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ChemicalBook >> CAS DataBase List >> 4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl ester

4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl ester

4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl ester price.
  • $153 - $1780
  • Product name: 4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl ester
  • CAS: 131666-45-0
  • MF: C15H15N3O4
  • MW: 301.3
  • EINECS:-0
  • MDL Number:
  • Synonyms:4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl ester;Defluoro 8-Hydroxy FluMazenil (IMpurity);Ethyl 8-hydroxy-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate;Flumazenil EP Impurity B;Flumazenil impurity B (EP);Flumazenil Impurity 2(Flumazenil EP Impurity B);Flumazenil impurity B CRS;Ethyl 8-hydroxy-5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate
4 prices
Selected condition：
Brand
  • AK Scientific
  • Sigma-Aldrich
  • TRC
Package
  • 5mg
  • 20mg
  • 2.5mg
  • y0000335
  • ManufacturerAK Scientific
  • Product number6319DT
  • Product descriptionEthyl8-hydroxy-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
  • Packaging5mg
  • Price$329
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberY0000335
  • Product descriptionFlumazenil impurity B European Pharmacopoeia (EP) Reference Standard
  • Packagingy0000335
  • Price$153
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number1273820
  • Product descriptionFlumazenil impurity B
  • Packaging20mg
  • Price$1780
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberD228740
  • Product descriptionDefluoro8-HydroxyFlumazenil(Impurity)
  • Packaging2.5mg
  • Price$160
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 6319DT Ethyl8-hydroxy-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 5mg $329 2021-12-16 Buy
Sigma-Aldrich Y0000335 Flumazenil impurity B European Pharmacopoeia (EP) Reference Standard y0000335 $153 2024-03-01 Buy
Sigma-Aldrich 1273820 Flumazenil impurity B 20mg $1780 2024-03-01 Buy
TRC D228740 Defluoro8-HydroxyFlumazenil(Impurity) 2.5mg $160 2021-12-16 Buy

Properties

Boiling point :588.6±50.0 °C(Predicted)
Density :1.42±0.1 g/cm3(Predicted)
pka :8.54±0.20(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P313 Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Defluoro 8-hydroxy Flumazenil is an impurity of Flumazenil (F500450), a benzodiazepine antagonist that can prevent or abolish (at the receptor level) the effects of a benzodiazepine.

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