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ChemicalBook >> CAS DataBase List >> Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate

Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate

Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate price.
  • $10 - $1280.66
  • Product name: Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
  • CAS: 161797-99-5
  • MF: C13H13NO3S
  • MW: 263.31
  • EINECS:605-268-8
  • MDL Number:MFCD03700424
  • Synonyms:ethyl 2-(4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate;Ethyl 2-(4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate;2-(4-hydroxyphenyl)-4-Methyl-5-Thiazolecarboxylicacid ethyl ester;5-Thiazolecarboxylic acid, 2-(4-hydroxyphenyl)-4-Methyl-, ethyl ester;Intermediates of Febuxostat;Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate Ethyl 2-(4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate;2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate;Febuxostat Descyano Hydroxy Ethyl Ester
28 prices
Selected condition：
Brand
  • AK Scientific
  • Alfa Aesar
  • Alichem
  • Ambeed
  • American Custom Chemicals Corporation
  • Ark Pharm
  • BLDpharm
  • Chemcia Scientific
  • Chemenu
  • Crysdot
  • Medical Isotopes, Inc.
  • SynChem
  • TRC
Package
  • 250mg
  • 1g
  • 2.5g
  • 5g
  • 10g
  • 25g
  • 100g
  • 250g
  • ManufacturerAK Scientific
  • Product numberX8013
  • Product descriptionEthyl2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
  • Packaging100g
  • Price$316
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberH52223
  • Product descriptionEthyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate, 97%
  • Packaging1g
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberH52223
  • Product descriptionEthyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate, 97%
  • Packaging5g
  • Price$439
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number161797995
  • Product descriptionEthyl2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
  • Packaging25g
  • Price$182
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number161797995
  • Product descriptionEthyl2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
  • Packaging100g
  • Price$458.85
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA164535
  • Product descriptionEthyl2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 98%
  • Packaging1g
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA164535
  • Product descriptionEthyl2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 98%
  • Packaging5g
  • Price$22
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA164535
  • Product descriptionEthyl2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 98%
  • Packaging10g
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA164535
  • Product descriptionEthyl2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 98%
  • Packaging25g
  • Price$81
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA164535
  • Product descriptionEthyl2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 98%
  • Packaging100g
  • Price$209
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0068815
  • Product descriptionETHYL 2-(4-HYDROXYPHENYL)-4-METHYLTHIAZOLE-5-CARBOXYLATE 95.00%
  • Packaging1G
  • Price$1280.66
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000219189
  • Product descriptionEthyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 98%
  • Packaging1g
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000219189
  • Product descriptionEthyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 98%
  • Packaging5g
  • Price$23
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000219189
  • Product descriptionEthyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 98%
  • Packaging10g
  • Price$37
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000219189
  • Product descriptionEthyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 98%
  • Packaging25g
  • Price$74
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000219189
  • Product descriptionEthyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 98%
  • Packaging100g
  • Price$187
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X8013 Ethyl2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 100g $316 2021-12-16 Buy
Alfa Aesar H52223 Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate, 97% 1g $110 2021-12-16 Buy
Alfa Aesar H52223 Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate, 97% 5g $439 2021-12-16 Buy
Alichem 161797995 Ethyl2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 25g $182 2021-12-16 Buy
Alichem 161797995 Ethyl2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 100g $458.85 2021-12-16 Buy
Ambeed A164535 Ethyl2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 98% 1g $11 2021-12-16 Buy
Ambeed A164535 Ethyl2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 98% 5g $22 2021-12-16 Buy
Ambeed A164535 Ethyl2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 98% 10g $40 2021-12-16 Buy
Ambeed A164535 Ethyl2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 98% 25g $81 2021-12-16 Buy
Ambeed A164535 Ethyl2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 98% 100g $209 2021-12-16 Buy
American Custom Chemicals Corporation CHM0068815 ETHYL 2-(4-HYDROXYPHENYL)-4-METHYLTHIAZOLE-5-CARBOXYLATE 95.00% 1G $1280.66 2021-12-16 Buy
Ark Pharm P000219189 Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 98% 1g $10 2021-12-16 Buy
Ark Pharm P000219189 Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 98% 5g $23 2021-12-16 Buy
Ark Pharm P000219189 Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 98% 10g $37 2021-12-16 Buy
Ark Pharm P000219189 Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 98% 25g $74 2021-12-16 Buy
Ark Pharm P000219189 Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 98% 100g $187 2021-12-16 Buy

Properties

Melting point :180 ºC
Boiling point :426.8±55.0 °C(Predicted)
Density :1.274
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO (Slightly), Methanol (Very Slightly)
form :Solid
pka :8.56±0.15(Predicted)
color :Off-White
InChI :InChI=1S/C13H13NO3S/c1-3-17-13(16)11-8(2)14-12(18-11)9-4-6-10(15)7-5-9/h4-7,15H,3H2,1-2H3
InChIKey :LOCYSKNNFCGDTR-UHFFFAOYSA-N
SMILES :S1C(C(OCC)=O)=C(C)N=C1C1=CC=C(O)C=C1
CAS DataBase Reference :161797-99-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate is used in the synthesis of the major metabolites of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.