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ChemicalBook >> CAS DataBase List >> Doxazosin mesylate

Doxazosin mesylate

Doxazosin mesylate  price.
  • $39 - $1800
  • Product name: Doxazosin mesylate
  • CAS: 77883-43-3
  • MF: C24H29N5O8S
  • MW: 547.58
  • EINECS:1308068-626-2
  • MDL Number:MFCD00216023
  • Synonyms:ALFADIL;CARDENALIN;DOXAZOSIN MESYLATE;DOXAZOSIN METHANESULFONATE;UK-33274-27;doxazosinmesylate(patented-nosupply) ;piperazine,1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((2,3-dihydro-1,4-benzod ;DOXAZOSIN MEYLATE
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  • AHH
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  • y0000553
  • 10mM(in 1mL DMSO)
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  • 25g
  • ManufacturerAHH
  • Product numberAPI-1545
  • Product descriptionDoxazosin Mesylate 98%
  • Packaging10g
  • Price$680
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ10294
  • Product descriptionDoxazosin Mesylate
  • Packaging100mg
  • Price$94
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberA730
  • Product descriptionDoxazosin Mesylate
  • Packaging10g
  • Price$534
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0024697
  • Product descriptionDOXAZOSIN MESYLATE 95.00%
  • Packaging1G
  • Price$129.15
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0024697
  • Product descriptionDOXAZOSIN MESYLATE 95.00%
  • Packaging2.5G
  • Price$1147.43
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA2884
  • Product descriptionDoxazosin Mesylate
  • Packaging100mg
  • Price$70
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA2884
  • Product descriptionDoxazosin Mesylate
  • Packaging10mM(in 1mL DMSO)
  • Price$70
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number1631
  • Product descriptionDoxazosin Mesylate
  • Packaging100mg
  • Price$39
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number1631
  • Product descriptionDoxazosin Mesylate
  • Packaging1g
  • Price$115
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number1631
  • Product descriptionDoxazosin Mesylate
  • Packaging5g
  • Price$390
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberBD164387
  • Product descriptionDoxazosin mesylate
  • Packaging100mg
  • Price$50
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFD22603
  • Product descriptionDoxazosin mesylate
  • Packaging1g
  • Price$65
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFD22603
  • Product descriptionDoxazosin mesylate
  • Packaging2g
  • Price$120
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFD22603
  • Product descriptionDoxazosin mesylate
  • Packaging5G
  • Price$250
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFD22603
  • Product descriptionDoxazosin mesylate
  • Packaging10g
  • Price$400
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFD22603
  • Product descriptionDoxazosin mesylate
  • Packaging25g
  • Price$600
  • Updated2021-12-16
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Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1545 Doxazosin Mesylate 98% 10g $680 2021-12-16 Buy
AK Scientific J10294 Doxazosin Mesylate 100mg $94 2021-12-16 Buy
AK Scientific A730 Doxazosin Mesylate 10g $534 2021-12-16 Buy
American Custom Chemicals Corporation API0024697 DOXAZOSIN MESYLATE 95.00% 1G $129.15 2021-12-16 Buy
American Custom Chemicals Corporation API0024697 DOXAZOSIN MESYLATE 95.00% 2.5G $1147.43 2021-12-16 Buy
ApexBio Technology A2884 Doxazosin Mesylate 100mg $70 2021-12-16 Buy
ApexBio Technology A2884 Doxazosin Mesylate 10mM(in 1mL DMSO) $70 2021-12-16 Buy
AvaChem 1631 Doxazosin Mesylate 100mg $39 2021-12-16 Buy
AvaChem 1631 Doxazosin Mesylate 1g $115 2021-12-16 Buy
AvaChem 1631 Doxazosin Mesylate 5g $390 2021-12-16 Buy
Biosynth Carbosynth BD164387 Doxazosin mesylate 100mg $50 2021-12-16 Buy
Biosynth Carbosynth FD22603 Doxazosin mesylate 1g $65 2021-12-16 Buy
Biosynth Carbosynth FD22603 Doxazosin mesylate 2g $120 2021-12-16 Buy
Biosynth Carbosynth FD22603 Doxazosin mesylate 5G $250 2021-12-16 Buy
Biosynth Carbosynth FD22603 Doxazosin mesylate 10g $400 2021-12-16 Buy
Biosynth Carbosynth FD22603 Doxazosin mesylate 25g $600 2021-12-16 Buy

Properties

Melting point :275-277°C
storage temp. :2-8°C
solubility :Slightly soluble in water, soluble in a mixture of 15 volumes of water and 35 volumes of tetrahydrofuran, slightly soluble in methanol, practically insoluble in acetone. It shows polymorphism (5.9), some forms may be hygroscopic
form :powder
color :white
BCS Class :1
Stability :Protect from light
InChIKey :VJECBOKJABCYMF-UHFFFAOYSA-N
CAS DataBase Reference :77883-43-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P314 Get medical advice/attention if you feel unwell.
P501 Dispose of contents/container to..…

Description

Doxazosin mesylate is a quinazoline compound that is a selective inhibitor of the alpha1 subtype of alpha adrenergic receptors. The chemical name of doxazosin mesylate is 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl) piperazine methanesulfonate.The empirical formula for doxazosin mesylate is C23H25N505 • CH4O3S and the molecular weight is 547.6.
Doxazosin mesylate is freely soluble in dimethylsulfoxide, soluble in dimethylformamide, slightly soluble in methanol, ethanol, and water (0.8% at 25°C), and very slightly soluble in acetone and methylene chloride. Each doxazosin mesylate tablet, for oral administration, contains 1 mg, 2 mg, 4 mg and 8 mg of doxazosin as the free base.
Doxazosin mesylate is a new generation of quinazolone α1 receptor blocker developed by the Pfizer company (United States), It has a long half-life, exerting its effects of dilating the blood vessels, reducing the vascular resistance and lowering the blood pressure through blocking the a 1 receptor. It selectively blocks the a1 adrenergic receptor of the prostate smooth muscle matrix, capsule and bladder neck, alleviating the symptoms of patients of benign prostatic hyperplasia, while having good curing effect on the dysuria caused by simple prostatic hyperplasia. In 1988, doxazosin, as a drug for the treatment of hypertension, had been listed in Denmark. In 1995, the US FDA had approved it for the treatment of benign prostatic hyperplasia. In 2002 September, Doxazosin controlled release tablets had been listed in China, providing a new option for the domestic treatment of benign prostatic hyperplasia. It has been recommended abroad as first-line clinical drugs of anti-hypertension and treatment of prostate disease.

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