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ChemicalBook >> CAS DataBase List >> L-Leucine

L-Leucine

L-Leucine price.
  • $10 - $2980
  • Product name: L-Leucine
  • CAS: 61-90-5
  • MF: C6H13NO2
  • MW: 131.17
  • EINECS:200-522-0
  • MDL Number:MFCD00002617
  • Synonyms:(s)-2-amino-4-methylvalericacid ;1-Leucine;2-amino-4-methylpentanoicacid ;2-amino-4-methyl-valericaci ;4-methyl-l-norvalin ;alpha-Amino-gamma-methylvaleric acid;alpha-amino-gamma-methylvalericacid ;iso-C4H9CH(NH2)COOH
73 prices
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  • ManufacturerAcrotein
  • Product numberNA-0188
  • Product descriptionL-Leucine 97%
  • Packaging1kg
  • Price$88
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-16362
  • Product descriptionL-Leucine 98%
  • Packaging25g
  • Price$708
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ53020
  • Product descriptionL-Leucine
  • Packaging25g
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA12311
  • Product descriptionL-Leucine, 99%
  • Packaging100g
  • Price$59.7
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ18280
  • Product descriptionL-Leucine, 98.5-101.5% (dry basis), Ultrapure, Affymetrix/USB
  • Packaging100g
  • Price$66.6
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ62824
  • Product descriptionL-Leucine, Cell Culture Reagent
  • Packaging100g
  • Price$108
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberA12311
  • Product descriptionL-Leucine, 99%
  • Packaging500g
  • Price$194
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ62824
  • Product descriptionL-Leucine, Cell Culture Reagent
  • Packaging250g
  • Price$211.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ18280
  • Product descriptionL-Leucine, 98.5-101.5% (dry basis), Ultrapure, Affymetrix/USB
  • Packaging1kg
  • Price$266
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ62824
  • Product descriptionL-Leucine, Cell Culture Reagent
  • Packaging500g
  • Price$401.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA12311
  • Product descriptionL-Leucine, 99%
  • Packaging2500g
  • Price$832
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ18280
  • Product descriptionL-Leucine, 98.5-101.5% (dry basis), Ultrapure, Affymetrix/USB
  • Packaging5kg
  • Price$999
  • Updated2023-06-20
  • Buy
  • ManufacturerArctom
  • Product numberCFN94811
  • Product descriptionL-Leucine
  • Packaging20mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number29817
  • Product descriptionL-Leucine ≥ 99% (Assay by titration)
  • Packaging25G
  • Price$10
  • Updated2021-12-16
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  • ManufacturerChem-Impex
  • Product number00200
  • Product descriptionL-Leucine 98.5 - 101.5% (Assay by titration)
  • Packaging100G
  • Price$12.5
  • Updated2021-12-16
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  • ManufacturerChem-Impex
  • Product number33065
  • Product descriptionL-Leucine, from non animal origin,suitable for cell culture 99 - 101% (Assay by titration,on dry basis)
  • Packaging25G
  • Price$15
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Acrotein NA-0188 L-Leucine 97% 1kg $88 2021-12-16 Buy
AHH MT-16362 L-Leucine 98% 25g $708 2021-12-16 Buy
AK Scientific J53020 L-Leucine 25g $10 2021-12-16 Buy
Alfa Aesar A12311 L-Leucine, 99% 100g $59.7 2023-06-20 Buy
Alfa Aesar J18280 L-Leucine, 98.5-101.5% (dry basis), Ultrapure, Affymetrix/USB 100g $66.6 2023-06-20 Buy
Alfa Aesar J62824 L-Leucine, Cell Culture Reagent 100g $108 2024-03-01 Buy
Alfa Aesar A12311 L-Leucine, 99% 500g $194 2023-06-20 Buy
Alfa Aesar J62824 L-Leucine, Cell Culture Reagent 250g $211.65 2024-03-01 Buy
Alfa Aesar J18280 L-Leucine, 98.5-101.5% (dry basis), Ultrapure, Affymetrix/USB 1kg $266 2023-06-20 Buy
Alfa Aesar J62824 L-Leucine, Cell Culture Reagent 500g $401.65 2024-03-01 Buy
Alfa Aesar A12311 L-Leucine, 99% 2500g $832 2023-06-20 Buy
Alfa Aesar J18280 L-Leucine, 98.5-101.5% (dry basis), Ultrapure, Affymetrix/USB 5kg $999 2023-06-20 Buy
Arctom CFN94811 L-Leucine 20mg $30 2021-12-16 Buy
Chem-Impex 29817 L-Leucine ≥ 99% (Assay by titration) 25G $10 2021-12-16 Buy
Chem-Impex 00200 L-Leucine 98.5 - 101.5% (Assay by titration) 100G $12.5 2021-12-16 Buy
Chem-Impex 33065 L-Leucine, from non animal origin,suitable for cell culture 99 - 101% (Assay by titration,on dry basis) 25G $15 2021-12-16 Buy

Properties

Melting point :>300 °C (lit.)
alpha :15.4 º (c=4, 6N HCl)
Boiling point :122-134 °C(Press: 2-3 Torr)
Density :1,293 g/cm3
vapor pressure :<1 hPa (20 °C)
refractive index :1.4630 (estimate)
FEMA :3297 | L-LEUCINE
Flash point :145-148°C
storage temp. :2-8°C
solubility :1 M HCl: 50 mg/mL
form :powder
pka :2.328(at 25℃)
color :White to Off-white
PH :5.5-6.5 (20g/l, H2O, 20℃)
Odor :at 100.00?%. odorless
optical activity :[α]20/D +15.5°, c = 2 in 6 M HCl
Water Solubility :22.4 g/L (20 C)
λmax :λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.05 JECFA Number :1423
Merck :14,5451
Sublimation :145-148 ºC
BRN :1721722
Stability :Stability Moisture and light sensitive. Incompatible with strong oxidising agents.
LogP :0.80
CAS DataBase Reference :61-90-5(CAS DataBase Reference)
NIST Chemistry Reference :Leucine(61-90-5)
EPA Substance Registry System :L-Leucine (61-90-5)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

L-leucine is one of the eight essential amino acids, and belonging to the aliphatic amino acids within twenty kinds of proteins. L-leucine and L-isoleucine and L-valine are called three branched chain amino acids. L-leucineLeucine and D-leucine are enantiomers . It is a white shiny hexahedral crystal or white crystalline powder at room temperature , Odorless, slightly bitter . In the presence of hydrocarbons ,it is stable in the aqueous mineral acid. Per gram is dissolved in 40ml water and about 100ml acetic acid. Very slightly soluble in ethanol or ether, dissolved in formic acid, dilute hydrochloric acid, a solution of alkali hydroxides and a solution of carbonates.
L-leucine can promote insulin secretion, can lower blood sugar; promote sleep, reduce sensitivity to pain, migraine headaches, anxiety and ease tension, reduce symptoms of chemical reactions disorder in the body caused by alcohol , and helps control alcoholism; it has a role in the treatment of dizziness , also can promote skin wound and bone healing, so doctors usually advise patients to take leucine supplements after surgery. amino acid infusion and comprehensive amino acid preparations are often formulated to be used in the treatment or health care; also be used as food, cosmetics and feed additives and plant growth promoter.
The best food sources of leucine include brown rice, beans, meat, nuts, soy flour, and whole wheat. Excessive intake can also cause side effects, high intake can cause pellagra, vitamin A deficiency, dermatitis, diarrhea, mental disorders and other issues,which needs to be paid attention to . Diet containing too much leucine will increase the number of ammonia in the body and destroy the liver and kidney function. Therefore, patients with impaired liver or kidney function should not be excessive intake, otherwise it will exacerbate the condition.

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