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ChemicalBook >> CAS DataBase List >>42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin

42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin

CAS No.
143030-02-8
Chemical Name:
42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin
Synonyms
Rapamycin Impurity 32;42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin;Rapamycin, 42-O-[(1,1-dimethylethyl)dimethylsilyl]-;Clobetasone Butyrate Impurity 9 (Clobetasone Butyrate EP Impurity I)
CBNumber:
CB75177306
Molecular Formula:
C57H93NO13Si
Molecular Weight:
1028.45
MDL Number:
MOL File:
143030-02-8.mol
Last updated:2023-04-23 13:52:06

42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin Properties

Boiling point 977.0±75.0 °C(Predicted)
Density 1.12±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Dichloromethane, Methanol
form Solid
pka 10.40±0.70(Predicted)
color White

42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D479400 42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin 143030-02-8 25mg $735 2021-12-16 Buy
Product number Packaging Price Buy
D479400 25mg $735 Buy

42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin Chemical Properties,Uses,Production

Uses

42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin is an intermediate in the synthesis of 8-O-Methyl-rapamycin which is a derivative of Rapamycin (R124000), a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants.

42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin Preparation Products And Raw materials

Raw materials

Preparation Products

42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanning Saifir Biotechnology Co., Ltd. 18877121284 1309367106@qq.com China 261 58
Shandong WorldSun Biological Technology Co., Ltd. 0531-88723173 18596073690 1047208234@qq.com China 4376 58
Hubei Xinyang Medical Technology Co., Ltd 15347293736 15347293736 2853117764@qq.com China 8328 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44918 58
Wuhan Acumen Bio-Technology Co.,ltd 027-027-16602739303 16602739303 673003916@qq.com China 3059 58
guoyungurui 18162595016; 18162595016 3287908757@qq.com China 10336 58
United States Biological -- sales@advtechind.com United States 6075 58
42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin Rapamycin Impurity 32 Rapamycin, 42-O-[(1,1-dimethylethyl)dimethylsilyl]- Clobetasone Butyrate Impurity 9 (Clobetasone Butyrate EP Impurity I) 143030-02-8