A,A'-????
|
|
A,A'-???? ??
- ???
- 70-73 °C(lit.)
- ?? ?
- 273 °C(lit.)
- ??
- 1.1668 (rough estimate)
- ???
- 0.584Pa at 25℃
- ???
- 1.4820 (estimate)
- ???
- 121 °C
- ?? ??
- room temp
- ???
- 5.5g/L
- ??? ??
- ??? ??
- ?? ?? (pKa)
- pK1:-0.52(+2);pK2:4.352(+1) (20°C)
- ??
- ???? ?? ??
- ??????(pH)
- 7.5 (5g/l, H2O, 25℃)
- ??
- ??? ??
- ???
- 5.5g/L 22℃
- Merck
- 14,3347
- BRN
- 113089
- ???
- ????. ?? ???? ??? ?? ???? ???? ????. ?? ??? ? ????.
- InChIKey
- ROFVEXUMMXZLPA-UHFFFAOYSA-N
- CAS ??????
- 366-18-7(CAS DataBase Reference)
??
- ?? ? ?? ??
| ??? ?? | T,Xi | ||
|---|---|---|---|
| ?? ???? ?? | 25-36/37/38-20/21-23/24/25-21 | ||
| ????? | 36/37-45-36/37/39-26 | ||
| ????(UN No.) | UN 2811 6.1/PG 3 | ||
| WGK ?? | 3 | ||
| RTECS ?? | DW1750000 | ||
| F ?????? | 8 | ||
| ?? ?? ?? | Irritant | ||
| TSCA | Yes | ||
| ?? ?? | 6.1 | ||
| ???? | III | ||
| HS ?? | 29333999 | ||
| ?? ?? ??? | 366-18-7(Hazardous Substances Data) | ||
| ?? | LD50 i.p. in mice: 200 mg/kg (Grady) | ||
| ???? ?? | KE-12238 |
A,A'-???? C??? ??, ??, ??
??
?? ?? ?? ??(?? ??? ?? ???-??? ???). ??? 69.5℃, ??? 272.5℃. ???, ???, ??, ????? ?? ???. ?? ? ? ???. ?? ?? ??? ?(Ⅱ)??? ?? [FeⅡ(C10H8N2)3]X2? ??? ?? ??? ???, ?(Ⅲ) ???? ??? ???? ???.??
?(Ⅱ)? ?? ?? ????? ????. ?(Ⅱ)? pH 3~9?? ??? ????, ?? ?? ?? 522mμ, ??? ?? ?????. ?? ?? 0.1~4ppm. [FeⅡ(C10H8N2)3]X2? ???? ???? [FeⅢ(C10H8N2)3]X3? ??. ? ??? ????? ??? ?? ?? ????? ????.??? ??
White to light red crystalline powder. Soluble in ethanol, ether, benzene, chloroform and petroleum ether, 1 part of this product is about 200 parts of water.??
2,2'-bipyridine acts as a bidentate chelating ligand which form complexes with transition metal ions and shows antifungal, antibacterial and antiviral activity. It is used for the colorimetric determination of iron as well as oxidation reduction indicators to confirm the presence of ferrous ion in soils. It forms complexes with ruthenium and platinum, exhibit intense luminescence, which may have practical applications. Copper(I) bipyridine complexes involved in the oxidation of alcohols under aerobic conditions.?? ??
2,2'-bipyridine is synthesized by the reaction of pyridine with ferric chloride. Take 70g of anhydrous pyridine and mix with 13g of anhydrous ferric chloride, heat and react at 300℃ in a sealed tube for about 35h. After cooling, the reactant solidified into red-black crystals, the sealing tube was opened, and the red-black solution of the solid was washed out with a small amount of hot water. The oily impurities were removed by extraction with ether. After neutralization with sodium bicarbonate, excess pyridine was removed by heating with steam. The mixture was then made strongly basic, and the 2,2'-bipyridine was distilled off with steam.??
ChEBI: 2,2'-bipyridine is a bipyridine in which the two pyridine moieties are linked by a bond between positions C-2 and C-2'. It has a role as a ferroptosis inhibitor and a chelator.?? ??
A large number of complexes of 2,2'-bipyridine have been described.It binds metals as a chelating ligand, forming a 5-membered chelate ring.?? ??
2,2′-Bipyridyl, is a symmetrical bipyridine commonly used as a neutral ligand for complexation with metal ions. The molecule is planar with trans-conformation and crystallizes in the monoclinic crystal system.Safety Profile
Poison by ingestion,subcutaneous, and intraperitoneal routes. Experimentalteratogenic data. Questionable carcinogen withexperimental tumorigenic data. Mutation data reported.When heated to decomposition it emits toxic fumes ofNOx.Purification Methods
2,2'-Bipyridyl crystallises from hexane, or EtOH, or (after charcoal treatment of a CHCl3 solution) from pet ether. Also, it precipitates from a concentrated solution in EtOH by addition of H2O. Dry it in a vacuum over P2O5. It can be further purified by chromatography on Al2O3 or by sublimation. UV (EtOH): at 280nm (log 4.13). max [Airoldi et al. J Chem Soc, Dalton Trans 1913 1986, Beilstein 23 H 199, 23/8 V 16.]A,A'-???? ?? ?? ? ???
???
α-???
????????
Anhydrous pyridine
5-??-2,2'-????
5,5'-DIMETHYL-2,2'-DIPYRIDYL
2-??????
??????
?????-2-?????97
?? ??
A,A'-???? ?? ??
???( 777)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Shanghai Bojing Chemical Co.,Ltd. | +86-86-02137122233 +8613795318958 |
bj1@bj-chem.com | China | 299 | 55 |
| Wuhan Bright Chemical Co., Ltd | +86-02785804899 +86-15071395570 |
alice@brightchemical.com.cn | China | 93 | 58 |
| Shanghai Yongzeng Technology Co.,Ltd | +86-021-65281118 +86-13818947575 |
sales@yongzchem.com | China | 138 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 |
abby@weibangbio.com | China | 8810 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-18789408387 |
1057@dideu.com | China | 3959 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5857 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 |
sales@myuchem.com | China | 7629 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5889 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20284 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 |
sales02@sdzhonghuimaterial.com | China | 983 | 58 |
A,A'-???? ?? ??:
??? ????? ?????? ??(III) 2,6-??? 4,5-???????-9-one (2,2'-?????)-4,4'-??????, ???? (1:2) 2,2′:6′,2′′-???? 4,4'-???? ??????? ???? ???? ??? ???? ???? ????(???) 2,4''-???? A,A'-????
2-Chloro-3-cyanopyridine
DIPIPERIDINOMETHANE
4,4'-DIMETHYL-2,2'-DIPYRIDYL,4,4'-Dimethyl-2,2'-dipyridyl ,98%,4,4'-DIMETHYL-2,2'-DIPYRIDYL, SUBLIMED &
2,2'-DIPYRIDYL-4,4'-DICARBOXYLIC ACID