ピロりん酸テトラベンジル
ピロりん酸テトラベンジル 物理性質(zhì)
- 融點 :
- 63-66 °C (lit.)
- 沸點 :
- 601.6±55.0 °C(Predicted)
- 比重(密度) :
- 1.289±0.06 g/cm3(Predicted)
- 蒸気圧:
- 0.001Pa at 140℃
- 貯蔵溫度 :
- -20°C
- 溶解性:
- Chloroform (Slightly), Methanol (Slightly)
- 外見 :
- 粉末または結(jié)晶性粉末
- 色:
- ホワイトからオフホワイト
- 水溶解度 :
- 水にわずかに溶ける。
- Sensitive :
- Moisture Sensitive
- BRN :
- 2068292
- InChI:
- InChI=1S/C28H28O7P2/c29-36(31-21-25-13-5-1-6-14-25,32-22-26-15-7-2-8-16-26)35-37(30,33-23-27-17-9-3-10-18-27)34-24-28-19-11-4-12-20-28/h1-20H,21-24H2
- InChIKey:
- NSBNXCZCLRBQTA-UHFFFAOYSA-N
- SMILES:
- P(=O)(OCC1C=CC=CC=1)(OCC1C=CC=CC=1)OP(=O)(OCC1C=CC=CC=1)OCC1C=CC=CC=1
- CAS データベース:
- 990-91-0(CAS DataBase Reference)
安全性情報
- リスクと安全性に関する聲明
- 危険有害性情報のコード(GHS)
| 主な危険性 |
C |
|
|
| Rフレーズ |
34 |
|
|
| Sフレーズ |
26-36/37/39-45 |
|
|
| RIDADR |
UN 3261 8/PG 2 |
|
|
| WGK Germany |
3 |
|
|
| F |
10-21 |
|
|
| 國連危険物分類 |
8 |
|
|
| 容器等級 |
II |
|
|
| HSコード |
29209090 |
|
|
| 絵表示（GHS） |
|
| 注意喚起語 |
危険 |
| 危険有害性情報 |
| コード |
危険有害性情報 |
危険有害性クラス |
區(qū)分 |
注意喚起語 |
シンボル |
P コード |
| H314 |
重篤な皮膚の薬傷?眼の損傷 |
皮膚腐食性/刺激性 |
1A, B, C |
危険 |
|
P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501 |
|
| 注意書き |
| P260 |
粉じん/煙/ガス/ミスト/蒸気/スプレーを吸入しないこ と。 |
| P280 |
保護手袋/保護衣/保護眼鏡/保護面を著用するこ と。 |
| P303+P361+P353 |
皮膚（または髪）に付著した場合：直ちに汚染された衣 類をすべて脫ぐこと/取り除くこと。皮膚を流水/シャワー で洗うこと。 |
| P305+P351+P338 |
眼に入った場合：水で數(shù)分間注意深く洗うこと。次にコ ンタクトレンズを著用していて容易に外せる場合は外す こと。その後も洗浄を続けること。 |
| P363 |
汚染された衣類を再使用す場合には洗濯をすること。 |
|
ピロりん酸テトラベンジル 価格
もっと(11)
| メーカー |
製品番號 |
製品説明 |
CAS番號 |
包裝 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式會社(wako)
|
W01AFAL09083 |
ピロりん酸テトラベンジル, 98%
Tetrabenzyl pyrophosphate, 98% |
990-91-0 |
1g |
￥46800 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式會社(wako)
|
W01AFAL09083 |
ピロりん酸テトラベンジル, 98%
Tetrabenzyl pyrophosphate, 98% |
990-91-0 |
5g |
￥201700 |
2024-03-01 |
購入 |
|
東京化成工業(yè)
|
P1223 |
ピロりん酸テトラベンジル >98.0%(HPLC)
Tetrabenzyl Pyrophosphate
>98.0%(HPLC) |
990-91-0 |
1g |
￥8700 |
2023-06-01 |
購入 |
|
富士フイルム和光純薬株式會社(wako)
|
43675-1A |
Tetrabenzyl pyrophosphate |
990-91-0 |
1g |
￥23320 |
2024-07-01 |
購入 |
|
Sigma-Aldrich Japan
|
418633 |
ピロリン酸テトラベンジル 98%
Tetrabenzyl pyrophosphate 98% |
990-91-0 |
1g |
￥9160 |
2024-03-01 |
購入 |
ピロりん酸テトラベンジル 化學特性,用途語,生産方法
外観
白色～うすい黃褐色、結(jié)晶性粉末～粉末
使用上の注意
アルゴン封入
化學的特性
White Solid
特性
Tetrabenzyl pyrophosphate and diphenylphosphinic anhydride, with two phosphoryl groups (P O) as ligating sites, can be used as novel ionophores to make Pb2+-selective membrane electrodes. A good result was obtained with tetrabenzyl pyrophosphate, and the electrode based on this ionophore and bis(1-butylpentyl) adipate as a solvent mediator in a poly(vinyl chloride) membrane matrix exhibited a near-Nernstian response to Pb2+ in the concentration range of 1×10?5–1×10?2 M with a slope of 28.7 mV per concentration decade in a solution containing 0.1 M Mg(NO3)2. Tetrabenzyl pyrophosphate showed the best response to Pb2+, almost free from interference by other metal cations. By adding the ionic additive potassium tetrakis(p-chlorophenyl)borate (KTpClPB; 40 mol% relative to tetrabenzyl pyrophosphate), a drastic change occurred in the electrode response, showing a monovalent species probably due to the formation of PbA+, where A stands for anions present in the sample solution, and decreased the selectivity of the electrode to other metal cations[1].
使用
Tetrabenzyl pyrophosphate is used in the preparation of phosphoryl derivatives of shikimic acid in the presence of LDA. It is used in the preparation of dibenzyl phosphoro fluoridate in the presence of cesium fluoride as a catalyst. It is also used as a precursor in pharmaceuticals and involved in the phosphorylation of inositol derivatives.
製造方法
The production of tetrabenzyl pyrophosphate by the action of acyl chlorides on dibenzyl hydrogen phosphate, and a novel reaction of tetraphenyl pyrophosphate.
Preparation of Tetrabenzyl Pyrophosphate: A flask fitted with a nitrogen inlet, overhead stirrer, teflon-coated thermocouple probe, and pressure-equalizing addition funnel was charged with 350 milliliters of dry (water content ≦50 μg/mL), peroxide-free tetrahydrofuran, followed by 50.0 grams (174 millimoles) of dibenzylphosphoric acid (DBP), and the resulting mixture was stirred until the solid dissolved (about 10-15 minutes). A solution of 18.9 grams (91.6 millimoles) of dicyclohexylcarbodiimide (DCC) in 215 milliliters of THF was added from the addition funnel to a stirred, cooled (water-bath) solution of DBP at a rate to maintain the temperature at about 20°-25° C. The reaction is slightly exothermic and the addition took about 30 minutes. Within minutes, a precipitate of dicyclohexylurea formed in the mixture. Stirring was continued for about 2 hours at 20°-25° C. The reaction was monitored by HPLC assay using VYDAC C-18 (300A, 4.6×250 mm) column with water (0.02M KH2PO4) acetonitrile as eluent. The reaction was complete in about 1 hour (assay showing <2 percent unreacted DBP). The mixture was then filtered while excluding moisture to remove dicyclohexylurea. The filter cake was washed with two 25 milliliter portions of THF. The solution when assayed by HPLC showed 45.9 grams (98 percent) yield of tetrabenzyl pyrophosphate (TBPP) in 620 milliliters of THF (0.137M). The filtrate was then stored at 0° C. with exclusion of moisture until the next step.
ピロりん酸テトラベンジル 上流と下流の製品情報
原材料
準備製品
ピロりん酸テトラベンジル 生産企業(yè)
Global( 320)Suppliers
| 名前 |
電話番號 |
電子メール |
國籍 |
製品カタログ |
優(yōu)位度 |
|
Hefei TianRui Pharmaceutical Chemical Co., Ltd.
|
+86-0551-68665055 +86-+86-18616906106
|
sales@trywchem.com |
China |
148 |
58 |
|
Wuhan Circle Star Chem-medical Technology Co.,Ltd
|
027-85558552 +undefined13437180835
|
Janel@circlestar-chem.com |
China |
1000 |
58 |
|
Hebei Weibang Biotechnology Co., Ltd
|
+8615531157085
|
abby@weibangbio.com |
China |
8803 |
58 |
|
Hebei Mujin Biotechnology Co.,Ltd
|
+86 13288715578 +8613288715578
|
sales@hbmojin.com |
China |
12825 |
58 |
|
Hebei Chuanghai Biotechnology Co,.LTD
|
+86-13131129325
|
sales1@chuanghaibio.com |
China |
5881 |
58 |
|
Frapp's ChemicalNFTZ Co., Ltd.
|
+86 (576) 8169-6106
|
sales@frappschem.com |
China |
880 |
50 |
|
Capot Chemical Co.,Ltd.
|
+86-（0）57185586718 +86-13336195806
|
sales@capot.com |
China |
29685 |
60 |
|
Shanghai Daken Advanced Materials Co.,Ltd
|
+86-371-66670886
|
info@dakenam.com |
China |
19875 |
58 |
|
Henan Tianfu Chemical Co.,Ltd.
|
+86-0371-55170693 +86-19937530512
|
info@tianfuchem.com |
China |
21632 |
55 |
|
Shanghai Yingrui Biopharma Co., Ltd.
|
+86-21-33585366 - 03@
|
sales03@shyrchem.com |
CHINA |
738 |
60 |
ピロりん酸テトラベンジル スペクトルデータ(1HNMR、FT-IR、IR)
990-91-0(ピロりん酸テトラベンジル)キーワード:
- 990-91-0
- TETRABENZYL PYROPHOSPHATE
- Tetrabenzyl pyrophosphate, tech.
- Pyrophosphoric acid tetrabenzyl ester, Tetrabenzyl diphosphate
- Bis(phenylmethoxy)phosphoryl bis(phenylmethyl) phosphate
- Benzyl Pyrophosphate
- Diphosphoric Acid P,P,P',P'-Tetrakis(phenylMethyl) Ester
- Tetrabenzyl yrophosphate
- Tetrabenzyl pyrophosphate Pyrophosphoric acid tetrabenzyl ester
- Tetrabenzyl pyrophosphate 98%
- dibenzyl {[bis(benzyloxy)phosphoryl]oxy}phosphonate
- Bis(phenylmethox
- yrophosphoric acid tetrabenzyl ester
- TetrabenzylPyrophosphate>
- Tetrabenzyl pyrophosphate, 99%, for synthesis
- TetrabenzyL
- Tetrabenzylpyrophosphate (TBPP)
- TETRABENZYL PYROPHOSPHATE 990-91-0
- Creatine Phosphate Impurity 21（Tetrabenzyl Diphosphate）
- Fosaprepitant Impurity S
- Tetrabenzyl
Pyrpophosphate
- dibenzyl bis(phenylmethoxy)phosphoryl phosphate
- PYROPHOSPHORIC ACID TETRABENZYL ESTER
- TETRABENZYL DIPHOSPHATE
- Tetracyl pyrophosphate
- P,P,P',P'-Tetrakis(phenylmethyl) (diphosphate)
- Tetrabenzyl Pyrophosphte
- C2gH2gO7P2
- ピロりん酸テトラベンジル
- 二りん酸テトラベンジル
- ピロりん酸テトラベンジル, 98%
- テトラベンジルピロホスフェート
- りん酸化剤
- りん酸化剤＆ホスホロチオエート化剤
- 保護剤，りん酸化剤，縮合剤
- 生化學
- 有機合成化學
- ヌクレオシド，ヌクレオチド＆関連試薬