3-IODOBENZYL-GUANIDINE HEMISULFATE
3-IODOBENZYL-GUANIDINE HEMISULFATE 物理性質(zhì)
- 貯蔵溫度 :
- 2-8°C
- 溶解性:
- DMSO: 2 mg/ml; DMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml
- 外見 :
- A crystalline solid
- 色:
- White to off-white
安全性情報
- リスクと安全性に関する聲明
- 危険有害性情報のコード(GHS)
| WGK Germany |
3 |
|
|
| HSコード |
2909309090 |
|
|
| 絵表示（GHS） |
|
| 注意喚起語 |
警告 |
| 危険有害性情報 |
| コード |
危険有害性情報 |
危険有害性クラス |
區(qū)分 |
注意喚起語 |
シンボル |
P コード |
| H302 |
飲み込むと有害 |
急性毒性、経口 |
4 |
警告 |
|
P264, P270, P301+P312, P330, P501 |
| H315 |
皮膚刺激 |
皮膚腐食性/刺激性 |
2 |
警告 |
|
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
強い眼刺激 |
眼に対する重篤な損傷性/眼刺激 性 |
2A |
警告 |
|
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
呼吸器への刺激のおそれ |
特定標(biāo)的臓器毒性、単回暴露； 気道刺激性 |
3 |
警告 |
|
|
|
| 注意書き |
| P261 |
粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。 |
| P280 |
保護手袋/保護衣/保護眼鏡/保護面を著用するこ と。 |
| P301+P312 |
飲み込んだ場合：気分が悪い時は醫(yī)師に連絡(luò)する こと。 |
| P302+P352 |
皮膚に付著した場合：多量の水と石鹸で洗うこと。 |
| P305+P351+P338 |
眼に入った場合：水で數(shù)分間注意深く洗うこと。次にコ ンタクトレンズを著用していて容易に外せる場合は外す こと。その後も洗浄を続けること。 |
|
3-IODOBENZYL-GUANIDINE HEMISULFATE 価格
もっと(3)
| メーカー |
製品番號 |
製品説明 |
CAS番號 |
包裝 |
価格 |
更新時間 |
購入 |
|
Sigma-Aldrich Japan
|
I9890 |
≥98% (HPLC and TLC)
3-IODOBENZYL-GUANIDINE HEMISULFATE ≥98% (HPLC and TLC) |
87862-25-7 |
25mg |
￥95400 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
I9890 |
≥98% (HPLC and TLC)
3-IODOBENZYL-GUANIDINE HEMISULFATE ≥98% (HPLC and TLC) |
87862-25-7 |
5mg |
￥24720 |
2021-03-23 |
購入 |
|
Sigma-Aldrich Japan
|
I0328000 |
European Pharmacopoeia (EP) Reference Standard
3-IODOBENZYL-GUANIDINE HEMISULFATE European Pharmacopoeia (EP) Reference Standard |
87862-25-7 |
|
￥35200 |
2021-03-23 |
購入 |
3-IODOBENZYL-GUANIDINE HEMISULFATE 化學(xué)特性,用途語,生産方法
説明
m-Iodobenzylguanidine (MIBG) is an analogue of norepinephrine with anticancer activity. It inhibits cell growth in a panel of human and mouse leukemia, fibrosarcoma, melanoma, and neuroblastoma cell lines when used at a concentration of 20 μg/ml and reduces clonogenic survival of L1210 leukemia cells in a concentration-dependent manner. MIBG increases survival in N
1E155 and L1210 mouse xenograft models when administered at doses of 40 and 20 mg/kg, respectively. It selectively accumulates in chromaffin tissues and tumors and formulations containing radiolabeled forms of MIBG have been used as imaging agents in the diagnosis and treatment of neuroendocrine tumors. MIBG also inhibits ADP-ribose linkage to membrane proteins in turkey erythrocyte membranes.
化學(xué)的特性
Colourless to off-white solid
使用
m-Iodobenzylguanidine Hemisulfate?can be used to demethylate and oxidize membrane-associated DNA. It has also been employed to develop a cell-based high-throughput screening assay to identify anti-hepatitis C virus compounds.
3-IODOBENZYL-GUANIDINE HEMISULFATE 上流と下流の製品情報
原材料
準(zhǔn)備製品
3-IODOBENZYL-GUANIDINE HEMISULFATE 生産企業(yè)
Global( 28)Suppliers
- 87862-25-7
- M-IBG
- MIBG HEMISULFATE SALT
- M-IODOBENZYLGUANIDINE HEMISULFATE SALT
- M-IODOBENZYLGUANIDINE 1/2H2SO4
- Guanidine, [(3-iodophenyl)methyl]-, sulfate (2:1)
- meta-Iodobenzylguanidine hemisulfate
- MIBG hemisulfate
- m-iodobenzylguanidine sulfate
- 3-IODOBENZYLGUANIDINE HEMISULPHATE
- 3-IODOBENZYL-GUANIDINE HEMISULFATE
- Iobenguane sulfate CRS
- Iobenguane Hemisulfate
- MIBG sulfate
- 1-(3-Iodobenzyl)guanidine hemis ulfate
- m-Iodo benzyl guanidine, hemisulphate, 99%
- Iobenguane sulfate，m-Iodobenzylguanidine (hemisulfate)
- Guanidine,[(3-iodChemicalbookophenyl)methyl]-,sulfate(2:1)
- proliferation,survival,tumors,MIBG,Iobenguane,mono(ADP-ribosylation),Iobenguane sulfate,inhibit,cytotoxic,analogue,antitumor,Inhibitor,adrenergic
- Nafamostat Impurity 14
- Guanidine, N-[(3-iodophenyl)methyl]-, sulfate (2:1)