Climbazole
- CAS No.
- 38083-17-9
- Chemical Name:
- Climbazole
- Synonyms
- CLIMBAZOL;baypival;Crinipan AD;1-[(4-Chlorophenoxy)(tert-butylcarbonyl)Methyl]iMidazole;1-(4-Chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one;BAYSAN;MEB-6401;climbazo;bay-e6975;Diadimefon
- CBNumber:
- CB8671477
- Molecular Formula:
- C15H17ClN2O2
- Molecular Weight:
- 292.76
- MDL Number:
- MFCD00055505
- MOL File:
- 38083-17-9.mol
Melting point | 96-100°C |
---|---|
Boiling point | 447.5±40.0 °C(Predicted) |
Density | 1.17±0.1 g/cm3(Predicted) |
vapor pressure | 0.001Pa at 25℃ |
refractive index | 1.54 |
storage temp. | Inert atmosphere,Room Temperature |
solubility | Insoluble in water |
form | Solid |
pka | 5.66±0.22(Predicted) |
color | White to Almost white |
Water Solubility | 58mg/L at 25℃ |
BRN | 618020 |
InChIKey | OWEGWHBOCFMBLP-UHFFFAOYSA-N |
LogP | 3.83 at 25℃ |
CAS DataBase Reference | 38083-17-9(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | 9N42CW7I54 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07,GHS09 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302-H410 | |||||||||
Precautionary statements | P301+P312+P330 | |||||||||
Hazard Codes | Xn,N | |||||||||
Risk Statements | 22-50/53 | |||||||||
Safety Statements | 60-61 | |||||||||
RIDADR | UN 3077 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | EL7085000 | |||||||||
HS Code | 29332900 | |||||||||
NFPA 704 |
|
Climbazole price More Price(26)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 36127 | Climbazole PESTANAL?, analytical standard | 38083-17-9 | 100mg | $106 | 2024-03-01 | Buy |
Sigma-Aldrich | 1135600 | Climbazole United States Pharmacopeia (USP) Reference Standard | 38083-17-9 | 400mg | $436 | 2024-03-01 | Buy |
TCI Chemical | C2025 | Climbazole >98.0%(HPLC)(T) | 38083-17-9 | 25g | $60 | 2024-03-01 | Buy |
TCI Chemical | C2025 | Climbazole >98.0%(HPLC)(T) | 38083-17-9 | 500g | $483 | 2024-03-01 | Buy |
Cayman Chemical | 27968 | (±)-Climbazole | 38083-17-9 | 50g | $78 | 2024-03-01 | Buy |
Climbazole Chemical Properties,Uses,Production
Risks to the environment
Climbazole (CBZ) is an emerging recalcitrant contaminant in wastewater, which has severe toxic effects on aquatic organisms.
Description
(±)-Climbazole is an imidazole antifungal agent. It inhibits the growth of C. albicans (MIC = 0.29 μg/ml), as well as clinical isolates of M. pachydermatis (MICs = <0.06-1 μg/ml) and M. furfur (MICs = <0.06-0.5 μg/ml) in vitro. It also reduces the size of Malassezia populations on the skin of naturally infected dogs when used at a dose of 2% in shampoo. (±)-Climbazole (80 mg/kg) increases the levels of cytochrome P450 in rat liver. Formulations containing climbazole have been used in the treatment of dandruff.
Chemical Properties
White Solid
Uses
Climbazole is an imidazole antifungal agent that can provide anti-dandruff benefits when incorporated into a shampoo matrix. s assay and did not induce micronuclei in human lymphocytes.
Definition
ChEBI: 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one is a ketone that is butan-2-one substituted by a 4-chlorophenoxy and a 1H-imidazol-1-yl group at position 1 and 2 methyl groups at position 3. It is a member of monochlorobenzenes, a member of imidazoles, an aromatic ether, a ketone and a hemiaminal ether.
Hazard
Moderately toxic by ingestion. Low toxicity by skin contact.
Flammability and Explosibility
Non flammable
Side effects
May cause localized irritation of the skin with symptoms including redness, rashes and itching.
Climbazole Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
airuikechemical co., ltd. | +undefined86-15315557071 | sales02@sdzhonghuimaterial.com | China | 983 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2986 | 55 |
Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8838 | 58 |
Shandong Zhishang New Material Co., Ltd. | +8617653113209 | sales002@sdzschem.com | China | 3049 | 58 |
Jinan Qinmu Fine Chemical Co.,Ltd. | +8618660799346 | sales@qinmuchem.com | China | 1009 | 58 |
Changzhou AniKare Pharmatech Co., Ltd. | +86-0519-8359-8696 +8618018249389 | sales@anikare.com | China | 9302 | 58 |
Hebei Shengyang Water Conservancy Engineering Co., Ltd. | +8615373025980 | clara@hbshengyang.com | China | 875 | 58 |
Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-17333973358 | sales06@hbduling.cn | China | 8051 | 58 |
SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8810 | 58 |
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View Lastest Price from Climbazole manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-12-22 | Climbazole
38083-17-9
|
US $999.00-666.00 / kg | 1kg | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | ||
2024-12-20 | Climbazole
38083-17-9
|
US $6.00 / kg | 1kg | 99% | 2000KG/Month | HebeiShuoshengImportandExportco.,Ltd | ||
2024-12-20 | Climbazole
38083-17-9
|
US $0.00 / KG | 1KG | ≥99.5% | 200mt/year | Jinan Finer Chemical Co., Ltd |
- Climbazole
38083-17-9
- US $999.00-666.00 / kg
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
- Climbazole
38083-17-9
- US $6.00 / kg
- 99%
- HebeiShuoshengImportandExportco.,Ltd
- Climbazole
38083-17-9
- US $0.00 / KG
- ≥99.5%
- Jinan Finer Chemical Co., Ltd