DEPHOSTATIN
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- $292.95
- Product name: DEPHOSTATIN
- CAS: 151606-30-3
- MF: C7H8N2O3
- MW: 168.15
- EINECS:
- MDL Number:MFCD00467665
- Synonyms:DEPHOSTATIN;2-(N-METHYL-N-NITROSO)HYDROQUINONE;2-(METHYLNITROSOAMINO)-1,4-BENZENEDIOL;2,5-DIHYDROXY-N-METHYL-N-NITROSOANILINE;2-(methylnitrosoamino)-4-benzenediol ;1,4-Dihydroxy-N-methyl-N-nitrosoaniline, 2-(Methylnitrosoamino)-1,4-benzenediol, 2-(N-methyl-N-nitroso)hydroquinone;1,4-DIHYDROXY-N-METHYL-N-NITROSOANILINE;Dephostatin - CAS 151606-30-3 - Calbiochem
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Selected condition：
Brand
- American Custom Chemicals Corporation
Package
- 1MG
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008323
- Product descriptionDEPHOSTATIN 95.00%
- Packaging1MG
- Price$292.95
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0008323 | DEPHOSTATIN 95.00% | 1MG | $292.95 | 2021-12-16 | Buy |
Properties
Boiling point :424.1±45.0 °C(Predicted)
Density :1.36±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMSO: 22 mg/mL, soluble
pka :9.23±0.43(Predicted)
form :solid
color :light yellow
Density :1.36±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMSO: 22 mg/mL, soluble
pka :9.23±0.43(Predicted)
form :solid
color :light yellow
Safety Information
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Description
Dephostatin is a protein-tyrosine phosphatase (PTP1B and SH-PTP1) inhibitor known to control the intracellular signal transduction in various biological processes frequently negatively regulating protein-tyrosine phosphorylation. Dephostatin is a competitive protein-tyrosine phosphatase inhibitor isolated from a Streptomyces strain and has been used as a study tool for various processes and diseases. Shown to inhibit the growth of Jerkat cells and protein tyrosine phosphatase activity in membrane preparations from human neoplastic T cell lines.Due to its oxidizing effects, dephostatin was shown to release calcium from intracellular calcium pools and induce amylase secretion in rat pancreatic acinar cells. Additionally, it possesses the potential to be a nitric oxide (NO) donor for protein S-nitrosylation.
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