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Shield-1

Shield-1 ??? ???
?? ??:
914805-33-7
???:
Shield-1
???(??):
Shld-1;Shield-1;Shield-1 Tosylate;SHLD-1;SHIELD 1;SHIELD1;(R)-3-(3,4-Dimethoxyphenyl)-1-(3-(2-morpholinoethoxy)phenyl)propyl (S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carboxylate;(1R)-3-(3,4-dimethoxyphenyl)-1-{3-[2-(morpholin-4-yl)ethoxy]phenyl}propyl (2S)-1-[(2S)-2-(3,4,5-trimethoxyphenyl)butanoyl]piperidine-2-carboxylate;FK506-binding protein,inhibit,Shield 1,high-affinity ligand,Shield-1,destabilization domain,Inhibitor,Shield1,Shld 1,Shld1,HEK293,FKBP,NIH3T3,Shld-1;(1R)-3-(3,4-Dimethoxyphenyl)-1-[3-[2-(4-morpholinyl)ethoxy]phenyl]propyl (2S)-1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-2-piperidinecarboxylate;2-Piperidinecarboxylic acid, 1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-, (1R)-3-(3,4-dimethoxyphenyl)-1-[3-[2-(4-morpholinyl)ethoxy]phenyl]propyl ester, (2S)-
CBNumber:
CB54201095
???:
C42H56N2O10
??? ??:
748.9
MOL ??:
914805-33-7.mol

Shield-1 ??

???
54-55o C
?? ?
837.6±65.0 °C(Predicted)
??
1.168±0.06 g/cm3(Predicted)
?? ??
Hygroscopic, Refrigerator, under inert atmosphere
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?????(?? ???), ???(?? ???)
?? ?? (pKa)
6.43±0.10(Predicted)
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Shield-1 C??? ??, ??, ??

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Shield 1, an AKT inhibitor, potently inhibits proliferation as well as induces apoptosis in prostate cancer cell lines.

Shield-1 ?? ?? ? ???

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Shield-1 ?? ??

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