subjects, norfloxacin increases expression of IL-10 and heme oxygenase 1 (HO-1) and decreases expression of pro-inflammatory cytokines. Additionally, when complexed with gold(III), norfloxacin binds DNA and inhibits cellular proliferation in several cancer cell lines.

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