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ChemicalBook--->CAS DataBase List--->180084-26-8

180084-26-8

180084-26-8 Structure

180084-26-8 Structure
IdentificationBack Directory
[Name]

SB 224289 HYDROCHLORIDE
[CAS]

180084-26-8
[Synonyms]

SB 224289A
1'-methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo[2,3-f]indole-3,4'-piperidine] hydrochloride
SB-224289A, 1μ-Methyl-5-[[2μ-methyl-4μ-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo[2,3-f]indole-3,4μ-piperidine] hydrochloride
[Molecular Formula]

C32H32N4O3HCl
[MDL Number]

MFCD03788209
[MOL File]

180084-26-8.mol
Chemical PropertiesBack Directory
[storage temp. ]

Store at RT
[solubility ]

Soluble to 10 mM in DMSO with gentle warming
[form ]

Powder
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313
[Safety Statements ]

22-24/25
Hazard InformationBack Directory
[Uses]

SB 224289A is a 5-HT1B antagonist.
[Definition]

ChEBI: SB 224289 hydrochloride is a hydrochloride that is the monohydrochloride salt of SB 224289. Selective 5-HT1B receptor antagonist (pKi = 8.2). Displays >60-fold selectivity over 5-HT1D, 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A and 5-HT2C receptors in radioligand binding and functional assays. Centrally active following oral administration in vivo. It has a role as a prodrug and a serotonergic antagonist. It contains a SB 224289(1+).
[storage]

Room temperature
Spectrum DetailBack Directory
[Spectrum Detail]

SB 224289 HYDROCHLORIDE(180084-26-8)1HNMR
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