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ChemicalBook >> CAS DataBase List >>(1S,2R)-(-)-cis-1-Amino-2-indanol

(1S,2R)-(-)-cis-1-Amino-2-indanol

CAS No.
126456-43-7
Chemical Name:
(1S,2R)-(-)-cis-1-Amino-2-indanol
Synonyms
(1S,2R)-1-AMINO-2,3-DIHYDRO-1H-INDEN-2-OL;(1S,2R)-1-AMINO-2-INDANOL;(1S,2R)-CIS-1-AMINO-2-INDANOL;(1S,2R)-(-)-1-AMINO-2-INDANOL;CIS-(1S,2R)-1-AMINO-2-INDANOL;(1S;3aR;(1S,2R) -(−KT-1-Amino-2-indanol-0001;(1S,2R)-1-AMINO-INDAN-2-OL
CBNumber:
CB6417161
Molecular Formula:
C9H11NO
Molecular Weight:
149.19
MDL Number:
MFCD00216655
MOL File:
126456-43-7.mol
MSDS File:
SDS
Last updated:2025-01-27 09:38:02

(1S,2R)-(-)-cis-1-Amino-2-indanol Properties

Melting point 118-121 °C(lit.)
alpha -62 º (c=0.5, CHCl3)
Boiling point 270.27°C (rough estimate)
Density 1.0753 (rough estimate)
refractive index 1.5760 (estimate)
RTECS NK7525500
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility soluble in Methanol
form Powder
pka 14.79±0.40(Predicted)
color White to light beige
optical activity [α]20/D 61°, c = 0.5 in chloroform
Water Solubility slightly soluble
Sensitive Air Sensitive
BRN 4292559
InChIKey LOPKSXMQWBYUOI-BDAKNGLRSA-N
CAS DataBase Reference 126456-43-7(CAS DataBase Reference)
FDA UNII LU3GK925A8
UNSPSC Code 12352116
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21/22
Safety Statements  26-36-36/37/39
RIDADR  3259
WGK Germany  3
F  10-23
TSCA  No
HazardClass  8
HS Code  29052900
NFPA 704
0
2 0

(1S,2R)-(-)-cis-1-Amino-2-indanol price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 440833 (1S,2R)-(?)-cis-1-Amino-2-indanol 99% 126456-43-7 1g $26 2024-03-01 Buy
Sigma-Aldrich 440833 (1S,2R)-(?)-cis-1-Amino-2-indanol 99% 126456-43-7 5g $27.1 2024-03-01 Buy
TCI Chemical A1624 (1S,2R)-(-)-1-Amino-2-indanol >98.0%(GC)(T) 126456-43-7 1g $30 2024-03-01 Buy
TCI Chemical A1624 (1S,2R)-(-)-1-Amino-2-indanol >98.0%(GC)(T) 126456-43-7 5g $131 2024-03-01 Buy
Alfa Aesar H32066 (1S,2R)-(-)-cis-1-Amino-2-indanol, 97% 126456-43-7 5g $146.65 2024-03-01 Buy
Product number Packaging Price Buy
440833 1g $26 Buy
440833 5g $27.1 Buy
A1624 1g $30 Buy
A1624 5g $131 Buy
H32066 5g $146.65 Buy

(1S,2R)-(-)-cis-1-Amino-2-indanol Chemical Properties,Uses,Production

Reaction

  1. Ligand component used in the chromium-catalyzed highly selective asymmetric ene reactions between aryl aldehydes and alkoxy- and silyloxyalkenes.
  2. Ligand component for the chromium-catalyzed highly enantioselective o inverse-demand hetero-Diels-Alder reactions of α,β-unsaturated aldehydes.
  3. Ligand component for the magnesium-catalyzed conjugate addition reaction of 1,3-dicarbonyl compounds to nitroalkenes.
  4. Component for stereoselective asymmetric 6π-azaelectrocyclization through the reaction between the (E)-3-
  5. carbonyl-2,4,6-trienal compounds and the (-)-7-alkyl-cis-1-amino-2-indanol derivatives.
  6. Ligand component for palladium-catalzyed asymmetric azaelectrocyclization for the preparation of 2,4-
  7. disubstituted chiral 1,2,5,6-tetrahydropyridines.
  8. Component for organocatalytic conjugate addition of formaldehyde N,N-dialkylhydrazones to β,γ -Unsaturated α-keto esters.
  9. N-Sulfinyl urea organocatalyst component for enantioselective aza-henry reaction.
  10. Component for organocatalytic enantioselective additions of indoles to nitroalkenes.
Reactions of 126456-43-7_1
Reactions of 126456-43-7_2
Reactions of 126456-43-7_3
Reactions of 126456-43-7_4

Chemical Properties

white to light yellow crystal powder

Uses

(1S,2R)-(-)-cis-1-Amino-2-indanol is used as a reagent in the synthesis of heterocyclic compounds as integrase inhibiting antiviral agents. It is also a key intermediate of the HIV protease inhibitor, Indinavir (I525000).

Uses

1S,2R)-(-)-cis-1-Amino-2-indanol may be used to prepare:

  • (-)-1,2,5,6-Tetrahydropyridine by reacting with methyl (E,E)-4-oxo-2-[(2,6,6-trimethylcyclohex-1-enyl)vinyl}but-2-enoate.
  • Oxazaborolidine catalysts, which can catalyze the asymmetric reduction of aromatic ketones with high enantioselectivity.
  • (RS,1S,2R)-(-)-2,4,6-Trimethylbenzenesulfinic acid 1-(2,4,6-trimethylbenzenesulfonylamino)indan-2-yl ester.

General Description

(1S,2R)-(-)-cis-1-Amino-2-indanol is a main constituent of indinavir, a potent HIV (human immunodeficiency virus) protease inhibitor.

(1S,2R)-(-)-cis-1-Amino-2-indanol Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 394)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		+86-15531157085 +86-15531157085 abby@chuanghaibio.com China 8807 58
Hebei Mujin Biotechnology Co.,Ltd 		+86 13288715578 +8613288715578 sales@hbmojin.com China 12821 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29730 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-+86-371-66670886 info@dakenam.com China 19844 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21631 55
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1803 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29865 58
Shanghai Arbor Chemical Co., Ltd. 		021-60451682 act@arborchemical.com CHINA 904 58
Changzhou Ansciep Chemical Co., Ltd. 		+86 519 86305871 sales@ansciepchem.com CHINA 4241 58

View Lastest Price from (1S,2R)-(-)-cis-1-Amino-2-indanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(1S,2R)-(-)-cis-1-Amino-2-indanol pictures 2025-03-21 (1S,2R)-(-)-cis-1-Amino-2-indanol
126456-43-7
 US $100.00 / kg 25kg 99.99% 200ton Hebei Mujin Biotechnology Co.,Ltd
(1S,2R)-(-)-cis-1-Amino-2-indanol pictures 2025-03-21 (1S,2R)-(-)-cis-1-Amino-2-indanol
126456-43-7
 US $5.00 / kg 1kg ≥99% 200mt/year Jinan Finer Chemical Co., Ltd
(1S,2R)-(-)-cis-1-Amino-2-indanol pictures 2025-03-20 (1S,2R)-(-)-cis-1-Amino-2-indanol
126456-43-7
 US $10.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
(1S,2R)-(-)-cis-1-Amino-2-indanol,99% (1S, 2R)-Trans-1-AMino-2-indanol (1S,2R)-(-)-1-Amino-2,3-dihydro-1H-inden-2-ol, (1S,2R)-(-)-1-Aminoindan-2-ol (1S,2R)-1-Amino-2,3-dihydro-inden-2-ol (1S,2R)-(-)-cis-1-Amino-2-indanol ,98% (1S 2R)-(-)-cis-1-AMino-2-indanol 3aR 7aR)-1-((S)-1-(3-(tert-butyldiMethylsilyloxy)-3-Methylbutoxy)ethyl) -7a-Methylhexahydro-1H-inden-4(2H)-one KT-1-Amino-2-indanol-0001 (1S,2R)-(-)-cis-1-Amino-2-indanol (1S,2R)-(-)-cis-1-Amino-2-hydroxyindane (1S,2R)-(-)-1-Amino-2-indanol, >=98% (1S,2R)-1-Amino-2-indanol,99%e.e. (1S,2R)-(-)-CIS-1-AMINO-2-HYDROXYINDANE (1S,2R)-(-)-CIS-1-AMINO-2-INDANOL (1S,2R)-(-)-CIS-1-AMINOINDAN-2-OL (1S,2R)-(+)-CIS-1-AMINOINDAN-2-OL (1S,2R)-(-)-1-AMINO-2-HYDROXYINDAN (1S,2R)-1-AMINO-2-HYDROXYINDANE (1S,2R)-1-AMINO-INDAN-2-OL cis-(1S)-Amino-(2R)-indanol (Is-Cis)L-Amino-2,3-Dihydro-Lh-Inden-2-Ol,IndinavirSulphate, (IS-cis) l-Amino-2,3-Dihydro-lH-Inden-2-ol CIS-(1S,2R)-1-AMINO-INDANE-2-OL (1S,2R)-(1)-cis-1-Amino-2-indanol (1S,2R)-(-)-cis-1-Aminoindan-2-ol,98% (1S,2R)-(-)-CIS-1-AMINO-2-INDANOL 99% (1R,2S)-(-)-cis-a-Amino-2-indanol 5R)-LGH447 dihydrochloride (1S,2R)-(-)-cis-1-Amino-2-hydroxyindane 126456-43-7 (1S,2R)-(-)-cis-1-Amino-2-indanol (1S,2R)-(-)-cis-1-Amino-2-indanol 126456-43-7 (1S,2R)-(-)-1-Amino-2-indanol > 1H-Inden-2-ol, 1-amino-2,3-dihydro-, (1S,2R)- Indinavir Impurity 1 （Indinavir EP Impurity A) (1S,2R)-(-)-cis-1-Amino-2-indanol USP/EP/BP (1S,2R)-(-)-cis-1-Amino-2-indanol, 97%, (1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-aminium (1S,2R)-CIS-1-AMINO-2-INDANOL (1S,2R)-1-AMINO-2,3-DIHYDRO-1H-INDEN-2-OL (1S,2R)-(-)-1-AMINO-2-INDANOL (1S,2R)-1-AMINO-2-INDANOL CIS-(1S,2R)-1-AMINO-2-INDANOL (1S,2R) -(&minus (1S,2R)-(-) -1-amino-2-indenol (1S,2R)-(?)-cis-1-Amino-2-indanol 126456-43-7 126456-43-9 C9H11NO Amino Alcohols (Chiral) Chiral Building Blocks Hydrogenation Organic Building Blocks Chiral Catalysts, Ligands, and Reagents Asymmetric Synthesis Amino Alcohols Chiral Nitrogen organic alcohol Amino Alcohols (Chiral)