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ChemicalBook >> CAS DataBase List >> JC-1

JC-1

JC-1 price.
  • $68 - $3900
  • Product name: JC-1
  • CAS: 3520-43-2
  • MF: C25H27Cl4N4.I
  • MW: 652.228
  • EINECS:200-258-5
  • MDL Number:MFCD00188475
  • Synonyms:5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine iodide;JC-1;JC-1,5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethyl-imidacarbocyanine iodide, 5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethylbenzimidazolocarbocyanine iodide, CBIC2(3);JC-1 jodide;1h-benzimidazolium, 5,6-dichloro-2[3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2h-benzimidazol-2-ylidene)-1-propenyl]-1,3-diethyl-, Iodide;5,6-dichloro-2-[3-(5,6-dichloro-1,3-diethyl-2-benzimidazolinylidene)propenyl]-1,3-diethylbenzimidazolium Iodide;Benzimidazolium, 5,6-dichloro-2-[3-(5,6-dichloro-1,3diethyl-2-benzimidazolinylidene)propenyl]-1,3-diethyl-, Iodide;Benzimidazolocarbocyanine Iodide, 5,50,6,60-tetrachloro-1,10,3,30-tetraethyl-
20 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 002
  • 001
  • 003
  • 1mg
  • 2mg
  • 2.5mg
  • 5mg
  • 10mg
  • 50mg
  • 200mg
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3568-M005
  • Product descriptionJC-1 ≥98%(NMR)
  • Packaging5mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3006BB
  • Product description1,1',3,3'-Tetraethyl-5,5',6,6'-tetrachloroimidacarbocyanineiodide
  • Packaging1mg
  • Price$174
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3516
  • Product descriptionJC-1
  • Packaging1mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3516
  • Product descriptionJC-1
  • Packaging200mg
  • Price$2299
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15003
  • Product descriptionJC-1 ≥90%
  • Packaging1mg
  • Price$68
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15003
  • Product descriptionJC-1 ≥90%
  • Packaging5mg
  • Price$302
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15003
  • Product descriptionJC-1 ≥90%
  • Packaging10mg
  • Price$535
  • Updated2024-03-01
  • Buy
  • ManufacturerChem-Impex
  • Product number41986
  • Product descriptionJC-1,≥97%(HPLC),suitableforHematology&Histology ≥97%(HPLC)
  • Packaging5MG
  • Price$542.8
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1148
  • Product descriptionJC-1 99.00%
  • Packaging2mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1148
  • Product descriptionJC-1 99.00%
  • Packaging5mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1148
  • Product descriptionJC-1 99.00%
  • Packaging10mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1148
  • Product descriptionJC-1 99.00%
  • Packaging50mg
  • Price$1280
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11137791
  • Product descriptionJC-1 97%
  • Packaging5mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11137791
  • Product descriptionJC-1 97%
  • Packaging10mg
  • Price$265
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product number025867
  • Product descriptionJC-1
  • Packaging001
  • Price$950
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product number025867
  • Product descriptionJC-1
  • Packaging002
  • Price$1900
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3568-M005 JC-1 ≥98%(NMR) 5mg $180 2021-12-16 Buy
AK Scientific 3006BB 1,1',3,3'-Tetraethyl-5,5',6,6'-tetrachloroimidacarbocyanineiodide 1mg $174 2021-12-16 Buy
ApexBio Technology A3516 JC-1 1mg $70 2021-12-16 Buy
ApexBio Technology A3516 JC-1 200mg $2299 2021-12-16 Buy
Cayman Chemical 15003 JC-1 ≥90% 1mg $68 2024-03-01 Buy
Cayman Chemical 15003 JC-1 ≥90% 5mg $302 2024-03-01 Buy
Cayman Chemical 15003 JC-1 ≥90% 10mg $535 2024-03-01 Buy
Chem-Impex 41986 JC-1,≥97%(HPLC),suitableforHematology&Histology ≥97%(HPLC) 5MG $542.8 2021-12-16 Buy
ChemScene CS-1148 JC-1 99.00% 2mg $96 2021-12-16 Buy
ChemScene CS-1148 JC-1 99.00% 5mg $180 2021-12-16 Buy
ChemScene CS-1148 JC-1 99.00% 10mg $300 2021-12-16 Buy
ChemScene CS-1148 JC-1 99.00% 50mg $1280 2021-12-16 Buy
Crysdot CD11137791 JC-1 97% 5mg $160 2021-12-16 Buy
Crysdot CD11137791 JC-1 97% 10mg $265 2021-12-16 Buy
DC Chemicals 025867 JC-1 001 $950 2021-12-16 Buy
DC Chemicals 025867 JC-1 002 $1900 2021-12-16 Buy

Properties

Melting point :275–278 ℃
storage temp. :room temp
solubility :Soluble in methanol, N,N-dimethyl formamide, dimethyl sulfoxide
form :crystals
color :Deep red
λmax :514nm
Stability :Store as supplied desiccated at -20°C for up to 2 years from the date of purchase. Solutions in DMSO or distilled water may be stored at 4°C for up to 1 year. DO NOT FREEZE/THAW SOLUTIONS. Sterilize solutions only by filtration, not by autoclaving
Biological Applications :Detectingmitochondrialmembrane potential,ABCB1,ABCC1,and ABCG2 transporters inhibitors,nucleic acid hybridization,prostate cancer; treating cellular death,Alzheimer’s disease; apoptosis assay; cytotoxicity assay; hematotoxicity
Major Application :Langmuir-Blodgett films; lasing systems; nonlinear optical materials; photographic materials1,
InChIKey :FYNNIUVBDKICAX-UHFFFAOYSA-M

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P391 Collect spillage. Hazardous to the aquatic environment
P501 Dispose of contents/container to..…

Description

JC-1 is a membrane-permeable cationic dye that is used to study mitochondrial integrity in the context of cellular apoptosis. It selectively enters mitochondria and changes fluorescence characteristics with alteration in mitochondrial transmembrane potential (ΔΨm). In healthy cells with a high mitochondrial ΔΨm, JC-1 forms complexes known as J-aggregates, which fluoresce red/orange and may be detected using FL2 settings by flow cytometry. A drop in ΔΨm, a very early event in apoptosis, results in JC-1 monomers, which fluoresce green (FL1 settings on flow cytometers). JC-1 may also be used with fluorescent microscopes or plate readers, using excitation at 520-570 nm and emission at 570-610 nm for J-aggregates and excitation at 485 nm and emission at 535 nm for monomers.

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