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ChemicalBook >> CAS DataBase List >>BMS-8

BMS-8

CAS No.
1675201-90-7
Chemical Name:
BMS-8
Synonyms
BMS-8;PPI,BMS 8,BMS8,inhibit,BMS-8,Inhibitor,PD-L1,PD-1;1-(3-bromo-4-((2-methylbiphenyl-3-yl)methoxy)benzyl)piperidine-2-carboxylic acid;1-(3-Bromo-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylic acid;1-(3-Bromo-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylic acid;2-Piperidinecarboxylic acid, 1-[[3-bromo-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl]methyl]-
CBNumber:
CB74666331
Molecular Formula:
C27H28BrNO3
Molecular Weight:
494.42
MDL Number:
MFCD31714164
MOL File:
1675201-90-7.mol
Last updated:2024-11-12 16:52:33

BMS-8 Properties

Boiling point 616.9±55.0 °C(Predicted)
Density 1.334±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Methanol: slightly soluble
form A crystalline solid
pka 2.35±0.20(Predicted)
color White to off-white

BMS-8 price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 22355 BMS-8 ≥98% 1675201-90-7 1mg $26 2024-03-01 Buy
Cayman Chemical 22355 BMS-8 ≥98% 1675201-90-7 25mg $542 2024-03-01 Buy
Cayman Chemical 22355 BMS-8 ≥98% 1675201-90-7 500μg $25 2021-12-16 Buy
Cayman Chemical 22355 BMS-8 ≥98% 1675201-90-7 5mg $122 2024-03-01 Buy
Cayman Chemical 22355 BMS-8 ≥98% 1675201-90-7 10mg $230 2024-03-01 Buy
Product number Packaging Price Buy
22355 1mg $26 Buy
22355 25mg $542 Buy
22355 500μg $25 Buy
22355 5mg $122 Buy
22355 10mg $230 Buy

BMS-8 Chemical Properties,Uses,Production

Description

BMS-8 is a small molecule inhibitor of the protein-protein interaction between programmed death protein 1 (PD-1) and its ligand programmed cell death ligand 1 (PD-L1) with an IC50 value of 146 nM in a homogeneous time-resolved fluorescence (HTRF) binding assay.

Uses

BMS-8 is inhibitor of the PD-1/PD-L1 interaction by inducing PD-L1 dimerization through PD-1 interacting surface, binding at a hydrophobic cavity formed upon PD-L1 dimerization.

BMS-8 Preparation Products And Raw materials

Raw materials

Preparation Products

BMS-8 Suppliers

Global( 24)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32079 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52925 58
InvivoChem 13549236410 sales@invivochem.cn China 6753 58
Suzhou Zhixin Biotechnology Co., Ltd. 0512-65118909 15162312715 sales@szzxbio.com China 3004 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3466 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686 sales@rechemscience.com China 2994 58
MQ (shanghai) Pharmaceuticals Co., Ltd. 13761635123 1014988033@qq.com China 4969 55
Tianjin heowns Biochemical Technology Co., Ltd. 400-6387771-6038 18902104717 sales@heowns.com China 21070 60

View Lastest Price from BMS-8 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BMS-8 pictures 2024-11-12 BMS-8
1675201-90-7
 US $33.00-133.00 / mg 99.06% 10g TargetMol Chemicals Inc.
  • BMS-8 pictures
  • BMS-8
    1675201-90-7
  • US $33.00-133.00 / mg
  • 99.06%
  • TargetMol Chemicals Inc.
BMS-8 2-Piperidinecarboxylic acid, 1-[[3-bromo-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl]methyl]- 1-(3-bromo-4-((2-methylbiphenyl-3-yl)methoxy)benzyl)piperidine-2-carboxylic acid PPI,BMS 8,BMS8,inhibit,BMS-8,Inhibitor,PD-L1,PD-1 1-(3-Bromo-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylic acid 1-(3-Bromo-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylic acid 1675201-90-7