ChemicalBook >> CAS DataBase List >>Triphenylphosphine oxide
Triphenylphosphine oxide
- CAS No.
- 791-28-6
- Chemical Name:
- Triphenylphosphine oxide
- Synonyms
- TPO;TPPO;Ph3PO;TTPO;Triphenylphosphinoxid;triphenylphosphane oxide;Trisphenylphosphine oxide;Triphenyl phosphorus oxide;Orlistat Related CoMpound C;PP 560
- CBNumber:
- CB8296821
- Molecular Formula:
- C18H15OP
- Molecular Weight:
- 278.28
- MDL Number:
- MFCD00002080
- MOL File:
- 791-28-6.mol
- MSDS File:
- SDS
Last updated:2024-12-18 14:15:32
| Melting point | 150-157 °C(lit.) |
|---|---|
| Boiling point | 360 °C |
| Density | 1,212 g/cm3 |
| vapor pressure | <1 hPa (50 °C) |
| Flash point | 180 °C |
| storage temp. | Store below +30°C. |
| solubility | methanol: 25 mg/mL, clear |
| form | Crystalline Powder or Flakes |
| color | White to pink-brown |
| Specific Gravity | 1.212 |
| Water Solubility | slightly soluble |
| Hydrolytic Sensitivity | 4: no reaction with water under neutral conditions |
| BRN | 745854 |
| LogP | 2.8 |
| CAS DataBase Reference | 791-28-6(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | Z69161FKI3 |
| NIST Chemistry Reference | (C6H5)3PO(791-28-6) |
| EPA Substance Registry System | Triphenylphosphine oxide (791-28-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H290 | |||||||||
| Precautionary statements | P234-P390 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37/38-52/53 | |||||||||
| Safety Statements | 26-61-36 | |||||||||
| RIDADR | 3077 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | SZ1676000 | |||||||||
| Autoignition Temperature | 590 °C | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 9 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29310095 | |||||||||
| Toxicity | LD50 orally in Rabbit: 685 mg/kg | |||||||||
| NFPA 704 |
|
Triphenylphosphine oxide price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR2544 | Orlistat Related Compound C Pharmaceutical Secondary Standard; Certified Reference Material | 791-28-6 | 50MG | $602 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1478833 | Orlistat Related Compound C United States Pharmacopeia (USP) Reference Standard | 791-28-6 | 25mg | $1490 | 2024-03-01 | Buy |
| Sigma-Aldrich | 08902 | Triphenylphosphine oxide analytical standard | 791-28-6 | 100mg | $151 | 2024-03-01 | Buy |
| TCI Chemical | T0625 | Triphenylphosphine Oxide >98.0%(GC) | 791-28-6 | 25g | $27 | 2024-03-01 | Buy |
| TCI Chemical | T0625 | Triphenylphosphine Oxide >98.0%(GC) | 791-28-6 | 100g | $58 | 2024-03-01 | Buy |
Triphenylphosphine oxide Chemical Properties,Uses,Production
Description
Triphenylphosphine oxide (TPPO) is a coordinating solvent used to activate crystallization of chemical compounds. It has been used in flame retardant applications, as an epoxy cure catalyst, and more recently, to produce nanostructures.
Chemical Properties
White solid
Uses
Triphenylphosphine oxide can be used:
As a catalyst in Appel-type chlorination reaction of acyclic primary and secondary alcohols.
As a catalyst in stereoselective poly and dibromination of α,β-unsaturated esters and β,γ-unsaturated α-ketoester compounds.
As a promotor in the diastereoselective synthesis of α-ribofuranosides through ribofuranosylation of alcohols with ribofuranosyl iodides.
Uses
Triphenylphosphine Oxide (Orlistat USP Related Compound C) is a catalyst in the conversion of aldehydes into 1,1-dichlorides. Triphenylphosphine Oxide is used as a catalyst for the synthesis of hightly functionalized α-CF3 γ-keto esters.
Uses
Triphenylphosphine oxide is a phosphine ligand used for coupling reactions, epoxidations, and Michael reactions
Definition
ChEBI: A phosphine oxide in which the substituents on phosphorus are three phenyl groups.
Synthesis Reference(s)
Tetrahedron Letters, 31, p. 5463, 1990 DOI: 10.1016/S0040-4039(00)97873-0
Flammability and Explosibility
Not classified
Purification Methods
It crystallises from absolute EtOH and is dried in vacuo. The gold chloride complex has m 177.5-178.5o. [Addison & Sheldon J Chem Soc 2705 1956, Cox & Westheimer J Am Chem Soc 80 5441 1958, Beilstein 16 III 864, 16 1011.]
Triphenylphosphine oxide Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
4-Fluorothiophenol
1-METHYLTHYMINE
Diethyl acetylenedicarboxylate
Triphenylphosphine
2,4,6-TRINITROANILINE
1of3
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Related articles
- Applications of Triphenylphosphine oxide
- Triphenylphosphine oxide (often abbreviated TPPO) is the organophosphorus compound with the formula OP(C6H5)3. This colourless....
- Nov 6，2019
View Lastest Price from Triphenylphosphine oxide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-12-20 | Triphenylphosphine oxide
791-28-6
|
US $10.00 / kg | 1kg | 99% | 5000 | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2024-12-13 | Triphenylphosphine oxide
791-28-6
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-11-21 | Triphenylphosphine oxide
791-28-6
|
US $1.00 / kg | 1kg | 99% | 10 mt | Hebei Weibang Biotechnology Co., Ltd |
-
- Triphenylphosphine oxide
791-28-6
- US $10.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- Triphenylphosphine oxide
791-28-6
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Triphenylphosphine oxide
791-28-6
- US $1.00 / kg
- 99%
- Hebei Weibang Biotechnology Co., Ltd
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791-28-6