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ChemicalBook >> CAS DataBase List >> AT-406(AT406)

AT-406(AT406)

AT-406(AT406) price.
  • $32 - $2025
  • Product name: AT-406(AT406)
  • CAS: 1071992-99-8
  • MF: C32H43N5O4
  • MW: 561.71
  • EINECS:
  • MDL Number:MFCD22124467
  • Synonyms:AT-406(AT406);(5S,8S,10aR)-N-benzhydryl-5-((S)-2-(MethylaMino)propanaMido)-3-(3-Methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxaMide;SM 406;(5S,8S,10aR)-N-(Diphenylmethyl)decahydro-5-[[(2S)-2-(methylamino)-1-oxopropyl]amino]-3-(3-methyl-1-oxobutyl)-6-oxopyrrolo[1,2-a][1,5]diazocine-8-carboxamide;AT406 (SM-406, ARRY-334543);(5S,8S,10aR)-N-(Diphenylmethyl)decahydro-5-[[(2S)-2-(methylamino)-1-oxopropyl]amino]-3-(3-methyl-1-oxobutyl)-6-oxopyrrolo[1,2-a][1,5]diazocine-8-carboxamide AT406 (SM-406, ARRY-334543);(5S,8S,10aR)-N-benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahyd;AT-406 (SM-406)
21 prices
Selected condition：
Brand
  • Ambeed
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
Package
  • 500μg
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAmbeed
  • Product numberA780789
  • Product description(5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide 98+%
  • Packaging2mg
  • Price$58
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA780789
  • Product description(5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide 98+%
  • Packaging5mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA780789
  • Product description(5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide 98+%
  • Packaging10mg
  • Price$148
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA780789
  • Product description(5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide 98+%
  • Packaging25mg
  • Price$331
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA780789
  • Product description(5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide 98+%
  • Packaging50mg
  • Price$506
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA780789
  • Product description(5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide 98+%
  • Packaging100mg
  • Price$1011
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3019
  • Product descriptionAT-406(SM-406)
  • Packaging5mg
  • Price$121
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3019
  • Product descriptionAT-406(SM-406)
  • Packaging25mg
  • Price$362
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19929
  • Product descriptionAT-406 ≥95%
  • Packaging500μg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19929
  • Product descriptionAT-406 ≥95%
  • Packaging1mg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19929
  • Product descriptionAT-406 ≥95%
  • Packaging5mg
  • Price$199
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19929
  • Product descriptionAT-406 ≥95%
  • Packaging10mg
  • Price$365
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM197334
  • Product descriptionAT406(SM-406,ARRY-334543) 98%
  • Packaging50mg
  • Price$380
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004655
  • Product descriptionAT406(SM-406,ARRY-334543) 98+%
  • Packaging5mg
  • Price$77
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004655
  • Product descriptionAT406(SM-406,ARRY-334543) 98+%
  • Packaging10mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004655
  • Product descriptionAT406(SM-406,ARRY-334543) 98+%
  • Packaging25mg
  • Price$266
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Ambeed A780789 (5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide 98+% 2mg $58 2021-12-16 Buy
Ambeed A780789 (5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide 98+% 5mg $96 2021-12-16 Buy
Ambeed A780789 (5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide 98+% 10mg $148 2021-12-16 Buy
Ambeed A780789 (5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide 98+% 25mg $331 2021-12-16 Buy
Ambeed A780789 (5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide 98+% 50mg $506 2021-12-16 Buy
Ambeed A780789 (5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide 98+% 100mg $1011 2021-12-16 Buy
ApexBio Technology A3019 AT-406(SM-406) 5mg $121 2021-12-16 Buy
ApexBio Technology A3019 AT-406(SM-406) 25mg $362 2021-12-16 Buy
Cayman Chemical 19929 AT-406 ≥95% 500μg $32 2024-03-01 Buy
Cayman Chemical 19929 AT-406 ≥95% 1mg $57 2024-03-01 Buy
Cayman Chemical 19929 AT-406 ≥95% 5mg $199 2024-03-01 Buy
Cayman Chemical 19929 AT-406 ≥95% 10mg $365 2024-03-01 Buy
Chemenu CM197334 AT406(SM-406,ARRY-334543) 98% 50mg $380 2021-12-16 Buy
Crysdot CD31004655 AT406(SM-406,ARRY-334543) 98+% 5mg $77 2021-12-16 Buy
Crysdot CD31004655 AT406(SM-406,ARRY-334543) 98+% 10mg $119 2021-12-16 Buy
Crysdot CD31004655 AT406(SM-406,ARRY-334543) 98+% 25mg $266 2021-12-16 Buy

Properties

Boiling point :840.6±65.0 °C(Predicted)
Density :1.21
storage temp. :Store at -20°C
solubility :≥27.65 mg/mL in DMSO; insoluble in H2O; ≥27 mg/mL in EtOH
form :solid
pka :13.65±0.40(Predicted)
color :White to off-white
InChIKey :LSXUTRRVVSPWDZ-MKKUMYSQSA-N
SMILES :N12[C@H](C(NC(C3=CC=CC=C3)C3=CC=CC=C3)=O)CC[C@]1([H])CCN(C(=O)CC(C)C)C[C@H](NC(=O)[C@@H](NC)C)C2=O

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

AT-406 is an orally bioavailable Smac/DIABLO mimetic and antagonist of the inhibitor of apoptosis proteins (IAPs). It binds to XIAP, cIAP1, and cIAP2 proteins with Ki values of 66.4, 1.9, and 5.1 nM, respectively. It has been shown to inhibit cancer cell growth in various human cancer cell lines and to induce apoptosis in xenograft tumors in mice.