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ChemicalBook >> CAS DataBase List >>Losartan potassium

Losartan potassium suppliers

Losartan potassium

CAS:
124750-99-8
MF:
C22H23ClKN6O
MW:
462.01

Properties

Melting point:
263-265°C
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Freely soluble in water and in methanol, slightly soluble in acetonitrile.
form 
powder or crystals
color 
Off-white
Merck 
14,5583
BRN 
5845770
BCS Class
1
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
InChI
InChI=1S/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1
InChIKey
OXCMYAYHXIHQOA-UHFFFAOYSA-N
SMILES
C1(C=CC=CC=1C1=CC=C(CN2C(CO)=C(Cl)N=C2CCCC)C=C1)C1=NN=NN1[K]
CAS DataBase Reference
124750-99-8(CAS DataBase Reference)

Safety Information

Symbol(GHS) 
GHS hazard pictograms
GHS07
Signal word 
Warning
Hazard statements 
H315-H319-H335
Precautionary statements 
P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c
Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
WGK Germany 
3
RTECS 
NI6755100
HS Code 
2933290000

Use

Losartan potassium is the first potent and selective non-peptide angiotensin II (AT II) AT1 receptor antagonist introduced to the market as a once-daily oral antihypertensive. It is efficacious and long lasting in controlling blood pressure in spontaneous hypertensive rats, in patients with essential hypertension in addition to those patients with renal impairment. Since losartan functions by competitive antagonism at the level of receptor, which represents the most direct way of selectively inhibiting the renin-angiotensin system (RAS) independent of the source of AT II, its use has been reported to be free of the coughing side effect exhibited by the ACE inhibitors. In contrast to calcium channel blockers, losartan does not appear to cause ankle edema, headache and tachycardia. It is also reported to be in clinical trials for the treatment of heart failure. Other reports indicate that losartan may have potential efficacy as an anxiolytic, an antiglaucoma agent, in addition to in providing protection against stroke and in preventing the myointimal proliferative response of the vascular wall after coronary angioplasty and surgery.

686 supplier list of "Losartan potassium"

  • Product Name:Losartan Potassium
  • Products Intro:Purity: 99% | Package: 1g,10g,100g,500g,1kg,25kg,100kg,500kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: quinine series,urolithin a,Retinoic acid,Nicotinamide,Hyaluronic acid
Losartan Potassium Losartan Potassium 2Photos

$0.00-0.00 / 1KG

  • Product Name:Losartan Potassium
  • Products Intro:Purity: USP|Package: 1KG;0.00;USD|25KG;0.00;USD|100KG;0.00;USD
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: APIs,pharmaceutical intermediates,health and food supplements,cosmetic raw materials,herbal extracts

$50.00/ 1kg

  • Product Name:Losartan potassium
  • Products Intro:Purity: 99% | Package: 1kg;50USD
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Pharmaceutical intermediates,Peptides,Organic Chemical,Sarm Product,Pharmaceutical Chemical
Losartan Potassium Losartan Potassium 2Photos

$0.00/ 1kg

  • Product Name:Losartan Potassium
  • Products Intro:Purity: 99% | Package: 1kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:Losartan potassium
  • Products Intro:Purity: 99% | Package: 25KG;5KG;1KG
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:Losartan potassium
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:Losartan potassium
  • Products Intro:Purity: 98% HPLC | Package: 5G;10G;25G;50G;100G;250G;1KG
  • Company Type: Reagent
  • Country/Region: CHINA
  • Product Name:Losartan potassium
  • Products Intro:Purity: USP BP EP | Package: 1KG;5USD
  • Company Type: Reagent
  • Country/Region: CHINA

$7.00/ 1kg

  • Product Name: Losartan potassium
  • Products Intro:Purity: 99% | Package: 1kg;7USD
  • Company Type: Reagent
  • Country/Region: CHINA
  • Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
  • Product Name:Losartan Potassium
  • Company Type: Service provider
  • Country/Region: CHINA
  • Main Products: UDDA
You can find Losartan potassium suppliers, manufacturers, and distributors from countries such as China, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

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