DIHYDROMETHYSTICIN
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- $100 - $1279.46
- Product name: DIHYDROMETHYSTICIN
- CAS: 19902-91-1
- MF: C15H16O5
- MW: 276.28
- EINECS:
- MDL Number:MFCD00221731
- Synonyms:6-(2-(1,3-benzodioxol-5-yl)ethyl)-5,6-dihydro-4-methoxy-2h-pyran-2-on(s) ;6-dihydro-4-methoxy-6-(3,4-(methylenedioxy)phenethyl)-(s)-2h-pyran-2-on ;7,8-dihydromethysticin ;dhm ;DIHYDROMETHYLSTICIN;7,8-DIHYDROMETHYLSTICIN;5,6-Dihydro-4-methoxy-6-[2-(1,3-benzodioxol-5-yl)ethyl]-2H-pyran-2-one;6-[2-(1,3-Benzodioxol-5-yl)ethyl]-4-methoxy-5,6-dihydro-2H-pyran-2-one
15 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Arctom
- AvaChem
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 1mg
- 5mg
- 10MG
- 20mg
- ManufacturerAK Scientific
- Product numberX1123
- Product descriptionDihydromethysticin
- Packaging5mg
- Price$363
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHBL0000233
- Product description(+)-DIHYDROMETHYSTICIN 95.00%
- Packaging5MG
- Price$933.26
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHBL0000233
- Product description(+)-DIHYDROMETHYSTICIN 95.00%
- Packaging10MG
- Price$1279.46
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN90332
- Product descriptionDihydromethysticin ≥98%
- Packaging10mg
- Price$288
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1778
- Product descriptionDihydromethysticin
- Packaging5mg
- Price$119
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1778
- Product descriptionDihydromethysticin
- Packaging10mg
- Price$189
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number27644
- Product descriptionDihydromethysticin
- Packaging5mg
- Price$238
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-4245
- Product descriptionDihydromethysticin
- Packaging1mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4245
- Product descriptionDihydromethysticin
- Packaging5mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4245
- Product descriptionDihydromethysticin
- Packaging10mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002774
- Product descriptionDihydromethysticin 98+%
- Packaging5mg
- Price$126
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002774
- Product descriptionDihydromethysticin 98+%
- Packaging10mg
- Price$196
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDCE-020
- Product descriptiondihydromethysticin >98%,StandardReferencesGrade
- Packaging20mg
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product number52007
- Product description(+)-Dihydromethysticin analytical standard
- Packaging5mg
- Price$539
- Updated2022-05-15
- Buy
- ManufacturerTRC
- Product numberB203530
- Product description(6S)-6-[2-(1,3-Benzodioxol-5-yl)ethyl]-5,6-dihydro-4-methoxy-2H-pyran-2-one
- Packaging10mg
- Price$375
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | X1123 | Dihydromethysticin | 5mg | $363 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HBL0000233 | (+)-DIHYDROMETHYSTICIN 95.00% | 5MG | $933.26 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HBL0000233 | (+)-DIHYDROMETHYSTICIN 95.00% | 10MG | $1279.46 | 2021-12-16 | Buy |
| Arctom | CFN90332 | Dihydromethysticin ≥98% | 10mg | $288 | 2021-12-16 | Buy |
| AvaChem | 1778 | Dihydromethysticin | 5mg | $119 | 2021-12-16 | Buy |
| AvaChem | 1778 | Dihydromethysticin | 10mg | $189 | 2021-12-16 | Buy |
| Cayman Chemical | 27644 | Dihydromethysticin | 5mg | $238 | 2024-03-01 | Buy |
| ChemScene | CS-4245 | Dihydromethysticin | 1mg | $100 | 2021-12-16 | Buy |
| ChemScene | CS-4245 | Dihydromethysticin | 5mg | $250 | 2021-12-16 | Buy |
| ChemScene | CS-4245 | Dihydromethysticin | 10mg | $420 | 2021-12-16 | Buy |
| Crysdot | CD31002774 | Dihydromethysticin 98+% | 5mg | $126 | 2021-12-16 | Buy |
| Crysdot | CD31002774 | Dihydromethysticin 98+% | 10mg | $196 | 2021-12-16 | Buy |
| DC Chemicals | DCE-020 | dihydromethysticin >98%,StandardReferencesGrade | 20mg | $280 | 2021-12-16 | Buy |
| Sigma-Aldrich | 52007 | (+)-Dihydromethysticin analytical standard | 5mg | $539 | 2022-05-15 | Buy |
| TRC | B203530 | (6S)-6-[2-(1,3-Benzodioxol-5-yl)ethyl]-5,6-dihydro-4-methoxy-2H-pyran-2-one | 10mg | $375 | 2021-12-16 | Buy |
Properties
storage temp. :2-8°C
solubility :Chloroform (Slightly), Methanol (Slightly), Pyridine (Slightly)
Boiling point :476.1±45.0 °C(Predicted)
Density :1.28±0.1 g/cm3(Predicted)
Melting point :117-118 °C
form :Solid
color :White to Off-White
BRN :91699
Stability :Hygroscopic
InChIKey :RSIWXFIBHXYNFM-NSHDSACASA-N
LogP :1.810 (est)
solubility :Chloroform (Slightly), Methanol (Slightly), Pyridine (Slightly)
Boiling point :476.1±45.0 °C(Predicted)
Density :1.28±0.1 g/cm3(Predicted)
Melting point :117-118 °C
form :Solid
color :White to Off-White
BRN :91699
Stability :Hygroscopic
InChIKey :RSIWXFIBHXYNFM-NSHDSACASA-N
LogP :1.810 (est)
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Dihydromethysticin is a kavalactone originally isolated from P. methysticum (kava-kava) that has diverse biological activities, including efflux transporter inhibitory, antinociceptive, and neuroprotective properties. Dihydromethysticin is a P-glycoprotein (P-gp) inhibitor that increases uptake of the P-gp substrate calcein AM by 50% in P388 mouse leukemia cancer cells overexpressing P-gp when used at a concentration of 54.6 μM. Dihydromethysticin (275 mg/kg) has analgesic activity, increasing the latency to tail withdrawal in the tail-flick assay in mice. It also decreases the infarct size in a mouse model of ischemia induced by microbipolar coagulation of the left middle cerebral artery (MCA) when administered at a dose of 10 mg/kg.Related product price
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