indicine-N-oxide
- CAS No.
- 41708-76-3
- Chemical Name:
- indicine-N-oxide
- Synonyms
- NSC132319;Indicin-N-oxid;indicine-N-oxide;Indicine N-oxide-RM;(+)-Indicine N-oxide;DNAWGBOKUFFVMB-PZIGJSDBSA-N;(7R,8R)-7-hydroxy-4-oxido-5,6,7,8-tetrahydro-3H-pyrrolizin-4-ium-1-yl]methyl (2R)-2-hydroxy-2-[(1S)-1-hydroxyethyl]-3-methylbutanoate;Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, [(1R,7aS)-2,3,5,7a-tetrahydro-1-hydroxy-4-oxido-1H-pyrrolizin-7-yl]methyl ester, (2R,3S)-
- CBNumber:
- CB91364920
- Molecular Formula:
- C15H25NO6
- Molecular Weight:
- 315.36
- MDL Number:
- MFCD00866484
- MOL File:
- 41708-76-3.mol
| Melting point | 130.5°C (rough estimate) |
|---|---|
| Boiling point | 454.91°C (rough estimate) |
| Density | 1.1359 (rough estimate) |
| refractive index | 1.5000 (estimate) |
| pka | 12.54±0.29(Predicted) |
| FDA UNII | 69L6IW0Y7P |
| NCI Drug Dictionary | indicine-N-oxide |
indicine-N-oxide price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL83235 | Indicine N-oxide phyproof? Reference Substance | 41708-76-3 | 10MG | $916 | 2024-03-01 | Buy |
| TRC | I521105 | IndicineN-Oxide | 41708-76-3 | 5mg | $1260 | 2021-12-16 | Buy |
| TRC | I521105 | IndicineN-Oxide | 41708-76-3 | 0.5mg | $160 | 2021-12-16 | Buy |
| Usbiological | 452316 | Indicine N-Oxide | 41708-76-3 | 500ug | $460 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0011660 | INDICINE-N-OXIDE 95.00% | 41708-76-3 | 5MG | $501.73 | 2021-12-16 | Buy |
indicine-N-oxide Chemical Properties,Uses,Production
Description
Heliotropiurn indicurn also contains this base which has the structure given above based upon comparison with the preceding alkaloid. The base has proved to be highly active against transplanted neoplasts, Walker-256 carcinosarcoma, melanoma B-16, leukaemia L-12l 0, leukaemia P-388 and leukaemia P-1534 in mice and rats, giving up to 91 per cent inhibition of transplanted growth at a daily dosage of 200 mgm. per kilo.
Uses
Indicine N-oxide is a pyrrolizidine alkaloid that is isolated from Heliotropium indicum, one of the most widely used herbs in India. Indicine N-oxide exhibits antitumour and antimitotic activity in humans, and has subsequently undergone Phase I & II trials in adults and children with leukemia and solid tumours.
References
Rao, McBride., U.S. Patent, 3,717,710 February 20,1973
indicine-N-oxide Preparation Products And Raw materials
Raw materials
Preparation Products
indicine-N-oxide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94657 | 76 |
| Biyu Biotechnology (Shanghai) Co., ltd | 021-26018599 | China | 270 | 56 | |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
| Chengdu Push Bio-Technology Co., Ltd. | 028-85370565-229 18080489829 | 3004654993@qq.com | China | 8902 | 60 |
| Shenzhen Regent Biochemical Technology Co., Ltd. | 0755-0755-85201366 18938635012 | sales@regentsciences.com | China | 9356 | 58 |
| Nanjing Digger Medical Technology Co. Ltd. | 025-025-51191215 18013836722 | 2399235533@qq.com | China | 4933 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 +86-13028896684; | sales@rrkchem.com | China | 57102 | 58 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 028-81700200 18108052721 | 2850505130@qq.com | China | 5177 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44918 | 58 |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 021-021-61109150 | sales@tcisct.com | China | 31121 | 58 |