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ChemicalBook >> CAS DataBase List >> METHOTREXATE HYDRATE

METHOTREXATE HYDRATE

METHOTREXATE HYDRATE price.
  • $10 - $1370
  • Product name: METHOTREXATE HYDRATE
  • CAS: 133073-73-1
  • MF: C20H24N8O6
  • MW: 472.46
  • EINECS:625-397-3
  • MDL Number:MFCD00150847
  • Synonyms:l-4-amino-n10-methylpteroylglutamic acid;4-Amino-10-methylfolic acid hydrate, Antifolan hydrate, Methotrexate hydrate, Methylaminopterin hydrate, MTX hydrate, L-4-Amino-N10-methylpteroylglutamic acid hydrate;4-Amino-10-methylfolic acid hydrate, L-Amethopterin hydrate, Antifolan hydrate, Methylaminopterin hydrate, MTX hydrate, L-4-Amino-N10-methylpteroylglutamic acid hydrate;Methotrexate hydrate,4-Amino-10-methylfolic acid hydrate, L-4-Amino-N10-methylpteroylglutamic acid hydrate, L-Amethopterin hydrate, Antifolan hydrate, MTX hydrate, Methylaminopterin hydrate;Methotrexate hydrate,4-Amino-10-methylfolic acid hydrate, L-4-Amino-N10-methylpteroylglutamic acid hydrate, L-Amethopterin hydrate, Antifolan hydrate, MTX hydrate, Methotrexate hydrate, Methylaminopte;L(+)-AMethopterin hydrate, 99% 100MG;Methotrexate hydrate 4-AMino-10-Methylfolic acid hydrate;N-[4-[[(2,4-diaMino-6-pteridinyl)Methyl]MethylaMino]ben
47 prices
Selected condition:
Brand
  • Activate Scientific
  • AHH
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • BLDpharm
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100MG
  • 250mg
  • 0.5g
  • 500mg
  • 1g
  • 2g
  • 5g
  • 10g
  • 25g
  • 50g
  • ManufacturerActivate Scientific
  • Product numberAS110159-B
  • Product descriptionMethotrexate hydrate 99%
  • Packaging1g
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-16699
  • Product descriptionMethotrexate hydrate 98%
  • Packaging0.5g
  • Price$398
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberI965
  • Product descriptionL-Amethopterinhydrate
  • Packaging5g
  • Price$1023
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2504AH
  • Product descriptionMethotrexate hydrate
  • Packaging5g
  • Price$706
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ11212
  • Product descriptionMethotrexatedihydrate
  • Packaging5mg
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA575327
  • Product descriptionMethotrexatexhydrate 98%
  • Packaging250mg
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA575327
  • Product descriptionMethotrexatexhydrate 98%
  • Packaging1g
  • Price$19
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA575327
  • Product descriptionMethotrexatexhydrate 98%
  • Packaging5g
  • Price$63
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA575327
  • Product descriptionMethotrexatexhydrate 98%
  • Packaging25g
  • Price$218
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007745
  • Product descriptionMETHOTREXATE HYDRATE 95.00%
  • Packaging100MG
  • Price$622.13
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007745
  • Product descriptionMETHOTREXATE HYDRATE 95.00%
  • Packaging1G
  • Price$708.31
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007745
  • Product descriptionMETHOTREXATE HYDRATE 95.00%
  • Packaging5G
  • Price$1144.84
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA32143
  • Product descriptionL(+)-Amethopterin hydrate
  • Packaging2g
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA32143
  • Product descriptionL(+)-Amethopterin hydrate
  • Packaging5G
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA32143
  • Product descriptionL(+)-Amethopterin hydrate
  • Packaging10g
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA32143
  • Product descriptionL(+)-Amethopterin hydrate
  • Packaging25g
  • Price$250
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Activate Scientific AS110159-B Methotrexate hydrate 99% 1g $30 2021-12-16 Buy
AHH MT-16699 Methotrexate hydrate 98% 0.5g $398 2021-12-16 Buy
AK Scientific I965 L-Amethopterinhydrate 5g $1023 2021-12-16 Buy
AK Scientific 2504AH Methotrexate hydrate 5g $706 2021-12-16 Buy
AK Scientific J11212 Methotrexatedihydrate 5mg $29 2021-12-16 Buy
Ambeed A575327 Methotrexatexhydrate 98% 250mg $10 2021-12-16 Buy
Ambeed A575327 Methotrexatexhydrate 98% 1g $19 2021-12-16 Buy
Ambeed A575327 Methotrexatexhydrate 98% 5g $63 2021-12-16 Buy
Ambeed A575327 Methotrexatexhydrate 98% 25g $218 2021-12-16 Buy
American Custom Chemicals Corporation API0007745 METHOTREXATE HYDRATE 95.00% 100MG $622.13 2021-12-16 Buy
American Custom Chemicals Corporation API0007745 METHOTREXATE HYDRATE 95.00% 1G $708.31 2021-12-16 Buy
American Custom Chemicals Corporation API0007745 METHOTREXATE HYDRATE 95.00% 5G $1144.84 2021-12-16 Buy
Biosynth Carbosynth FA32143 L(+)-Amethopterin hydrate 2g $60 2021-12-16 Buy
Biosynth Carbosynth FA32143 L(+)-Amethopterin hydrate 5G $100 2021-12-16 Buy
Biosynth Carbosynth FA32143 L(+)-Amethopterin hydrate 10g $150 2021-12-16 Buy
Biosynth Carbosynth FA32143 L(+)-Amethopterin hydrate 25g $250 2021-12-16 Buy

Properties

Melting point :195 °C
storage temp. :-20°C
solubility :H2O: insoluble
form :powder
color :yellow
optical activity :[α]/D +21.0±2.0°
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :FBOZXECLQNJBKD-ZDUSSCGKSA-N

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Methotrexate (MTX) is similar in structure to folic acid and aminopterin . It acts by inhibiting the metabolism of folic acid and blocking key enzymes in the synthesis of purines and pyrimidines required for cell proliferation. MTX is known to induce adenosine release, which mediates many of its anti-inflammatory effects, including the reduction of proinflammatory cytokines. Formulations containing MTX have been used as immunosuppressants, in the treatment of cancer, autoimmune disease, ectopic pregnancy, and for the induction of medical abortions. MTX formulations have been considered the gold standard of disease-modifying antirheumatic drug (DMARD) therapy to treat both the immune-inflammatory and joint destructive processes of rheumatoid arthritis.

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