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ChemicalBook >> CAS DataBase List >> Glibenclamide

Glibenclamide

Glibenclamide price.
  • $6 - $625
  • Product name: Glibenclamide
  • CAS: 10238-21-8
  • MF: C23H28ClN3O5S
  • MW: 494
  • EINECS:233-570-6
  • MDL Number:MFCD00056625
  • Synonyms:LABOTEST-BB LT00244861;GLIBENCLAMIDE;GLYBURIDE USP;GlibenclamideGlibenclamideBp;5-CHLORO-N-[4-(CYCLOHEXYLUREIDOSULFONYL)PHENETHYL]-2-METHOXYBENZAMIDE;5-CHLORO-N-[2-[4-[[[(CYCLOHEXYLAMINO)CARBONYL]AMINO]-SULFONYL]PHENYL]ETHYL]-2-METHOXYBENZAMIDE;adiab ;azuglucon
38 prices
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Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Atlantic Research Chemicals
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Chem-Impex
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
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  • 1gm:
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3613-G001
  • Product descriptionGlyburide(USP) ≥98%
  • Packaging1g
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3613-G010
  • Product descriptionGlyburide(USP) ≥98%
  • Packaging10g
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberG621
  • Product descriptionGlibenclamide
  • Packaging500g
  • Price$354
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberB21459
  • Product descriptionGlybenzcyclamide, 99%
  • Packaging100g
  • Price$339
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberB21459
  • Product descriptionGlybenzcyclamide, 99%
  • Packaging25g
  • Price$99.2
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA212350
  • Product description5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide 98%
  • Packaging1g
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA212350
  • Product description5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide 98%
  • Packaging25g
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA212350
  • Product description5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide 98%
  • Packaging100g
  • Price$94
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1296
  • Product descriptionGlibenclamide
  • Packaging1g
  • Price$37
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1296
  • Product descriptionGlibenclamide
  • Packaging5g
  • Price$43
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1296
  • Product descriptionGlibenclamide
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN80103
  • Product descriptionGlibenclamide
  • Packaging20mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAtlantic Research Chemicals
  • Product numberAN049192
  • Product description5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide 95%
  • Packaging1gm:
  • Price$21.21
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb104866
  • Product descriptionGlibenclamide >98%,Standard References Grade
  • Packaging20mg
  • Price$569.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBG166164
  • Product descriptionGlibenclamide
  • Packaging100mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number37910
  • Product descriptionGlibenclamide,98.5%(Assaybytitration,HPLC) 98.5%(Assaybytitration,HPLC)
  • Packaging5G
  • Price$28
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3613-G001 Glyburide(USP) ≥98% 1g $28 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-3613-G010 Glyburide(USP) ≥98% 10g $80 2021-12-16 Buy
AK Scientific G621 Glibenclamide 500g $354 2021-12-16 Buy
Alfa Aesar B21459 Glybenzcyclamide, 99% 100g $339 2024-03-01 Buy
Alfa Aesar B21459 Glybenzcyclamide, 99% 25g $99.2 2024-03-01 Buy
Ambeed A212350 5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide 98% 1g $6 2021-12-16 Buy
Ambeed A212350 5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide 98% 25g $39 2021-12-16 Buy
Ambeed A212350 5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide 98% 100g $94 2021-12-16 Buy
ApexBio Technology B1296 Glibenclamide 1g $37 2021-12-16 Buy
ApexBio Technology B1296 Glibenclamide 5g $43 2021-12-16 Buy
ApexBio Technology B1296 Glibenclamide 10mM(in 1mL DMSO) $50 2021-12-16 Buy
Arctom CFN80103 Glibenclamide 20mg $30 2021-12-16 Buy
Atlantic Research Chemicals AN049192 5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide 95% 1gm: $21.21 2021-12-16 Buy
Biorbyt Ltd orb104866 Glibenclamide >98%,Standard References Grade 20mg $569.5 2021-12-16 Buy
Biosynth Carbosynth BG166164 Glibenclamide 100mg $50 2021-12-16 Buy
Chem-Impex 37910 Glibenclamide,98.5%(Assaybytitration,HPLC) 98.5%(Assaybytitration,HPLC) 5G $28 2021-12-16 Buy

Properties

Melting point :173-175°C
Density :1.1805 (rough estimate)
refractive index :1.6100 (estimate)
storage temp. :2-8°C
solubility :ethanol: soluble2mg/mL
form :White solid
pka :5.3(at 25℃)
color :White
Water Solubility :Soluble in ethanol (5 mg/mL), DMSO (25 mg/mL), chloroform (1:36), methanol (1:250), and DMF. Insoluble in water.
Merck :14,4478
BCS Class :2
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :ZNNLBTZKUZBEKO-UHFFFAOYSA-N
CAS DataBase Reference :10238-21-8(CAS DataBase Reference)
NIST Chemistry Reference :Glyburide(10238-21-8)
EPA Substance Registry System :Benzamide, 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy- (10238-21-8)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P307+P311, P321,P405, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Glyburide (Glibenclamide) is a sulfonylurea compound that modulates insulin production. Sulfonylureas bind to ATP-dependent K+ channels in beta cells of the pancreas, depolarizing them and stimulating the release of Ca2+, which in turn stimulates insulin production. Glyburide (Glibenclamide) is an ATP-dependent K+ channel (KIR6, KATP) and CFTR Cl- channel blocker. This compound inhibits recombinant CFTR Cl- channels (IC50 = 20 ?M).

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