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ChemicalBook >> CAS DataBase List >> FMOC-O-tert-Butyl-L-serine

FMOC-O-tert-Butyl-L-serine

FMOC-O-tert-Butyl-L-serine price.
  • $6 - $2360
  • Product name: FMOC-O-tert-Butyl-L-serine
  • CAS: 71989-33-8
  • MF: C22H25NO5
  • MW: 383.44
  • EINECS:276-260-6
  • MDL Number:MFCD00037127
  • Synonyms:O-tert-Butyl-N-Fmoc-L-serine;9-fluorenylmethoxycarbonyl-O-tert-butyl-L-serine;N-Fmoc-O-tert-Butyl-L-serine, Fmoc-O-tert-butyl-L-serine;N-FMOC-L-Ser (O-tert-Bu) OH;2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-[(2-methylpropan-2-yl)oxy]propanoic acid;N-(9H-Fluorene-9-ylmethoxycarbonyl)-O-tert-butyl-L-serine;N-(9H-Fluorene-9-ylmethoxycarbonyl)-O-tert-butylserine;N-Fmoc-O-tert-Butylserine
60 prices
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  • Acrotein
  • Activate Scientific
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  • ApexBio Technology
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Package
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  • ManufacturerAcrotein
  • Product numberNA-0556
  • Product descriptionN-Fmoc-O-tert-butyl-L-serine 97%
  • Packaging250g
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS91745
  • Product descriptionFmoc-O-(tert-butyl)-L-serine 95+% ee
  • Packaging5G
  • Price$20
  • Updated2021-12-16
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS91745
  • Product descriptionFmoc-O-(tert-butyl)-L-serine 95+% ee
  • Packaging25g
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS91745
  • Product descriptionFmoc-O-(tert-butyl)-L-serine 95+% ee
  • Packaging100g
  • Price$155
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberMT-13943
  • Product descriptionFmoc-Ser(t-Bu)-OH 98%
  • Packaging100g
  • Price$398
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ95887
  • Product descriptionFmoc-Ser(tBu)-OH
  • Packaging25g
  • Price$35
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberK220
  • Product descriptionFmoc-Ser(tBu)-OH
  • Packaging100g
  • Price$147
  • Updated2021-12-16
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  • ManufacturerAlfa Aesar
  • Product numberH59422
  • Product descriptionN-Fmoc-O-tert-butyl-L-serine, 98%
  • Packaging5g
  • Price$43.65
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberH59422
  • Product descriptionN-Fmoc-O-tert-butyl-L-serine, 98%
  • Packaging25g
  • Price$146.65
  • Updated2024-03-01
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAAA0001647
  • Product descriptionN-FMOC-SER(TERT-BU)-OH 95.00%
  • Packaging5G
  • Price$850.02
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAAA0001647
  • Product descriptionN-FMOC-SER(TERT-BU)-OH 95.00%
  • Packaging25G
  • Price$1290
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA7960
  • Product descriptionFmoc-Ser(tBu)-OH
  • Packaging25g
  • Price$38
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA7960
  • Product descriptionFmoc-Ser(tBu)-OH
  • Packaging100g
  • Price$115
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS011888
  • Product descriptionFmoc-Ser(tBu)-OH 98%
  • Packaging5g
  • Price$7
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS011888
  • Product descriptionFmoc-Ser(tBu)-OH 98%
  • Packaging10g
  • Price$9
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS011888
  • Product descriptionFmoc-Ser(tBu)-OH 98%
  • Packaging25g
  • Price$19
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Acrotein NA-0556 N-Fmoc-O-tert-butyl-L-serine 97% 250g $220 2021-12-16 Buy
Activate Scientific AS91745 Fmoc-O-(tert-butyl)-L-serine 95+% ee 5G $20 2021-12-16 Buy
Activate Scientific AS91745 Fmoc-O-(tert-butyl)-L-serine 95+% ee 25g $53 2021-12-16 Buy
Activate Scientific AS91745 Fmoc-O-(tert-butyl)-L-serine 95+% ee 100g $155 2021-12-16 Buy
AHH MT-13943 Fmoc-Ser(t-Bu)-OH 98% 100g $398 2021-12-16 Buy
AK Scientific J95887 Fmoc-Ser(tBu)-OH 25g $35 2021-12-16 Buy
AK Scientific K220 Fmoc-Ser(tBu)-OH 100g $147 2021-12-16 Buy
Alfa Aesar H59422 N-Fmoc-O-tert-butyl-L-serine, 98% 5g $43.65 2024-03-01 Buy
Alfa Aesar H59422 N-Fmoc-O-tert-butyl-L-serine, 98% 25g $146.65 2024-03-01 Buy
American Custom Chemicals Corporation AAA0001647 N-FMOC-SER(TERT-BU)-OH 95.00% 5G $850.02 2021-12-16 Buy
American Custom Chemicals Corporation AAA0001647 N-FMOC-SER(TERT-BU)-OH 95.00% 25G $1290 2021-12-16 Buy
ApexBio Technology A7960 Fmoc-Ser(tBu)-OH 25g $38 2021-12-16 Buy
ApexBio Technology A7960 Fmoc-Ser(tBu)-OH 100g $115 2021-12-16 Buy
Arctom AS011888 Fmoc-Ser(tBu)-OH 98% 5g $7 2021-12-16 Buy
Arctom AS011888 Fmoc-Ser(tBu)-OH 98% 10g $9 2021-12-16 Buy
Arctom AS011888 Fmoc-Ser(tBu)-OH 98% 25g $19 2021-12-16 Buy

Properties

Melting point :130.5-135.5 °C(lit.)
alpha :25 º (c=1,EtOAc 24 ºC)
Boiling point :510.36°C (rough estimate)
Density :1.2369 (rough estimate)
refractive index :24 ° (C=1, AcOEt)
storage temp. :2-8°C
solubility :Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form :powder to crystal
pka :3.44±0.10(Predicted)
color :White to Almost white
optical activity :[α]20/D +25.5±1°, c = 1% in ethyl acetate
BRN :3632013
InChI :InChI=1S/C22H25NO5/c1-22(2,3)28-13-19(20(24)25)23-21(26)27-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,23,26)(H,24,25)/t19-/m0/s1
InChIKey :REITVGIIZHFVGU-IBGZPJMESA-N
SMILES :C(O)(=O)[C@H](COC(C)(C)C)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS DataBase Reference :71989-33-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Fmoc-Ser(tBu)-OH is an N-terminal protected reagent used in the peptide synthesis. Some of the reported examples are:
  • Total synthesis of an antibiotic, daptomycin, by cyclization via a chemoselective serine ligation.
  • Preparation of MUC1, a T-cell helper peptide, using iterative pentafluorophenyl ester-mediated fragment condensations.
  • Linear solid-phase peptide synthesis of ubiquitin and diubiquitin.

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