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ChemicalBook >> CAS DataBase List >>Vincristine sulfate

Vincristine sulfate suppliers

Vincristine sulfate

CAS:
2068-78-2
MF:
C46H58N4O14S
MW:
923.04

Properties

Melting point:
300 °C
Boiling point:
273-281 °C
alpha 
D26 +8.5° (c = 0.8)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
methanol: soluble20mg/mL
form 
lyophilized powder
color 
white to off-white
Water Solubility 
>=1 g/100 mL at 24 ºC
BRN 
3924631
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
InChIKey
AQTQHPDCURKLKT-HSMPTBRCNA-N

Safety Information

Symbol(GHS) 
GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08
Signal word 
Danger
Hazard statements 
H300-H341-H361fd
Precautionary statements 
P202-P264-P270-P280-P301+P310-P405
Hazard Codes 
T
Risk Statements 
61-36/37/38-63-23/24/25-68-62-25
Safety Statements 
22-24/25-53-45-37/39-26-36/37/39-36/37
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
3
RTECS 
OH6340000
8-10
HazardClass 
6.1(a)
PackingGroup 
II
HS Code 
29399990
Toxicity
LD50 intraperitoneal in mouse: 3mg/kg

Use

Vincristine sulfate is available as a 1-mg/mL solution in 1-,2-, and 5-mL vials for IV administration in acute leukemiaand as part of a multidrug regime for Hodgkin’s and neuroblastoma, Ewing sarcoma, Wilms tumor, soft tissuesarcoma, testicular cancer, liver cancer, and head and neckcancers. It has also been utilized in treating pediatric cancer.Vincristine is highly protein bound (75%) and may also bindto platelets that contain large amounts of tubulin. Numerousmetabolites have been detected and several have been identified,one of which is the 4-O-desacetyl derivative. The metabolismthat does occur is believed to largely be mediatedby CYP3A. Elimination occurs primarily in the bile with aterminal elimination half-life of 23 to 85 hours. The mostcommonly seen toxicity for vincristine is a dose-limitingneurotoxicity caused by effects on axonal microtubules.Symptoms are variable and include peripheral neuropathy,ataxia, seizure, bone pain, and coma. Constipation is also acommonly seen toxicity, and laxatives may be used prophylactically.Other toxicities include alopecia, skin rash, mildmyelosuppression, secretion of antidiuretic hormone,azospermia, and amenorrhea.

346 supplier list of "Vincristine sulfate"

Vincristine Sulphate Vincristine Sulphate 2Photos

$1.00/ 1g

  • Product Name:Vincristine Sulphate
  • Products Intro:Purity: 99|Package: 1g;1.00;USD
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Fluorouracil,Entecavir,Sofosbuvir,Vinblastine sulfate

$0.00-0.00 / 1Kg

  • Product Name:Vincristine Sulfate
  • Products Intro:Purity: 99%;USP/EP/CP | Package: 1Kg;|5Kg;|25Kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: 5-bromo-1h-indazole-3-carboxylic acid,1,1′-(Azodicarbonyl)dipiperidine,2,4-Difluorobenzaldehyde,1H-Indazole-3-acetic acid,5-Bromo-1H-indazole-3-acetic acid

$20.00/ 1kg

  • Product Name:Vincristine sulfate
  • Products Intro:Purity: 99% | Package: 1kg;20USD
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Pharmaceutical intermediates,Peptides,Organic Chemical,Sarm Product,Pharmaceutical Chemical

$25.00/ 1kg

  • Product Name:Vincristine Sulfate
  • Products Intro:Purity: 99%|Package: 1kg;25.00;USD
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Chemical Raw Materials,Pharmaceutical Intermediates,Cosmetic Materials,Food Additive,Organic Intermediate

$0.00/ 25kg

  • Product Name:Vincristine sulfate
  • Products Intro:Purity: 99% | Package: 25kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: cesium,lithium,Monomethylamine hydrochloride,2-phenylacetamide,Lead acetate
Vincristine Sulfate Vincristine Sulfate 2Photos

$0.00/ 1g

  • Product Name:Vincristine Sulfate
  • Products Intro:Purity: More Than 99% | Package: 1g
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Pharmaceutical Chemicals,Apis,Pharmaceutical Intermediates,Electronic Chemicals,OLED Intermediates
  • Product Name:Vincristine Sulfate
  • Products Intro:Purity: 98% Min. | Package: 1G;1KG;100KG
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: 1159983-30-8,89466-59-1,149739-51-5,104901-79-3,10541-83-0
  • Product Name:Vincristine sulfate
  • Products Intro:Purity: 99% | Package: 25KG;5KG;1KG
  • Company Type: Trader
  • Country/Region: CHINA

$1.00/ 1kg

  • Product Name:Vincristine sulfate
  • Products Intro:Purity: 95%-99% | Package: 1kg;1USD
  • Company Type: Reagent
  • Country/Region: CHINA
  • Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
  • Product Name:Vincristine Sulfate
  • Products Intro:Purity: >95%,98%,99% | Package: From mgs to grams,up to Kgs | CustNote: Can be customized in bulk scale
  • Company Type: Reagent
  • Country/Region: CHINA
  • Main Products: Mogroside V,Methysticin,Sarsasapogenin,20(R)-Ginsenoside Rg3,Ginsenoside CK
You can find Vincristine sulfate suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

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