2-Cyanoacetamide
- CAS No.
- 107-91-5
- Chemical Name:
- 2-Cyanoacetamide
- Synonyms
- CYANOACETAMIDE;ACETAMIDE, 2-CYANO-;Cyanacetamide;Kyanacetamid;CYANOACETIC AMIDE;CYAC;2-CAA;usafkf-14;USAF kf-14;Cyanacetamid
- CBNumber:
- CB7852727
- Molecular Formula:
- C3H4N2O
- Molecular Weight:
- 84.08
- MDL Number:
- MFCD00008024
- MOL File:
- 107-91-5.mol
- MSDS File:
- SDS
| Melting point | 119-121 °C(lit.) |
|---|---|
| Boiling point | 154.34°C (rough estimate) |
| Density | 1,4 g/cm3 |
| refractive index | 1.5110 (estimate) |
| Flash point | 419 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | cold water: soluble1gm in 6.5ml |
| form | Crystalline Powder |
| pka | -1.27±0.10(Predicted) |
| color | White to light cream |
| Odor | Odorless |
| Water Solubility | soluble |
| Merck | 14,2688 |
| BRN | 878221 |
| CAS DataBase Reference | 107-91-5(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | YBK38G2YXH |
| NIST Chemistry Reference | Acetamide, 2-cyano-(107-91-5) |
| EPA Substance Registry System | 2-Cyanoacetamide (107-91-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38-20/21/22 | |||||||||
| Safety Statements | 22-26-28A | |||||||||
| RIDADR | UN 3439 6.1/PG 3 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | AB5950000 | |||||||||
| TSCA | Yes | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29159080 | |||||||||
| HS Code | 29269095 | |||||||||
| Hazardous Substances Data | 107-91-5(Hazardous Substances Data) | |||||||||
| NFPA 704 |
|
2-Cyanoacetamide price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 108448 | Cyanoacetamide 99% | 107-91-5 | 100g | $62.7 | 2024-03-01 | Buy |
| Sigma-Aldrich | 108448 | Cyanoacetamide 99% | 107-91-5 | 500g | $201 | 2024-03-01 | Buy |
| TCI Chemical | C0437 | 2-Cyanoacetamide >98.0%(GC) | 107-91-5 | 25g | $22 | 2024-03-01 | Buy |
| TCI Chemical | C0437 | 2-Cyanoacetamide >98.0%(GC) | 107-91-5 | 500g | $90 | 2024-03-01 | Buy |
| Alfa Aesar | A12482 | Cyanoacetamide, 99% | 107-91-5 | 100g | $32.1 | 2024-03-01 | Buy |
2-Cyanoacetamide Chemical Properties,Uses,Production
Chemical Properties
White or light yellow needle crystal or powder. Slightly soluble in water, easily soluble in ethanol.
Uses
2-Cyanoacetamide was used in spectrofluorimetric method for the determination of some antihistaminic H1 receptor antagonist drugs such as ebastine, cetirizine dihydrochloride and fexofenadine hydrochloride. It may be used in fluorometric determination of 3,4-dihydroxyphenylalanine. It was used as post column fluorigenic derivatizing agent for the bio-analysis and pharmacokinetics of chitosan ester in rabbit serum. Cyanoacetamide is the starting reagent for vitamin B6 synthesis. It reacts with reducing carbohydrates in borate buffer to give intense fluorescence and is useful for the automated analysis of carbohydrates as borate complexes. It can also be used in the synthesis of heterocyclic compounds such as pyrazole, pyridine and pyrimidine derivatives. Moreover, it can also be applied for the spectrophotometric assay of the enzyme activity of cellulose in related host cells.
Preparation
Cyanoacetamide can be prepared from ethyl cyanoacetate and ammonia. Cool the ethyl cyanoacetate to below 200°C, add concentrated ammonia water to react, and the mixture turns from turbid to clear. After cooling in cold water for 20 minutes, a precipitate is precipitated. After filtration and drying, the crude product is obtained, and then the crude product of cyanoacetamide is added. In the boiling ethanol, after dissolving it, add a small amount of activated carbon for decolorization and purification, filter, cool the filtrate to separate out the precipitate, and dry it at 80-100 ℃ to obtain the fine cyanoacetamide.
Definition
2-Cyanoacetamide is an acetic amide with a nitrile functional group. It is a codon of glutamine that directs the placement of glutamine into a polypeptide.
General Description
Cyanoacetamide is the starting reagent for vitamin B6 synthesis. It reacts with reducing carbohydrates in borate buffer to give intense fluorescence andis useful for the automated analysis of carbohydrates as borate complexes.
Purification Methods
Crystallise the amide from MeOH/dioxane (6:4), then water and dry it over P2O5 under vacuum. [Beilstein 2 IV 1891.]
2-Cyanoacetamide Preparation Products And Raw materials
Raw materials
Preparation Products
1of7
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Sinoda Biological Technology Co., Ltd | +8613401983379 | sales@njmcn.cn | CHINA | 74 | 58 |
| ENBRIDGE PHARMTECH CO., LTD. | +8613812269233 | tinayang@enbridgepharm.com | China | 322 | 58 |
| Suzhou Yuanrui Bio-Tech Co., Ltd | +86-18106132862 +86-18106132862 | sales02@yuanruibio.com | China | 285 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5889 | 58 |
| HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +8615350851019 | admin@86-ss.com | China | 1001 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 +86-16264648883 | niki@zlchemi.com | China | 2691 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2986 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
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View Lastest Price from 2-Cyanoacetamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-12-22 | 2-Cyanoacetamide
107-91-5
|
US $999.00-666.00 / kg | 1kg | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | |
 |
2024-12-20 | 2-Cyanoacetamide
107-91-5
|
US $10.00 / kg | 1kg | 99% | 20 ton | Hebei Zhuanglai Chemical Trading Co Ltd | |
 |
2024-12-20 | 2-Cyanoacetamide (CAA)
107-91-5
|
US $0.00 / KG | 1KG | 99% | 2000mt | Jinan Finer Chemical Co., Ltd |
-
- 2-Cyanoacetamide
107-91-5
- US $999.00-666.00 / kg
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
-
- 2-Cyanoacetamide
107-91-5
- US $10.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
-
- 2-Cyanoacetamide (CAA)
107-91-5
- US $0.00 / KG
- 99%
- Jinan Finer Chemical Co., Ltd