DEMECOLCINE
- $30 - $1732.5
- Product name: DEMECOLCINE
- CAS: 477-30-5
- MF: C21H25NO5
- MW: 371.43
- EINECS:207-514-6
- MDL Number:MFCD00075459
- Synonyms:substancef ;Colcemide;DEMECOLCINE HYBRI-MAXR;Colcemid-D3=Demecolcine-D3;N-Deacetyl-N-methyl(deutero)colchicine;COLCEMIDE(R);COLCEMID(R);DEMECOLCIN
27 prices
Selected condition:
Brand
- Adipogen Life Sciences
- AK Scientific
- Alfa Aesar
- Alichem
- American Custom Chemicals Corporation
- Cayman Chemical
- DC Chemicals
- Labseeker
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 20mg
- 50mg
- 100MG
- 5g
- 20ml
- 100ml
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3567-M001
- Product descriptionColcemid ≥98%(HPLC)
- Packaging1mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberV0182
- Product descriptionDemecolcine
- Packaging1mg
- Price$139
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberV0182
- Product descriptionDemecolcine
- Packaging5mg
- Price$198
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberV0182
- Product descriptionDemecolcine
- Packaging10mg
- Price$276
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ63900
- Product descriptionColcemid 98+%
- Packaging10mg
- Price$222
- Updated2023-06-20
- Buy
- ManufacturerAlfa Aesar
- Product numberJ63900
- Product descriptionColcemid
- Packaging50mg
- Price$914
- Updated2023-06-20
- Buy
- ManufacturerAlichem
- Product number477305
- Product description(S)-1,2,3,10-Tetramethoxy-7-(methylamino)-6,7-dihydrobenzo[a]heptalen-9(5H)-one
- Packaging10mg
- Price$325.71
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number477305
- Product description(S)-1,2,3,10-Tetramethoxy-7-(methylamino)-6,7-dihydrobenzo[a]heptalen-9(5H)-one
- Packaging50mg
- Price$1016.61
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002097
- Product descriptionColcemid 95.00%
- Packaging100MG
- Price$1732.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002097
- Product descriptionColcemid 95.00%
- Packaging10MG
- Price$721.88
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002097
- Product descriptionColcemid 95.00%
- Packaging1MG
- Price$135.45
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15364
- Product descriptionColcemid ≥98%
- Packaging1mg
- Price$30
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15364
- Product descriptionColcemid ≥98%
- Packaging5mg
- Price$96
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15364
- Product descriptionColcemid ≥98%
- Packaging10mg
- Price$178
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15364
- Product descriptionColcemid ≥98%
- Packaging50mg
- Price$740
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product numberDCZ-273
- Product descriptionDemecolcine >98%
- Packaging20mg
- Price$280
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Adipogen Life Sciences | AG-CR1-3567-M001 | Colcemid ≥98%(HPLC) | 1mg | $30 | 2021-12-16 | Buy |
AK Scientific | V0182 | Demecolcine | 1mg | $139 | 2021-12-16 | Buy |
AK Scientific | V0182 | Demecolcine | 5mg | $198 | 2021-12-16 | Buy |
AK Scientific | V0182 | Demecolcine | 10mg | $276 | 2021-12-16 | Buy |
Alfa Aesar | J63900 | Colcemid 98+% | 10mg | $222 | 2023-06-20 | Buy |
Alfa Aesar | J63900 | Colcemid | 50mg | $914 | 2023-06-20 | Buy |
Alichem | 477305 | (S)-1,2,3,10-Tetramethoxy-7-(methylamino)-6,7-dihydrobenzo[a]heptalen-9(5H)-one | 10mg | $325.71 | 2021-12-16 | Buy |
Alichem | 477305 | (S)-1,2,3,10-Tetramethoxy-7-(methylamino)-6,7-dihydrobenzo[a]heptalen-9(5H)-one | 50mg | $1016.61 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0002097 | Colcemid 95.00% | 100MG | $1732.5 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0002097 | Colcemid 95.00% | 10MG | $721.88 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0002097 | Colcemid 95.00% | 1MG | $135.45 | 2021-12-16 | Buy |
Cayman Chemical | 15364 | Colcemid ≥98% | 1mg | $30 | 2024-03-01 | Buy |
Cayman Chemical | 15364 | Colcemid ≥98% | 5mg | $96 | 2024-03-01 | Buy |
Cayman Chemical | 15364 | Colcemid ≥98% | 10mg | $178 | 2024-03-01 | Buy |
Cayman Chemical | 15364 | Colcemid ≥98% | 50mg | $740 | 2024-03-01 | Buy |
DC Chemicals | DCZ-273 | Demecolcine >98% | 20mg | $280 | 2021-12-16 | Buy |
Properties
Melting point :73-75°C
alpha :D20 -129.0° (c = 1 in chloroform)
Boiling point :501.11°C (rough estimate)
Density :1.2350 (rough estimate)
refractive index :1.5614 (estimate)
storage temp. :2-8°C
solubility :DMSO: 10 mg/mL
form :powder
pka :8.48±0.40(Predicted)
color :White to off-white
Sensitive :Air & Light Sensitive
BRN :2822892
Stability :Hygroscopic
alpha :D20 -129.0° (c = 1 in chloroform)
Boiling point :501.11°C (rough estimate)
Density :1.2350 (rough estimate)
refractive index :1.5614 (estimate)
storage temp. :2-8°C
solubility :DMSO: 10 mg/mL
form :powder
pka :8.48±0.40(Predicted)
color :White to off-white
Sensitive :Air & Light Sensitive
BRN :2822892
Stability :Hygroscopic
Safety Information
Symbol(GHS): | |||||||||||||||
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Signal word: | Danger | ||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
Colcemid is a colchicine derivative that inhibits tubulin polymerization as potently as colchicine (IC50 = 2.1 and 2.4 μM, respectively) but is less toxic. At very low (nanomolar) concentrations, colcemid suppresses microtubule dynamicity and inhibits cell migration, while at micromolar levels it blocks microtubule assembly, arresting cells in metaphase. Mitotic block by colcemid is used to synchronize cells and for karyotyping in cytogenetic studies. Prolonged exposure to colcemid can activate p53, leading to apoptosis.More related product prices
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