Miltefosine
- $30 - $2143.23
- Product name: Miltefosine
- CAS: 58066-85-6
- MF: C21H46NO4P
- MW: 407.57
- EINECS:622-572-6
- MDL Number:MFCD00133396
- Synonyms:2-(((hexadecyloxy)hydroxyphosphinyl)oxy)-n,n,n-trimethyl-ethanaminiuhydrox ;2-(((hexadecyloxy)hydroxyphosphinyl)oxy)-n,n,n-trimethylethanaminiumhydroxid ;cholinephosphate,hexadecylester,hydroxide,innersalt ;d18506 ;Hexadecyl 2-(trimethylamino)ethyl phosphate;Miltex;13-18506;2-[[(Hexadecyloxy)hydroxyphasphinyl]oxy]-N,N,N-trimethylethanaminiminner salt
37 prices
Selected condition:
Brand
- AHH
- AK Scientific
- ApexBio Technology
- Apolloscientific
- Arctom
- Axon Medchem
- Cayman Chemical
- Chem-Impex
- ChemScene
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 5mg
- 25mg
- 50mg
- 100mg
- 250mg
- 10mM(in 1mL H2O)
- 500mg
- 1g
- 2.5g
- 5g
- 25G
- 50g
- ManufacturerAHH
- Product numberMT-54305
- Product descriptionMiltefosine 98%
- Packaging50g
- Price$730
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberC786
- Product descriptionMiltefosine
- Packaging100mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1371
- Product descriptionMiltefosine
- Packaging50mg
- Price$42
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1371
- Product descriptionMiltefosine
- Packaging10mM(in 1mL H2O)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1371
- Product descriptionMiltefosine
- Packaging100mg
- Price$63
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1371
- Product descriptionMiltefosine
- Packaging500mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIB6120
- Product descriptionHexadecylphosphocholine
- Packaging250mg
- Price$51
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIB6120
- Product descriptionHexadecylphosphocholine
- Packaging1g
- Price$138
- Updated2021-12-16
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- ManufacturerApolloscientific
- Product numberBIB6120
- Product descriptionHexadecylphosphocholine
- Packaging2.5g
- Price$276
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS030016
- Product descriptionMiltefosine ≥98%
- Packaging250mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS030016
- Product descriptionMiltefosine ≥98%
- Packaging1g
- Price$72
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS030016
- Product descriptionMiltefosine ≥98%
- Packaging5g
- Price$288
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon3247
- Product descriptionMiltefosine-Hexadecylphosphocholine|HPC|HePC 98%
- Packaging50mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number63280
- Product descriptionMiltefosine ≥98%
- Packaging50mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number63280
- Product descriptionMiltefosine ≥98%
- Packaging100mg
- Price$50
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number63280
- Product descriptionMiltefosine ≥98%
- Packaging500mg
- Price$122
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AHH | MT-54305 | Miltefosine 98% | 50g | $730 | 2021-12-16 | Buy |
AK Scientific | C786 | Miltefosine | 100mg | $140 | 2021-12-16 | Buy |
ApexBio Technology | B1371 | Miltefosine | 50mg | $42 | 2021-12-16 | Buy |
ApexBio Technology | B1371 | Miltefosine | 10mM(in 1mL H2O) | $50 | 2021-12-16 | Buy |
ApexBio Technology | B1371 | Miltefosine | 100mg | $63 | 2021-12-16 | Buy |
ApexBio Technology | B1371 | Miltefosine | 500mg | $133 | 2021-12-16 | Buy |
Apolloscientific | BIB6120 | Hexadecylphosphocholine | 250mg | $51 | 2021-12-16 | Buy |
Apolloscientific | BIB6120 | Hexadecylphosphocholine | 1g | $138 | 2021-12-16 | Buy |
Apolloscientific | BIB6120 | Hexadecylphosphocholine | 2.5g | $276 | 2021-12-16 | Buy |
Arctom | AS030016 | Miltefosine ≥98% | 250mg | $30 | 2021-12-16 | Buy |
Arctom | AS030016 | Miltefosine ≥98% | 1g | $72 | 2021-12-16 | Buy |
Arctom | AS030016 | Miltefosine ≥98% | 5g | $288 | 2021-12-16 | Buy |
Axon Medchem | Axon3247 | Miltefosine-Hexadecylphosphocholine|HPC|HePC 98% | 50mg | $55 | 2021-12-16 | Buy |
Cayman Chemical | 63280 | Miltefosine ≥98% | 50mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 63280 | Miltefosine ≥98% | 100mg | $50 | 2024-03-01 | Buy |
Cayman Chemical | 63280 | Miltefosine ≥98% | 500mg | $122 | 2024-03-01 | Buy |
Properties
Melting point :232-234° (dec)
storage temp. :room temp
solubility :H2O: soluble10mg/mL, clear, colorless
form :Crystalline solid
color :White to Almost white
InChI :InChI=1S/C21H46NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-25-27(23,24)26-21-19-22(2,3)4/h5-21H2,1-4H3
InChIKey :PQLXHQMOHUQAKB-UHFFFAOYSA-N
SMILES :O(CCCCCCCCCCCCCCCC)P([O-])(=O)OCC[N+](C)(C)C
CAS DataBase Reference :58066-85-6(CAS DataBase Reference)
storage temp. :room temp
solubility :H2O: soluble10mg/mL, clear, colorless
form :Crystalline solid
color :White to Almost white
InChI :InChI=1S/C21H46NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-25-27(23,24)26-21-19-22(2,3)4/h5-21H2,1-4H3
InChIKey :PQLXHQMOHUQAKB-UHFFFAOYSA-N
SMILES :O(CCCCCCCCCCCCCCCC)P([O-])(=O)OCC[N+](C)(C)C
CAS DataBase Reference :58066-85-6(CAS DataBase Reference)
Safety Information
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Signal word: | Danger | ||||||||||||||
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Description
Miltefosine is an inhibitor of CTP:phosphocholine cytidylyl transferase and has antimetastatic properties. At concentrations of 3 and 25 μM, miltefosine inhibits proliferation of HaCaT cells (immortalized human keratinocyte cell line) by 50% and 94%, respectively. The mechanism of action of miltefosine is not well established, but the antiproliferative effect may be mediated by an increase in cellular ceramide which results in apoptosis. Treatment of cells with 25 μM miltefosine results in a 53% increase in ceramide concentration relative to control. Miltefosine is more than 90% effective in eradicating visceral infections of Leishmania species (kala azar), although the mechanism of this antiprotozoal activity is also poorly understood.Related product price
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Suppliers and manufacturers
Beijing Mesochem Technology Co.,Ltd
Capot Chemical Co.,Ltd.
Henan Tianfu Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
SHANDONG ZHI SHANG CHEMICAL CO.LTD