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ChemicalBook >> CAS DataBase List >> DEMECOLCINE

DEMECOLCINE

DEMECOLCINE price.
  • $30 - $1732.5
  • Product name: DEMECOLCINE
  • CAS: 477-30-5
  • MF: C21H25NO5
  • MW: 371.43
  • EINECS:207-514-6
  • MDL Number:MFCD00075459
  • Synonyms:substancef ;Colcemide;DEMECOLCINE HYBRI-MAXR;Colcemid-D3=Demecolcine-D3;N-Deacetyl-N-methyl(deutero)colchicine;COLCEMIDE(R);COLCEMID(R);DEMECOLCIN
27 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Alfa Aesar
  • Alichem
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • DC Chemicals
  • Labseeker
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 20mg
  • 50mg
  • 100MG
  • 5g
  • 20ml
  • 100ml
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3567-M001
  • Product descriptionColcemid ≥98%(HPLC)
  • Packaging1mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0182
  • Product descriptionDemecolcine
  • Packaging1mg
  • Price$139
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0182
  • Product descriptionDemecolcine
  • Packaging5mg
  • Price$198
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0182
  • Product descriptionDemecolcine
  • Packaging10mg
  • Price$276
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63900
  • Product descriptionColcemid 98+%
  • Packaging10mg
  • Price$222
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63900
  • Product descriptionColcemid
  • Packaging50mg
  • Price$914
  • Updated2023-06-20
  • Buy
  • ManufacturerAlichem
  • Product number477305
  • Product description(S)-1,2,3,10-Tetramethoxy-7-(methylamino)-6,7-dihydrobenzo[a]heptalen-9(5H)-one
  • Packaging10mg
  • Price$325.71
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number477305
  • Product description(S)-1,2,3,10-Tetramethoxy-7-(methylamino)-6,7-dihydrobenzo[a]heptalen-9(5H)-one
  • Packaging50mg
  • Price$1016.61
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002097
  • Product descriptionColcemid 95.00%
  • Packaging100MG
  • Price$1732.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002097
  • Product descriptionColcemid 95.00%
  • Packaging10MG
  • Price$721.88
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002097
  • Product descriptionColcemid 95.00%
  • Packaging1MG
  • Price$135.45
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15364
  • Product descriptionColcemid ≥98%
  • Packaging1mg
  • Price$30
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15364
  • Product descriptionColcemid ≥98%
  • Packaging5mg
  • Price$96
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15364
  • Product descriptionColcemid ≥98%
  • Packaging10mg
  • Price$178
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15364
  • Product descriptionColcemid ≥98%
  • Packaging50mg
  • Price$740
  • Updated2024-03-01
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDCZ-273
  • Product descriptionDemecolcine >98%
  • Packaging20mg
  • Price$280
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3567-M001 Colcemid ≥98%(HPLC) 1mg $30 2021-12-16 Buy
AK Scientific V0182 Demecolcine 1mg $139 2021-12-16 Buy
AK Scientific V0182 Demecolcine 5mg $198 2021-12-16 Buy
AK Scientific V0182 Demecolcine 10mg $276 2021-12-16 Buy
Alfa Aesar J63900 Colcemid 98+% 10mg $222 2023-06-20 Buy
Alfa Aesar J63900 Colcemid 50mg $914 2023-06-20 Buy
Alichem 477305 (S)-1,2,3,10-Tetramethoxy-7-(methylamino)-6,7-dihydrobenzo[a]heptalen-9(5H)-one 10mg $325.71 2021-12-16 Buy
Alichem 477305 (S)-1,2,3,10-Tetramethoxy-7-(methylamino)-6,7-dihydrobenzo[a]heptalen-9(5H)-one 50mg $1016.61 2021-12-16 Buy
American Custom Chemicals Corporation API0002097 Colcemid 95.00% 100MG $1732.5 2021-12-16 Buy
American Custom Chemicals Corporation API0002097 Colcemid 95.00% 10MG $721.88 2021-12-16 Buy
American Custom Chemicals Corporation API0002097 Colcemid 95.00% 1MG $135.45 2021-12-16 Buy
Cayman Chemical 15364 Colcemid ≥98% 1mg $30 2024-03-01 Buy
Cayman Chemical 15364 Colcemid ≥98% 5mg $96 2024-03-01 Buy
Cayman Chemical 15364 Colcemid ≥98% 10mg $178 2024-03-01 Buy
Cayman Chemical 15364 Colcemid ≥98% 50mg $740 2024-03-01 Buy
DC Chemicals DCZ-273 Demecolcine >98% 20mg $280 2021-12-16 Buy

Properties

Melting point :73-75°C
alpha :D20 -129.0° (c = 1 in chloroform)
Boiling point :501.11°C (rough estimate)
Density :1.2350 (rough estimate)
refractive index :1.5614 (estimate)
storage temp. :2-8°C
solubility :DMSO: 10 mg/mL
form :powder
pka :8.48±0.40(Predicted)
color :White to off-white
Sensitive :Air & Light Sensitive
BRN :2822892
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

Colcemid is a colchicine derivative that inhibits tubulin polymerization as potently as colchicine (IC50 = 2.1 and 2.4 μM, respectively) but is less toxic. At very low (nanomolar) concentrations, colcemid suppresses microtubule dynamicity and inhibits cell migration, while at micromolar levels it blocks microtubule assembly, arresting cells in metaphase. Mitotic block by colcemid is used to synchronize cells and for karyotyping in cytogenetic studies. Prolonged exposure to colcemid can activate p53, leading to apoptosis.

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