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ChemicalBook >> CAS DataBase List >> 4-AMINO-1,8-NAPHTHALIMIDE

4-AMINO-1,8-NAPHTHALIMIDE

4-AMINO-1,8-NAPHTHALIMIDE price.
  • $44 - $1022.42
  • Product name: 4-AMINO-1,8-NAPHTHALIMIDE
  • CAS: 1742-95-6
  • MF: C12H8N2O2
  • MW: 212.2
  • EINECS:217-110-1
  • MDL Number:MFCD00006921
  • Synonyms:4-Amino-1,8-naphthalenedicarbimide;4-Amino-1,8-naphthalenedicarboximide;4-Aminonaphthalene-1,8-dicarbimide;6-Amino-2,3-dihydro-1H-benzo[de]isoquinoline-1,3-dione;6-Amino-2H-benzo[de]isoquinoline-1,3-dione;4-Amino-1,8-naphthalimide,98%;6-amino-1h-benz(de)isoquinoline-3(2h)-dione ;6-amino-1h-benz[de]isoquinoline-3(2h)-dione
19 prices
Selected condition：
Brand
  • AK Scientific
  • Alfa Aesar
  • Alichem
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Cayman Chemical
  • Crysdot
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 5mg
  • 10mg
  • 20MG
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
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  • 10g
  • ManufacturerAK Scientific
  • Product number2616AL
  • Product description4-Amino-1,8-naphthalimide
  • Packaging250mg
  • Price$127
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ64358
  • Product description4-Amino-1,8-naphthalimide, 95%
  • Packaging100mg
  • Price$48.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ64358
  • Product description4-Amino-1,8-naphthalimide, 95%
  • Packaging1g
  • Price$201.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlichem
  • Product number1742956
  • Product description6-Amino-1H-benzo[de]isoquinoline-1,3(2H)-dione
  • Packaging5g
  • Price$925.41
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number1742956
  • Product description6-Amino-1H-benzo[de]isoquinoline-1,3(2H)-dione
  • Packaging10g
  • Price$1022.42
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0011463
  • Product description4-AMINO-1,8-NAPHTHALIMIDE 95.00%
  • Packaging20MG
  • Price$618.73
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA67151
  • Product description4-Amino-1,8-naphthalimide
  • Packaging250mg
  • Price$57.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA67151
  • Product description4-Amino-1,8-naphthalimide
  • Packaging500mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA67151
  • Product description4-Amino-1,8-naphthalimide
  • Packaging1g
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA67151
  • Product description4-Amino-1,8-naphthalimide
  • Packaging2g
  • Price$254
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA67151
  • Product description4-Amino-1,8-naphthalimide
  • Packaging5G
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18509
  • Product description4-amino-1,8-Naphthalimide ≥95%
  • Packaging250mg
  • Price$745
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18509
  • Product description4-amino-1,8-Naphthalimide ≥95%
  • Packaging100mg
  • Price$341
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18509
  • Product description4-amino-1,8-Naphthalimide ≥95%
  • Packaging50mg
  • Price$193
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18509
  • Product description4-amino-1,8-Naphthalimide ≥95%
  • Packaging10mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11232739
  • Product description4-AMINO-1,8-NAPHTHALIMIDE 97%
  • Packaging5g
  • Price$466
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2616AL 4-Amino-1,8-naphthalimide 250mg $127 2021-12-16 Buy
Alfa Aesar J64358 4-Amino-1,8-naphthalimide, 95% 100mg $48.65 2024-03-01 Buy
Alfa Aesar J64358 4-Amino-1,8-naphthalimide, 95% 1g $201.65 2024-03-01 Buy
Alichem 1742956 6-Amino-1H-benzo[de]isoquinoline-1,3(2H)-dione 5g $925.41 2021-12-16 Buy
Alichem 1742956 6-Amino-1H-benzo[de]isoquinoline-1,3(2H)-dione 10g $1022.42 2021-12-16 Buy
American Custom Chemicals Corporation CHM0011463 4-AMINO-1,8-NAPHTHALIMIDE 95.00% 20MG $618.73 2021-12-16 Buy
Biosynth Carbosynth FA67151 4-Amino-1,8-naphthalimide 250mg $57.5 2021-12-16 Buy
Biosynth Carbosynth FA67151 4-Amino-1,8-naphthalimide 500mg $90 2021-12-16 Buy
Biosynth Carbosynth FA67151 4-Amino-1,8-naphthalimide 1g $140 2021-12-16 Buy
Biosynth Carbosynth FA67151 4-Amino-1,8-naphthalimide 2g $254 2021-12-16 Buy
Biosynth Carbosynth FA67151 4-Amino-1,8-naphthalimide 5G $550 2021-12-16 Buy
Cayman Chemical 18509 4-amino-1,8-Naphthalimide ≥95% 250mg $745 2024-03-01 Buy
Cayman Chemical 18509 4-amino-1,8-Naphthalimide ≥95% 100mg $341 2024-03-01 Buy
Cayman Chemical 18509 4-amino-1,8-Naphthalimide ≥95% 50mg $193 2024-03-01 Buy
Cayman Chemical 18509 4-amino-1,8-Naphthalimide ≥95% 10mg $44 2024-03-01 Buy
Crysdot CD11232739 4-AMINO-1,8-NAPHTHALIMIDE 97% 5g $466 2021-12-16 Buy

Properties

Melting point :360 °C
Boiling point :352.04°C (rough estimate)
Density :1.105 g/mL at 25 °C(lit.)
vapor pressure :0Pa at 25℃
refractive index :1.6000 (estimate)
storage temp. :-20°C
solubility :Soluble in DMSO
form :Orange solid.
pka :9.53±0.20(Predicted)
color :Yellow to brown
Water Solubility :354mg/L at 25℃
LogP :1.08
CAS DataBase Reference :1742-95-6
EPA Substance Registry System :1H-Benz[de]isoquinoline-1,3(2H)-dione, 6-amino- (1742-95-6)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. 4-amino-1,8-Naphthalimide (4-ANI) is an inhibitor of PARP (IC50 = 180 nM). It blocks radiation-induced PARP in cancer cells, potentiating the cytotoxicity of γ-radiation, although it is not cytotoxic in the absence of radiation. 4-ANI is used to study the role of PARP activity in various cell systems.

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