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ChemicalBook >> CAS DataBase List >>Glycitein

Glycitein

CAS No.
40957-83-3
Chemical Name:
Glycitein
Synonyms
Gycitein;GLYCITEIN;GLYCETEIN; Glicetein;Glycitein-RM;Glycitein(SH);Glycitein, >=98%;Glycitein (15 mg);Glycitein USP/EP/BP;GLYCITEIN,FROMSOYBEAN
CBNumber:
CB7253674
Molecular Formula:
C16H12O5
Molecular Weight:
284.26
MDL Number:
MFCD00016679
MOL File:
40957-83-3.mol
Last updated:2024-10-30 18:52:02

Glycitein Properties

Melting point >300°C
Boiling point 547.4±50.0 °C(Predicted)
Density 1.420±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility Aqueous Base (Slightly), DMSO (Slightly)
pka 7.03±0.20(Predicted)
form Solid
color Light Brown
InChIKey DXYUAIFZCFRPTH-UHFFFAOYSA-N
LogP 2.570 (est)
CAS DataBase Reference 40957-83-3(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 92M5F28TVF

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS06
Signal word  Danger
Hazard statements  H301-H311-H314-H331
Precautionary statements  P260-P264-P270-P271-P280-P301+P330+P331-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P310-P403+P233-P405-P501
Hazard Codes  Xi
Safety Statements  24/25
WGK Germany  3
HS Code  29329990

Glycitein price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHL89692 Glycitein phyproof? Reference Substance 40957-83-3 10mg $316 2024-03-01 Buy
Sigma-Aldrich 43534 Glycitein analytical standard 40957-83-3 10mg $323 2024-03-01 Buy
Sigma-Aldrich 1295844 Glycitein United States Pharmacopeia (USP) Reference Standard 40957-83-3 15mg $1110 2024-03-01 Buy
Cayman Chemical 14162 Glycitein ≥98% 40957-83-3 5mg $49 2024-03-01 Buy
Cayman Chemical 14162 Glycitein ≥98% 40957-83-3 10mg $92 2024-03-01 Buy
Product number Packaging Price Buy
PHL89692 10mg $316 Buy
43534 10mg $323 Buy
1295844 15mg $1110 Buy
14162 5mg $49 Buy
14162 10mg $92 Buy

Glycitein Chemical Properties,Uses,Production

Description

Glycitein is an O-methylated isoflavone that comprises 5-10% of the total isoflavones in soy food products. This phytoestrogen is reported to have weak estrogenic activity, displacing estradiol binding at the estrogen receptor in vitro with an IC50 value of 3.94 μM. It suppresses the proliferation of osteoblasts and promotes differentiation from its progenitor. It has also been used to attenuate proliferation (10 μM) of aortic smooth muscle cells related to atherosclerotic vascular change in stroke-prone hypertensive rats and to protect against beta amyloid (Aβ)-induced toxicity and oxidative stress (100 μg/ml) in C. elegans expressing human Aβ.

Chemical Properties

Pale Orange Solid

Uses

Glycitein has been used as standard for the analysis of soy isoflavones and metabolites in urine. It has also been used to bind to recombinant estrogen and progesterone receptors to know the relative binding affinity (RBA) for detection of potential endocrine disruptors.

Uses

The compund shows an anti-cancer activity, plasma cholesterol reduction, reduction in postmenopausal bone loss

Uses

Glycitein may be used as a reference standard in the determination of glycitein in hydrolyzed dry soya extracts using reversed-phase high-performance liquid chromatography (RP-HPLC).

Definition

ChEBI: A methoxyisoflavone that is isoflavone substituted by a methoxy group at position 6 and hydroxy groups at positions 7 and 4'. It has been isolated from the mycelia of the fungus Cordyceps sinensis.

General Description

Glycitein is an isoflavone found in soy food products.

Biochem/physiol Actions

Glycitein is a soybean (yellow cultivar) isoflavonoid; its natural glycosides are synergistic with genistein in inducing specific gene expression. Glycitein may be used to study anti-oxidation processes at the level of gene transcription where it increases the binding of transcription factors [nuclear factor-E2-related factor 2 (Nrf2) and c-Jun] to the antioxidant response element (ARE) on HO-1 and NQO1 promoters. Glycitein may be used in combination with other isoflavonoids such as genistein and daidzein to study apoptosis.

621-59-0
40957-83-3
Synthesis of Glycitein from Isovanillin
Global( 292)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20288 58
Shanghai Zheyan Biotech Co., Ltd. 		18017610038 zheyansh@163.com CHINA 3619 58
Chengdu Greenpure Biopharma CO.,Ltd 		18283602253; +8618283602253 jancyzheng@gcgreenpure.com China 953 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29886 58
Chengdu Biopurify Phytochemicals Ltd. 		+8618080483897 sales@biopurify.com China 3772 58
Nanjing Dolon Biotechnology Co.,Ltd. 		18905173768 sales@dolonchem.com CHINA 2972 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
Shaanxi Pioneer Biotech Co., Ltd . 		+8613259417953 sales@pioneerbiotech.com China 3000 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58

View Lastest Price from Glycitein manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Glycitein pictures 2024-10-30 Glycitein
40957-83-3
 US $50.00 / mL 99.57% 10g TargetMol Chemicals Inc.
Glycitein pictures 2024-03-29 Glycitein
40957-83-3
 US $8.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
Glycitein pictures 2023-02-24 Glycitein
40957-83-3
 US $0.00 / mg 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
  • Glycitein pictures
  • Glycitein
    40957-83-3
  • US $50.00 / mL
  • 99.57%
  • TargetMol Chemicals Inc.
  • Glycitein pictures
  • Glycitein
    40957-83-3
  • US $8.00-1.00 / KG
  • 99%
  • Henan Fengda Chemical Co., Ltd
  • Glycitein pictures
  • Glycitein
    40957-83-3
  • US $0.00 / mg
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.

Glycitein Spectrum

GLYCETEIN GLYCITEIN 4',7-DIHYDROXY-6-METHOXYISOFLAVONE 4,7-DIHYDROXY-6-METHOXYISOFLAVONE 7,4'-DIHYDROXY-6-METHOXYISOFLAVONE Glicetein 7-Hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy- 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-chromen-4-one Glycitein, >=98% 4μ,7-Dihydroxy-6-methoxyisoflavone, Glycetein 3-(4-Hydroxyphenyl)-6-methoxy-7-hydroxy-4H-1-benzopyran-4-one Glycitein,4′,7-Dihydroxy-6-methoxyisoflavone, Glycetein Glycitein (15 mg) GLYCITEIN,FROMSOYBEAN Glycitein, 98%, from soybean Glycitein USP/EP/BP Gycitein Glycitein, ≥97% (HPLC) Glycitein (P) (Compendial Traceable) 4',7- Dihydroxy -6-methoxy Isoflavone (or ) GLYCITIN 7-Hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one Coumarin Impurity 9 (Coumarin 30) GLYCITEIN (Compendial Traceable) Glycitein(SH) Glycitein-RM 40957-83-3 40957-83-0 Nucleoside Analogs Nucleosides, Nucleotides, Oligonucleotides Biochemicals and Reagents BioChemical Intermediates & Fine Chemicals Pharmaceuticals The group of Daidzin inhibitor chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Iso-Flavones