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ChemicalBook >> CAS DataBase List >> Miltefosine

Miltefosine

Miltefosine price.
  • $30 - $2143.23
  • Product name: Miltefosine
  • CAS: 58066-85-6
  • MF: C21H46NO4P
  • MW: 407.57
  • EINECS:622-572-6
  • MDL Number:MFCD00133396
  • Synonyms:2-(((hexadecyloxy)hydroxyphosphinyl)oxy)-n,n,n-trimethyl-ethanaminiuhydrox ;2-(((hexadecyloxy)hydroxyphosphinyl)oxy)-n,n,n-trimethylethanaminiumhydroxid ;cholinephosphate,hexadecylester,hydroxide,innersalt ;d18506 ;Hexadecyl 2-(trimethylamino)ethyl phosphate;Miltex;13-18506;2-[[(Hexadecyloxy)hydroxyphasphinyl]oxy]-N,N,N-trimethylethanaminiminner salt
37 prices
Selected condition:
Brand
  • AHH
  • AK Scientific
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • Axon Medchem
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 5mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 10mM(in 1mL H2O)
  • 500mg
  • 1g
  • 2.5g
  • 5g
  • 25G
  • 50g
  • ManufacturerAHH
  • Product numberMT-54305
  • Product descriptionMiltefosine 98%
  • Packaging50g
  • Price$730
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberC786
  • Product descriptionMiltefosine
  • Packaging100mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1371
  • Product descriptionMiltefosine
  • Packaging50mg
  • Price$42
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1371
  • Product descriptionMiltefosine
  • Packaging10mM(in 1mL H2O)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1371
  • Product descriptionMiltefosine
  • Packaging100mg
  • Price$63
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1371
  • Product descriptionMiltefosine
  • Packaging500mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIB6120
  • Product descriptionHexadecylphosphocholine
  • Packaging250mg
  • Price$51
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIB6120
  • Product descriptionHexadecylphosphocholine
  • Packaging1g
  • Price$138
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIB6120
  • Product descriptionHexadecylphosphocholine
  • Packaging2.5g
  • Price$276
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS030016
  • Product descriptionMiltefosine ≥98%
  • Packaging250mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS030016
  • Product descriptionMiltefosine ≥98%
  • Packaging1g
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS030016
  • Product descriptionMiltefosine ≥98%
  • Packaging5g
  • Price$288
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon3247
  • Product descriptionMiltefosine-Hexadecylphosphocholine|HPC|HePC 98%
  • Packaging50mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number63280
  • Product descriptionMiltefosine ≥98%
  • Packaging50mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number63280
  • Product descriptionMiltefosine ≥98%
  • Packaging100mg
  • Price$50
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number63280
  • Product descriptionMiltefosine ≥98%
  • Packaging500mg
  • Price$122
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-54305 Miltefosine 98% 50g $730 2021-12-16 Buy
AK Scientific C786 Miltefosine 100mg $140 2021-12-16 Buy
ApexBio Technology B1371 Miltefosine 50mg $42 2021-12-16 Buy
ApexBio Technology B1371 Miltefosine 10mM(in 1mL H2O) $50 2021-12-16 Buy
ApexBio Technology B1371 Miltefosine 100mg $63 2021-12-16 Buy
ApexBio Technology B1371 Miltefosine 500mg $133 2021-12-16 Buy
Apolloscientific BIB6120 Hexadecylphosphocholine 250mg $51 2021-12-16 Buy
Apolloscientific BIB6120 Hexadecylphosphocholine 1g $138 2021-12-16 Buy
Apolloscientific BIB6120 Hexadecylphosphocholine 2.5g $276 2021-12-16 Buy
Arctom AS030016 Miltefosine ≥98% 250mg $30 2021-12-16 Buy
Arctom AS030016 Miltefosine ≥98% 1g $72 2021-12-16 Buy
Arctom AS030016 Miltefosine ≥98% 5g $288 2021-12-16 Buy
Axon Medchem Axon3247 Miltefosine-Hexadecylphosphocholine|HPC|HePC 98% 50mg $55 2021-12-16 Buy
Cayman Chemical 63280 Miltefosine ≥98% 50mg $32 2024-03-01 Buy
Cayman Chemical 63280 Miltefosine ≥98% 100mg $50 2024-03-01 Buy
Cayman Chemical 63280 Miltefosine ≥98% 500mg $122 2024-03-01 Buy

Properties

Melting point :232-234° (dec)
storage temp. :room temp
solubility :H2O: soluble10mg/mL, clear, colorless
form :Crystalline solid
color :White to Almost white
InChI :InChI=1S/C21H46NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-25-27(23,24)26-21-19-22(2,3)4/h5-21H2,1-4H3
InChIKey :PQLXHQMOHUQAKB-UHFFFAOYSA-N
SMILES :O(CCCCCCCCCCCCCCCC)P([O-])(=O)OCC[N+](C)(C)C
CAS DataBase Reference :58066-85-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Miltefosine is an inhibitor of CTP:phosphocholine cytidylyl transferase and has antimetastatic properties. At concentrations of 3 and 25 μM, miltefosine inhibits proliferation of HaCaT cells (immortalized human keratinocyte cell line) by 50% and 94%, respectively. The mechanism of action of miltefosine is not well established, but the antiproliferative effect may be mediated by an increase in cellular ceramide which results in apoptosis. Treatment of cells with 25 μM miltefosine results in a 53% increase in ceramide concentration relative to control. Miltefosine is more than 90% effective in eradicating visceral infections of Leishmania species (kala azar), although the mechanism of this antiprotozoal activity is also poorly understood.

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