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ChemicalBook >> CAS DataBase List >> DIAZOXIDE

DIAZOXIDE

DIAZOXIDE price.
  • $28 - $1290
  • Product name: DIAZOXIDE
  • CAS: 364-98-7
  • MF: C8H7ClN2O2S
  • MW: 230.67
  • EINECS:206-668-1
  • MDL Number:MFCD00078578
  • Synonyms:Eudemine ;DIAZOXIDE ACTIVATOR OF ATP-DEPE;DIAZOXIDE,USP;NSC-64198;Sch-6783;7-chloro-3-methyl-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide;Diazoxide,7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide;2h-1,2,4-benzothiadiazine,7-chloro-3-methyl-,1,1-dioxide
33 prices
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Brand
  • AHH
  • AK Scientific
  • Alfa Aesar
  • ApexBio Technology
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 200mg
  • d0950000
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  • 100
  • 10mg
  • 25mg
  • 100mg
  • 500mg
  • 1g
  • 5g
  • 250mg
  • 2g
  • 10mM(in 1mL DMSO)
  • ManufacturerAHH
  • Product numberMT-49942
  • Product descriptionDiazoxide 98%
  • Packaging5g
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5601
  • Product descriptionDiazoxide
  • Packaging10mg
  • Price$123
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ66010
  • Product descriptionDiazoxide, 98%
  • Packaging100mg
  • Price$56.6
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ66010
  • Product descriptionDiazoxide, 98%
  • Packaging500mg
  • Price$220
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ66010
  • Product descriptionDiazoxide, 98%
  • Packaging1g
  • Price$365
  • Updated2023-06-20
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6526
  • Product descriptionDiazoxide
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6526
  • Product descriptionDiazoxide
  • Packaging100mg
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS609575
  • Product description3-Methyl-7-chloro-1,2,4-benzothiadiazine1,1-dioxide 95%
  • Packaging250mg
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS609575
  • Product description3-Methyl-7-chloro-1,2,4-benzothiadiazine1,1-dioxide 95%
  • Packaging1g
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS609575
  • Product description3-Methyl-7-chloro-1,2,4-benzothiadiazine1,1-dioxide 95%
  • Packaging5g
  • Price$262
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFD21519
  • Product descriptionDiazoxide
  • Packaging1g
  • Price$62.5
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFD21519
  • Product descriptionDiazoxide
  • Packaging2g
  • Price$120
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFD21519
  • Product descriptionDiazoxide
  • Packaging5G
  • Price$175
  • Updated2021-12-16
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  • ManufacturerCayman Chemical
  • Product number14576
  • Product descriptionDiazoxide ≥99%
  • Packaging100mg
  • Price$63
  • Updated2024-03-01
  • Buy
  • ManufacturerChem-Impex
  • Product number37831
  • Product descriptionDiazoxide,≥98%(Assaybytitration,HPLC) ≥98%(Assaybytitration,HPLC)
  • Packaging250MG
  • Price$71.05
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number37831
  • Product descriptionDiazoxide,98%(Assaybytitration,HPLC) 98%(Assaybytitration,HPLC)
  • Packaging1G
  • Price$217.28
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-49942 Diazoxide 98% 5g $230 2021-12-16 Buy
AK Scientific SYN5601 Diazoxide 10mg $123 2021-12-16 Buy
Alfa Aesar J66010 Diazoxide, 98% 100mg $56.6 2023-06-20 Buy
Alfa Aesar J66010 Diazoxide, 98% 500mg $220 2023-06-20 Buy
Alfa Aesar J66010 Diazoxide, 98% 1g $365 2023-06-20 Buy
ApexBio Technology B6526 Diazoxide 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology B6526 Diazoxide 100mg $53 2021-12-16 Buy
Arctom AS609575 3-Methyl-7-chloro-1,2,4-benzothiadiazine1,1-dioxide 95% 250mg $28 2021-12-16 Buy
Arctom AS609575 3-Methyl-7-chloro-1,2,4-benzothiadiazine1,1-dioxide 95% 1g $75 2021-12-16 Buy
Arctom AS609575 3-Methyl-7-chloro-1,2,4-benzothiadiazine1,1-dioxide 95% 5g $262 2021-12-16 Buy
Biosynth Carbosynth FD21519 Diazoxide 1g $62.5 2021-12-16 Buy
Biosynth Carbosynth FD21519 Diazoxide 2g $120 2021-12-16 Buy
Biosynth Carbosynth FD21519 Diazoxide 5G $175 2021-12-16 Buy
Cayman Chemical 14576 Diazoxide ≥99% 100mg $63 2024-03-01 Buy
Chem-Impex 37831 Diazoxide,≥98%(Assaybytitration,HPLC) ≥98%(Assaybytitration,HPLC) 250MG $71.05 2021-12-16 Buy
Chem-Impex 37831 Diazoxide,98%(Assaybytitration,HPLC) 98%(Assaybytitration,HPLC) 1G $217.28 2021-12-16 Buy

Properties

Melting point :>310°C
Boiling point :414.8±47.0 °C(Predicted)
Density :1.3767 (rough estimate)
refractive index :1.6300 (estimate)
storage temp. :2-8°C
solubility :0.1 M NaOH: soluble
form :Solid
pka :pKa 8.5 (Uncertain)
color :White
Water Solubility :Soluble in 0.1M NaOH. Insoluble in water or in methanol.
λmax :268nm(MeOH)(lit.)
Merck :14,3004
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Diazoxide is a potassium channel activator that causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. The cellular release of potassium switches off voltage-gated calcium ion channels which inhibits the generation of an action potential. Diazoxide relaxes rat aorta rings with an ED50 value of 19.3 μM and has been used as a vasodilator in the treatment of hypertension. Diazoxide also decreases the secretion of insulin by activating pancreatic β cell potassium channels and, thus, it has been used to counter hypoglycemia in certain disease states.

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