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ChemicalBook >> CAS DataBase List >> 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid price.
  • $7 - $1628
  • Product name: 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid
  • CAS: 641569-94-0
  • MF: C17H14N4O2
  • MW: 306.32
  • EINECS:629-968-8
  • MDL Number:MFCD11521324
  • Synonyms:4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid;4-Methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzoic acid;Benzoic acid, 4-Methyl-3-[[4-(3-pyridinyl)-2-pyriMidinyl]aMino]-;4-Methyl-3-[[4-(3-pyridinyl)-2-pyriMidiny]aMino]benzoic acid;2-[(5-Carboxy-2-methylphenyl)amino]-4-(pyridin-3-yl)pyrimidine, 3-{2-[(5-Carboxy-2-methylphenyl)amino]pyrimidin-4-yl}pyridine;Nilotinib Intemediate 2;4-Methyl-3-((4-(pyridin-3-yl);Nilotinib EP Impurity D
25 prices
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  • AccelPharmtech
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Apolloscientific
  • AvaChem
  • Chemenu
  • Crysdot
  • Matrix Scientific
  • SynQuest Laboratories
  • TRC
Package
  • 25mg
  • 250mg
  • 1G
  • 5G
  • 10G
  • 25g
  • 100g
  • ManufacturerAccelPharmtech
  • Product numberAT8432
  • Product description4-methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)benzoicacid 99%
  • Packaging10G
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerAccelPharmtech
  • Product numberAT8432
  • Product description4-methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)benzoicacid 99%
  • Packaging5G
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerAccelPharmtech
  • Product numberAT8432
  • Product description4-methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)benzoicacid 99%
  • Packaging1G
  • Price$90
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ11466
  • Product descriptionNilotinibImpurity20
  • Packaging25mg
  • Price$39
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA114039
  • Product description4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoicacid 97%
  • Packaging250mg
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA114039
  • Product description4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoicacid 97%
  • Packaging1g
  • Price$17
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA114039
  • Product description4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoicacid 97%
  • Packaging5g
  • Price$51
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA114039
  • Product description4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoicacid 97%
  • Packaging10g
  • Price$92
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA114039
  • Product description4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoicacid 97%
  • Packaging25g
  • Price$176
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA114039
  • Product description4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoicacid 97%
  • Packaging100g
  • Price$491
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0075457
  • Product description4-METHYL-3-(4-(PYRIDIN-3-YL)PYRIMIDIN-2-YLAMINO)BENZOIC ACID 95.00%
  • Packaging250MG
  • Price$686.65
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0075457
  • Product description4-METHYL-3-(4-(PYRIDIN-3-YL)PYRIMIDIN-2-YLAMINO)BENZOIC ACID 95.00%
  • Packaging1G
  • Price$890.39
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberOR16087
  • Product description4-Methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzoicacid
  • Packaging250mg
  • Price$15
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberOR16087
  • Product description4-Methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzoicacid
  • Packaging1g
  • Price$19
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number10040
  • Product description4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid
  • Packaging1g
  • Price$195
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number10040
  • Product description4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid
  • Packaging5g
  • Price$395
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AccelPharmtech AT8432 4-methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)benzoicacid 99% 10G $110 2021-12-16 Buy
AccelPharmtech AT8432 4-methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)benzoicacid 99% 5G $100 2021-12-16 Buy
AccelPharmtech AT8432 4-methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)benzoicacid 99% 1G $90 2021-12-16 Buy
AK Scientific J11466 NilotinibImpurity20 25mg $39 2021-12-16 Buy
Ambeed A114039 4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoicacid 97% 250mg $7 2021-12-16 Buy
Ambeed A114039 4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoicacid 97% 1g $17 2021-12-16 Buy
Ambeed A114039 4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoicacid 97% 5g $51 2021-12-16 Buy
Ambeed A114039 4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoicacid 97% 10g $92 2021-12-16 Buy
Ambeed A114039 4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoicacid 97% 25g $176 2021-12-16 Buy
Ambeed A114039 4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoicacid 97% 100g $491 2021-12-16 Buy
American Custom Chemicals Corporation CHM0075457 4-METHYL-3-(4-(PYRIDIN-3-YL)PYRIMIDIN-2-YLAMINO)BENZOIC ACID 95.00% 250MG $686.65 2021-12-16 Buy
American Custom Chemicals Corporation CHM0075457 4-METHYL-3-(4-(PYRIDIN-3-YL)PYRIMIDIN-2-YLAMINO)BENZOIC ACID 95.00% 1G $890.39 2021-12-16 Buy
Apolloscientific OR16087 4-Methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzoicacid 250mg $15 2021-12-16 Buy
Apolloscientific OR16087 4-Methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzoicacid 1g $19 2021-12-16 Buy
AvaChem 10040 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid 1g $195 2021-12-16 Buy
AvaChem 10040 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid 5g $395 2021-12-16 Buy

Properties

Melting point :>257oC (dec.)
Boiling point :587.9±60.0 °C(Predicted)
Density :1.336
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
pka :4.35±0.10(Predicted)
form :Solid
color :Pale Beige
Stability :Hygroscopic
InChI :InChI=1S/C17H14N4O2/c1-11-4-5-12(16(22)23)9-15(11)21-17-19-8-6-14(20-17)13-3-2-7-18-10-13/h2-10H,1H3,(H,22,23)(H,19,20,21)
InChIKey :LDLZPHLSVKGFSC-UHFFFAOYSA-N
SMILES :C(O)(=O)C1=CC=C(C)C(NC2=NC=CC(C3=CC=CN=C3)=N2)=C1
CAS DataBase Reference :641569-94-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid is used in the preparation of (pyridinyl)-N-[(triazolyl)phenyl]pyrimidinamine derivatives and (pyridinyl)-N-[oxadiazolyl)phenyl]pyrimidinamine derivatives, and can be used in the detection of their activity as antileukemia agents (neoplastic stem cell leukemia). 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid is also a Nilotinib (N465300) intermediate, which might be useful in treatment of chronic myelogenous leukemia.

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