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ChemicalBook >> CAS DataBase List >> Cefapirin sodium

Cefapirin sodium

Cefapirin sodium price.
  • $8 - $1430
  • Product name: Cefapirin sodium
  • CAS: 24356-60-3
  • MF: C17H18N3NaO6S2
  • MW: 447.46
  • EINECS:246-194-2
  • MDL Number:MFCD07793329
  • Synonyms:cephapirin sodium crystalline;sodium (6R-trans)-3-(acetoxymethyl)-8-oxo-7-[(4-pyridylthio)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate ;CEPHAPIRIN BEUZATHINE;5-Thia-1-azabicyclo4.2.0oct-2-ene-2-carboxylic acid, 3-(acetyloxy)methyl-8-oxo-7-(4-pyridinylthio)acetylamino-, monosodium salt, (6R,7R)-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-(hydroxymethyl)-8-oxo-7-[2-(4-pyridylthio)acetamido]-, acetate (ester), monosodium salt (8CI);5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-8-oxo-7-[[(4-pyridinylthio)acetyl]amino]-, monosodium salt, (6R-trans)-;7-[α-(4-Pyridylthio)acetamido]cephalosporanic acid sodium salt;Ambrocef
26 prices
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  • AccelPharmtech
  • AHH
  • Ambeed
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • ChemScene
  • Crysdot
  • Sigma-Aldrich
  • TRC
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  • 10g
  • y0000240
  • 25G
  • 1KG
  • ManufacturerAccelPharmtech
  • Product numberAT2144
  • Product descriptionCefapirin sodium 95.00%
  • Packaging25G
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerAccelPharmtech
  • Product numberAT2144
  • Product descriptionCefapirin sodium 95.00%
  • Packaging1KG
  • Price$1430
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-49107
  • Product descriptionCephapirin 98%
  • Packaging25g
  • Price$490
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA139624
  • Product descriptionSodium(6R,7R)-3-(acetoxymethyl)-8-oxo-7-(2-(pyridin-4-ylthio)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 97%
  • Packaging10mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA139624
  • Product descriptionSodium(6R,7R)-3-(acetoxymethyl)-8-oxo-7-(2-(pyridin-4-ylthio)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 97%
  • Packaging25mg
  • Price$11
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA139624
  • Product descriptionSodium(6R,7R)-3-(acetoxymethyl)-8-oxo-7-(2-(pyridin-4-ylthio)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 97%
  • Packaging50mg
  • Price$14
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA139624
  • Product descriptionSodium(6R,7R)-3-(acetoxymethyl)-8-oxo-7-(2-(pyridin-4-ylthio)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 97%
  • Packaging100mg
  • Price$25
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA139624
  • Product descriptionSodium(6R,7R)-3-(acetoxymethyl)-8-oxo-7-(2-(pyridin-4-ylthio)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 97%
  • Packaging250mg
  • Price$50
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA139624
  • Product descriptionSodium(6R,7R)-3-(acetoxymethyl)-8-oxo-7-(2-(pyridin-4-ylthio)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 97%
  • Packaging1g
  • Price$121
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA139624
  • Product descriptionSodium(6R,7R)-3-(acetoxymethyl)-8-oxo-7-(2-(pyridin-4-ylthio)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 97%
  • Packaging5g
  • Price$347
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA139624
  • Product descriptionSodium(6R,7R)-3-(acetoxymethyl)-8-oxo-7-(2-(pyridin-4-ylthio)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 97%
  • Packaging10g
  • Price$590
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0000458
  • Product descriptionCEFAPIRIN SODIUM 95.00%
  • Packaging100MG
  • Price$413.7
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFC61434
  • Product descriptionCefapirin sodium
  • Packaging100mg
  • Price$100
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFC61434
  • Product descriptionCefapirin sodium
  • Packaging250mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC61434
  • Product descriptionCefapirin sodium
  • Packaging500mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC61434
  • Product descriptionCefapirin sodium
  • Packaging1g
  • Price$400
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AccelPharmtech AT2144 Cefapirin sodium 95.00% 25G $200 2021-12-16 Buy
AccelPharmtech AT2144 Cefapirin sodium 95.00% 1KG $1430 2021-12-16 Buy
AHH MT-49107 Cephapirin 98% 25g $490 2021-12-16 Buy
Ambeed A139624 Sodium(6R,7R)-3-(acetoxymethyl)-8-oxo-7-(2-(pyridin-4-ylthio)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 97% 10mg $8 2021-12-16 Buy
Ambeed A139624 Sodium(6R,7R)-3-(acetoxymethyl)-8-oxo-7-(2-(pyridin-4-ylthio)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 97% 25mg $11 2021-12-16 Buy
Ambeed A139624 Sodium(6R,7R)-3-(acetoxymethyl)-8-oxo-7-(2-(pyridin-4-ylthio)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 97% 50mg $14 2021-12-16 Buy
Ambeed A139624 Sodium(6R,7R)-3-(acetoxymethyl)-8-oxo-7-(2-(pyridin-4-ylthio)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 97% 100mg $25 2021-12-16 Buy
Ambeed A139624 Sodium(6R,7R)-3-(acetoxymethyl)-8-oxo-7-(2-(pyridin-4-ylthio)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 97% 250mg $50 2021-12-16 Buy
Ambeed A139624 Sodium(6R,7R)-3-(acetoxymethyl)-8-oxo-7-(2-(pyridin-4-ylthio)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 97% 1g $121 2021-12-16 Buy
Ambeed A139624 Sodium(6R,7R)-3-(acetoxymethyl)-8-oxo-7-(2-(pyridin-4-ylthio)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 97% 5g $347 2021-12-16 Buy
Ambeed A139624 Sodium(6R,7R)-3-(acetoxymethyl)-8-oxo-7-(2-(pyridin-4-ylthio)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 97% 10g $590 2021-12-16 Buy
American Custom Chemicals Corporation API0000458 CEFAPIRIN SODIUM 95.00% 100MG $413.7 2021-12-16 Buy
Biosynth Carbosynth FC61434 Cefapirin sodium 100mg $100 2021-12-16 Buy
Biosynth Carbosynth FC61434 Cefapirin sodium 250mg $200 2021-12-16 Buy
Biosynth Carbosynth FC61434 Cefapirin sodium 500mg $300 2021-12-16 Buy
Biosynth Carbosynth FC61434 Cefapirin sodium 1g $400 2021-12-16 Buy

Properties

Melting point :>177°C (dec.)
alpha :+152～+170゜(25℃/D)(c=2,H2O)(calculated on the dehydrous basis)
storage temp. :Inert atmosphere,2-8°C
solubility :Soluble in water, practically insoluble in methylene chloride.
form :powder
pka :pKa 2.15 (Uncertain)
color :Light Beige to Beige
InChIKey :VGEOUKPOQQEQSX-OALZAMAHSA-M
CAS DataBase Reference :24356-60-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P342+P311 IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

Description

Cephapirin sodium (Cefapirin sodium), a semisynthetic cephalosporin antibiotic, is bactericidal against strains of gram-positive and gram-negative bacteria.
Cephapirin is closely resembles cephalothin in chemical and pharmacokinetic properties. Cephapirin, have cephalosporanic acid core with the acetyloxymethyl group at the 3rd position and having IUPAC name (6R,7R)-3-(Acetoxymethy)-8- oxo-7-{[(pyridin-4-ylsulfanyl)acetyl]amino}-5-thia- 1-azabicyclo [4.2.0] oct-2-ene-2-carboxylic acid. It is unstable in acid and must be administered parenteral. It has similar mechanism as other cephalosporins. It is marketed under the trade name Cefadyl. It is effective against a wide variety of gram-positive and gramnegative bacteria; used as the sodium salt. Among the most serious adverse reactions of cefapirin, that is， neutropenia, leukopenia, anemia, bone marrowdepression, and allergic reactions, it has been discontinued in the United States (Wiesner, 1972).

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